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International Journal of Obesity: Get fat, get fat first
Time of Update: 2022-01-08
In addition, increased family obesity risk (eg, parental obesity and prevalence of T2D) is associated with decreased mu-opioid and CB1 receptor density and changes in brain glucose metabolism .
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Stroke: What are the characteristics of brain imaging in patients with minor stroke with obvious blood vessel blockage?
Time of Update: 2022-01-08
thrombusThe INTERRSeCT study (determining a new method for optimizing thrombus characteristics to predict early recanalization and reperfusion of intravenous alteplase and other treatments, using continuous CT angiography) is a multicenter international prospective imaging cohort that studies acute deficiency Recanalization of patients with bloody stroke and intracranial occlusion in computed tomography (CT) angiography .
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Schizophr Bull: Abnormalities in the ventral striatal cortex may reflect the risk of 22q11.2 deletion syndrome
Time of Update: 2022-01-08
Previous studies on patients with mental illnesses without missing have found that dopaminergic dysfunction in the striatum and the connection disorder of the striatal cortex system are important mechanisms for the emergence of psychosis .
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One case report of successful treatment of refractory intracranial venous sinus thrombosis with balloon angioplasty
Time of Update: 2022-01-08
It is reported that a patient diagnosed with CVST, whose condition deteriorated after heparin anticoagulation, was treated with balloon angioplasty for right sigmoid sinus vein thrombosis .
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JAHA: The relationship between sleep awakening and hypertension in patients with obstructive sleep apnea
Time of Update: 2022-01-08
Repeated awakening during sleep is independently associated with the prevalence of hypertension in OSA patients .
Association Between Arousals During Sleep and Hypertension Among Patients With Obstructive Sleep Apnea .
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How long does it take for fun science running to be effective?
Time of Update: 2022-01-08
Only 10 minutes of moderate-intensity running can increase the local blood flow to different points of the prefrontal cortex (the part of the brain that plays an important role in controlling emotions and executive functions), which is beneficial to improve mental health and enhance executive ability.
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Neurosurgery: venous pulsatile tinnitus
Time of Update: 2022-01-08
C. Cerebral venography showed severe stenosis at the distal end of the right sigmoid sinus .
C. The MRV MIP image shows the right high jugular bulb:Figure 7.
C. The MRV MIP image shows the right high jugular bulb:Figure 7.
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Microbiome: Eating less dietary fiber can cause cognitive dysfunction
Time of Update: 2022-01-08
Supplementation of SCFAs can improve the cognitive function of FD mice, reduce the loss of synaptic proteins, inhibit microglia activation and phagocytic synapses, and partially restore the homeostasis of the intestinal tract of FD mice, and prevent the intestine caused by dietary fiber lack of diet- Brain axis dysfunction .
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Professor Yang Qingwu, JAMA Sub-Journal: The endovascular treatment of patients with acute basilar artery occlusion has significantly improved the good outcome!
Time of Update: 2022-01-08
90-day mRS scoreIn patients receiving EVT, the baseline NIHSS score increased and the probability of good functional outcome decreased (for every 1 point increase in the score, OR=.
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The guide recommends the interpretation of the "Experts Consensus on Brain Protection after Cardiac Arrest in China in 2020"-neurological evaluation
Time of Update: 2022-01-08
Please scan the QR code to download the APP directly Download link: Metz Medicine APP Tip: 78% of users have downloaded Metz Medicine APP , which is more convenient to read and communicate.
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Stroke: Removal of thrombus after stroke, collateral circulation suggests a better prognosis
Time of Update: 2022-01-08
Surprisingly, in the recent post-mortem analysis of the DEFUSE-3 trial (endovascular treatment after imaging evaluation of ischemic stroke), single-phase computed tomography (CT) angiography (CTA) was performed during the late treatment window after stroke Good collaterals are related to smaller ischemic core volume at baseline and reduced ischemic core growth, but not to better functional outcomes, the success of endovascular treatment, hemorrhagic complications, or death .
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Pain Pain Pain Pain...How to treat neuralgia after herpes zoster?
Time of Update: 2022-01-08
China’s " Consensus of Chinese Experts on Diagnosis and Treatment of Post-Herpes Zoster Neuralgia " clearly states that PHN is pain that lasts for 1 month or more after the rash has healed [3] .
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JAHA: Serum growth differentiation factor 15 levels are associated with post-ischemic stroke depression
Time of Update: 2022-01-08
Recently, the heart blood vessels published a research article on the disease areas authoritative magazine JAHA, the purpose of this study was to investigate the correlation between serum levels of GDF 15-PSD patients with ischemic stroke .
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Mov Disord: DTI study found that free water in the dorsal medial nucleus of the thalamus is associated with cognitive decline in Parkinson's disease
Time of Update: 2022-01-08
Mov DisordThis study assessed whether the FW of the thalamus is mainly involved in cognitive functions (ie, the dorsal medial nucleus and pronucleus), whether Meynert basal nucleus (nbM) and the hippocampus are associated with longitudinal cognitive decline, and distinguished the baseline cognition of patients with early Parkinson's disease Status .
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Neurology: Eat more flavonoids, healthy and longevity without dementia!
Time of Update: 2022-01-08
In order to prospectively study the relationship between long-term dietary flavonoids and subjective cognitive decline (SCD), experts from Harvard University and Zhejiang University have carried out related studies, and the results have been published in the journal Neurology .
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Neurology: People with the following characteristics pay attention-the pre-dementia progression may increase!
Time of Update: 2022-01-08
In order to study sociodemographic and medical predictors of MCI events and the subsequent MCI process, including continuous MCI diagnosis, cognitive normal classification and the development of dementia, from Columbia University, Alzheimer's disease and brain aging Experts from the institute carried out relevant research and the results were published in the journal Neurology .
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Ischemic stroke, it turns out that atrial fibrillation is also one of the culprits
Time of Update: 2022-01-08
So far, a large number of evidence-based medicine studies have shown that oral anticoagulants can effectively reduce the risk of stroke in 2/3 of patients with atrial fibrillation, and have been recommended by domestic and foreign guidelines .
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Pfizer's DMD gene therapy fordadistrogene movaparvovec was shelved by the FDA after the patient died
Time of Update: 2022-01-08
After the death of one patient in the Phase Ib study, the FDA shelved the clinical trial of Pfizer's Duchenne Muscular Dystrophy (DMD) drug candidate fordadistrogene movaparvovec .
com/story/5466389 https://firstwordpharma.
com/story/5466389 https://firstwordpharma.
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Stroke: hypotension after stroke, or increase the risk of death
Time of Update: 2022-01-08
Prevent cardiovascular eventsThe results of post-mortem analysis of clinical trials and observational studies indicate that low SBP (<120mmHg) may be harmful to the outcome (including mortality) of ischemic stroke .
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Front.aging-neurosci-FGF21 regulates microglia polarization and attenuates neurodegeneration in mice and cell models of Parkinson’s disease
Time of Update: 2022-01-08
FGF21 inhibits MPTP-injured NF-κB pathway in mice and enhances M2 microglia polarizationFGF21 significantly reduced the gene expression of M1 microglia markers IL-1β, TNF-α and CD 68 (Figure 2A) .
In summary, in this study, the authors showed for the first time that FGF21 significantly reduced MPTP-induced motor symptoms and cognitive dysfunction in mice .
