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New peptides with potential beyond existing anti-cancer drugs
Time of Update: 2023-02-03
The cyclic peptides recently discovered by the researchers have the ability to specifically bind to ubiquitin protein chains, which are often used as "death tags" for damaged proteins.
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Chinese scholars have made progress in analyzing the novel structure and mechanical properties of natural materials
Time of Update: 2023-02-03
Figure 1 Ginkgo husk is assembled from stone cells interlocking through "striated holes" Fig. 2 The unique stone cell "interlock" structure of ginkgo husk gives it excellent specific fracture toughne
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"PNAS" artificial retinal cells successfully connected to the eye! Unlock a host of new treatments for eye diseases
Time of Update: 2023-02-03
” David Gamm in his labAccording to a new study, retinal cells grown from stem cells can reach out to connect with neighbors, completing a "handshake," which could indicate that the cells are ready for trials in patients with degenerative eye disease.
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New progress has been made in analyzing the spatial and temporal differences of estuarine fish communities based on environmental DNA technology
Time of Update: 2023-02-03
Recently, the investigation and assessment team of the South China Sea Fishery Resources Investigation and Assessment Team of the South China Sea Fisheries Research Institute of the Chinese Academy o
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To infect the brain, the fungus learns to make itself smaller in guano!
Time of Update: 2023-02-03
Figure 3 Macrophage recognition of mannose helps small ex vivo cells to be uptaken by organs (Source: [1])03 One side of soil and water culture and one side of "bacteria": the pigeon fecal environment enhances the organ entry ability of Cryptococcus neoformansThe results of the venous transmission model showed that cell size was not the only factor affecting the rate of diffusion, and that the culture conditions of the fungus also greatly influenced the distribution in the organ.
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Nature Immunology: Cytokines secreted by T cells
Time of Update: 2023-02-03
Human Th17 cells engage gasdermin E pores to release IL-1α upon NLRP3 inflammasome activation "We don't know how IL-1α is made in T cells and how it is released from the cell," said first author Chao Ying-Yin. The research was part of her doctoral dissertation, and she now works at an international biotech company in Munich, Germany, developing T-cell therapies.
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The Sci Transl Med Lanke/Xu Ke team traced the evolution of the virus lineage and proposed a new strategy for the design of a broad-spectrum new crown vaccine
Time of Update: 2023-02-03
The epidemic caused by the new coronavirus (SARS-CoV-2) is still ongoing, and so far more than 640 million people have been infected with the new coronavirus and more than 6. 6 million people have d
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Cancer Res: Unravel the mystery of cancer's origins
Time of Update: 2023-02-03
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
essayGenetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms Is knowing where your ancestors came from the key to better cancer treatment?
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Chinese scholars have made progress in the research of distributed source coding
Time of Update: 2023-02-03
Fig. 1 Schematic diagram of the comparison of traditional source coding and distributed source coding principles: (A) traditional source coding (symmetrical); (B) distributed source coding (symmetric
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Brain metastases in melanoma patients, deciphering important molecular mechanisms
Time of Update: 2023-02-03
Different cell states determine the progression of the diseaseThe study's last author, Torben Redmer from the Institute of Medical Biochemistry and Pathology in Vetmeduni, summed up the main findings: "Our study provides evidence that MBMs can be divided into at least two subgroups.
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Eye tracking in visual challenges reveals neural coding
Time of Update: 2023-02-03
Instead, human vision is an active process that includes interactions between external objects and eye movements," Ahissar said.
Instead, human vision is an active process that includes interactions between external objects and eye movements," Ahissar said.
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Nature solves decades of puzzle: the original p53 was destroyed in a completely new way
Time of Update: 2023-02-03
Article BRD8 maintains glioblastoma by epigenetic reprogramming of the P53 network Image: Mills Lab weathered rain erosion during the Darlene Capone Brain Tumor Foundation's second annual walk to support glioblastoma research.
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Antibiotic residues in water pose a threat to human health
Time of Update: 2023-02-03
According to a comprehensive analysis published in The Lancet Planetary Health by the Karolinska Institute, antibiotic residues in wastewater and sewage treatment plants in surrounding areas of China and India may contribute to antibiotic resistance, and drinking water may pose a threat to human health.
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Nature: The key to the transformation of chronic blood cancers into aggressive diseases
Time of Update: 2023-02-03
The researchers also tested a drug compound that inhibits DUSP6 and found that this compound (used only in animal studies) prevented the progression of chronic disease to aggressive disease in two different mouse models of cancer and in mice with human tumors sampled from patients.
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The Lancet Microbe: A simple nasal swab can provide early warning of emerging viruses
Time of Update: 2023-02-03
Nasal host response-based screening for undiagnosed respiratory viruses: a pathogen surveillance and detection study As the COVID-19 pandemic has shown, potentially dangerous new viruses can begin to circulate among populations before they are detected by global public health surveillance systems.
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Fan Tianyuan's team from the School of Pharmacy won the AAPS Award for Pharmacy
Time of Update: 2023-02-03
Department of Pharmacy In October, the 2022 American Association of Pharmaceutical Sciences (AAPS) Annual Meeting was held in Boston, with universities, scientific research institutions and enterprises from many countries around the world More than 4,000 experts and scholars attended the conference.
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Alzheimer's disease: a gene associated with immune cells in the brain
Time of Update: 2023-02-03
Researchers at Indiana University School of Medicine are studying how to reduce a genetic variant found in brain immune cells that reduces the risk of late-onset Alzheimer's disease.
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Chinese scholars have made progress in remodeling antibody characteristics in immunotherapy
Time of Update: 2023-02-03
Figure Immune checkpoint blocking therapy remodeling antibody characteristics induces tumor immune evasion With the funding of the National Natural Science Foundation of China (grant numbers: 82025016, 31830025 and 81901585), Professor Kwong Dongming's team of Sun Yat-sen University has made progress in remodeling antibody characteristics in immunotherapy 。 The findings are based on "Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular.
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University of Hong Kong: Timely booster vaccination reduces omicron breakout infections and COVID-19 severity
Time of Update: 2023-02-03
Source: The University of Hong KongResearchers from the AIDS Institute of the Department of Microbiology, The University of Hong Kong's School of Clinical Medicine and the State Key Laboratory of Emerging Infectious Diseases found that timely vaccination with coronavirus vaccine, or BNT162b2 vaccine, is critical for inducing activation of virus-specific memory B cells and omicron cross-reactive T cell responses, significantly reducing the frequency and severity of breakthrough infections.
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eLife: How humans lose body hair
Time of Update: 2023-02-03
Image: An unprecedented study comparing the genomes of 62 mammalian species answers a question about the fundamental mechanism that forms human characteristics: scarcity of body hair.
Image: An unprecedented study comparing the genomes of 62 mammalian species answers a question about the fundamental mechanism that forms human characteristics: scarcity of body hair.
