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Chinese scholars have made progress in the research of addiction memory mechanism
Time of Update: 2023-02-03
Figure Addiction cues regulate the dynamic reshaping mechanism of synaptic memory in addiction With the support of the National Natural Science Foundation of China (grant number: 81822017, 82101565), the team of Professor Yuan Yifei of the Shanghai Mental Health Center (National Center for Mental Illness) made progress in the study of the mechanism of addictive memory, and the research results were based on "Retrieval-extinction of drug memory requires AMPA receptor.
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Chengdu Biotech Institute has made new progress in the research of heteroautotrophic coupled nitrogen removal in the high ammonia nitrogen load leachate system
Time of Update: 2023-02-03
8;font-family:;font-size:12pt;} The short-range nitrification-denitrification process refers to the inhibition or elimination of nitrite oxidizing bacteria in the system, so that the conversion of nitrogen is limited to the oxidation ofNH4+ to NO2-, In addition, NO2- is reduced to N2, eliminating the nitrate conversion step and saving the amount of aeration and carbon source addition in the system.
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Nature Genetics international large-scale research has revealed dozens of new genes linked to heart disease
Time of Update: 2023-02-03
Most of the new genomic loci were associated with very small changes in CAD risk, suggesting that few, if any, common genetic variants that had a significant impact on CAD risk by studying people of predominantly European ancestry were yet to be discovered, and to improve their discovery power, the researchers combined their large dataset with data from tens of thousands of individuals of East Asian descent from the Japan Biobank, including 29,000 CAD patients.
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The Lancet Psychiatry: During the pandemic, 1 in 5 healthcare workers in the UK had mental health problems
Time of Update: 2023-02-03
Previous studies have shown that the prevalence of anxiety and depression among healthcare workers during the pandemic ranged from 9 to 90 percent and 5 to 65 percent, respectively, and the prevalence of post-traumatic stress disorder (PTSD) ranged from 7 to 37 percent [1].
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Alzheimer's disease: a gene associated with immune cells in the brain
Time of Update: 2023-02-03
Researchers at Indiana University School of Medicine are studying how to reduce a genetic variant found in brain immune cells that reduces the risk of late-onset Alzheimer's disease.
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Nature: Stimulation of the blue plakia nucleus in the brain is expected to improve the efficiency of cochlear implant users in restoring hearing
Time of Update: 2023-02-03
Lead author Dr. Erin Glennon of New York University School of Medicine said, "Our findings suggest that differences in neuroplasticity, particularly in certain parts of the brain, such as the blue spot, may help explain why some cochlear implant users improve hearing faster than others.
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Northerners published a series of review papers in Reports on Progress in Physics and Nature Reviews Materials
Time of Update: 2023-02-03
exciton effect, single-molecule vibration effect, single-molecule structure and orbital properties from the perspective of physics, and shows that single-molecule optoelectronic devices can provide a potential solution for the miniaturization and functionalization of silicon-based microelectronic circuits.
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Nature: After contracting the new coronavirus, has the body's response to other threats changed? It depends on the gender
Time of Update: 2023-02-03
In the study, a team led by Tsang, who at the time at the National Institute of Allergy and Infectious Diseases (NIAID), and his colleagues, including lead author Rachel Sparks, also from NIAID, systematically analyzed the immune response in healthy people who received the flu vaccine.
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Danger: Disruption of smell and viral inflammation are associated with accelerated onset of Alzheimer's disease
Time of Update: 2023-02-03
According to a new study by researchers at the University of Colorado's Ann Schutz School of Medicine, viruses may accelerate the onset of Alzheimer's disease by triggering inflammation and disrupting connections between the olfactory system that controls smell and parts of the brain related to memory and learning.
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Proc. Natl. Acad. Sci. U.S.A.: Development of new probe for mitochondrial multicolor STED imaging
Time of Update: 2023-02-03
published a research paper entitled "Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain" and was selected as the cover article 。 The study reported a mitochondrial crest dye PK Mito Orange (PKMO) suitable for STED nanomicroscopy with excellent photostability and significantly reduced phototoxicity, enabling long-term, super-resolution mitochondrial dynamic imaging in immortalized mammalian cell lines, primary cells, and tissues, 3D-STED imaging of individual mitochondria, and multicolor STED imaging (Figure 1).
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Nature Biotechnology: Prevents rejection of transplanted cells by tricking antibodies
Time of Update: 2023-02-03
A new approach could overcome the persistent barriers of cell transplantation and immunotherapyResearchers at the University of California, San Francisco, have developed a novel, potentially life-saving way to prevent antibodies from triggering immune rejection in engineered therapy cells and transplanted cells.
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The Sci Transl Med Lanke/Xu Ke team traced the evolution of the virus lineage and proposed a new strategy for the design of a broad-spectrum new crown vaccine
Time of Update: 2023-02-03
The epidemic caused by the new coronavirus (SARS-CoV-2) is still ongoing, and so far more than 640 million people have been infected with the new coronavirus and more than 6. 6 million people have d
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Professor Yimin Cui's team from the Department of Pharmaceutical Affairs Management and Clinical Pharmacy published a blockbuster review in the journal STTT, a sub-journal of Nature: Targeting Integrin Pathways: From Signaling Pathways to Therapeutic Strategies
Time of Update: 2023-02-03
On January 2, 2023, the team of Professor Cui Yimin from the Department of Pharmaceutical Affairs Management and Clinical Pharmacy of Peking University School of Pharmacy presented in the Signal Transduction and Targeted sub-journal Nature The journal Therapy (STTT, Q1, IF=38.
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New progress has been made in the study of the basic regulation and evolutionary pathways of the specific reproductive patterns of the main pathogen taxa of fungal meningitis
Time of Update: 2023-02-03
The research team of Wang Linqi, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, published an article entitled "Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen" in Nature Communications.
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Dual-acting macromolecules: new ideas for cancer drug design
Time of Update: 2023-02-03
A fundamental challenge in drug development is how to balance "optimizing the drug's match to the target" with "the drug's ability to cross the cell membrane and reach the target. " In traditional dr
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New progress has been made in the research on the anti-rust mechanism of coffee
Time of Update: 2023-02-03
Large-grain coffee transcript annotation (A) and single-copy gene-constructed coffee genus maximum likelihood tree (B) Coffee rust caused by Hemileia vastatrix is a devastating disease that has become an important crop protection problem restricting coffee production.
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The main pathogen taxa of fungal meningitis are endemic to the regulatory basis and evolutionary pathways of the main pathogen taxa
Time of Update: 2023-02-03
On December 24, 2022, the research team of Wang Linqi, State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, published an article entitled "Regulatory basis for reproductive flexibility in a meningitis-causing fungal pathogen" in Nature Communications.
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Nature: Potentially deadly infections lurk dangerous allies in our gut
Time of Update: 2023-02-03
"Original:Enterococci enhance Clostridioides difficile pathogenesis A new discovery by Dr. Jason Papin and his collaborators at the University of Virginia School of Medicine could help doctors identify patients with severe C.
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Science: How do glass frogs become transparent?
Time of Update: 2023-02-03
This work could lead to new research related to blood clots, as glass frogs pack and transport about 90 percent of their red blood cells to the liver each day, but somehow avoid the production of blood clots.
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Nature Metabolism: Mapping the mastoylation modification of liver cancer tissues
Time of Update: 2023-02-03
Lactate is the main product of glycolytic metabolism in mammals, and it is significantly increased in pathological states such as tumors, sepsis, and autoimmune diseases. Its biological function has