Pain Pain Pain Pain...How to treat neuralgia after herpes zoster?

Herpes zoster is an infectious skin disease caused by the reactivation of varicella-zoster virus (VZV) that is latent in the spinal dorsal root ganglia or cranial ganglia for a long time [1]
.

In addition to skin damage, the disease is often accompanied by neuropathic pain.

Herpes zoster is an infectious skin disease caused by the reactivation of varicella-zoster virus (VZV) that is latent in the spinal dorsal root ganglia or cranial ganglia for a long time [1]

Postherpetic neuralgia (PHN) is the most common chronic complication of herpes zoster, and it is also the most common type of post-infection neuralgia
.

PHN is usually defined as pain that lasts at least 1 month or 3 months or 6 months after the appearance of the rash

Postherpetic neuralgia (PHN) is the most common chronic complication of herpes zoster, and it is also the most common type of post-infection neuralgia

The incidence of PHN accounts for 5% to 30% of herpes zoster patients, and there are about 4 million PHN patients in China
.

PHN is more common in elderly patients with weakened immune function.

The incidence of PHN accounts for 5% to 30% of herpes zoster patients, and there are about 4 million PHN patients in China

So, can PHN be cured completely? How to treat patients at different stages?

So, can PHN be cured completely? How to treat patients at different stages?

 

In general, PHN treatment should be combined treatment and comprehensive treatment.
It is necessary to evaluate the efficacy and safety risks, and at the same time start with a relatively small dose and gradually increase the dose as the principle
.

In addition, the purpose of treatment is to improve pain, improve sleep, and improve the quality of life

In general, PHN treatment should be combined treatment and comprehensive treatment.

1.

References: [1] Chinese expert consensus on herpes zoster[J].
Chinese Journal of Dermatology,2018,51(6):403-406 [2] PréaudE,UhartM,BöhmK, et al.
Cost-effectiveness analysis of a vaccination program for the prevention of herpes zoster and post-herpetic neuralgia in adults aged 50 and over in Germany[J].
Hum Vaccin Immunother, 2015,11(4):884-896.
doi: 10.
1080/21645515.
2015.
1011561.
[3] Expert group for the compilation of consensus on diagnosis and treatment of postherpetic neuralgia.
Chinese expert consensus on diagnosis and treatment of postherpetic neuralgia[J].
Chinese Journal of Pain Medicine, 2016,22(3):161-167.
doi: 10.
3969/j.
issn.
1006-9852.
2016.
03.
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[4] PellissierJM,BrissonM,LevinMJ.
Evaluation of the cost-effectiveness in the United States of a vaccine to prevent herpes zoster and postherpetic neuralgia in older adults[J].
Vaccine,2007,25(49) :8326-8337.
doi: 10.
1016/j.
vaccine.
2007.
09.
066.
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