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Inventory 2022: The "inflection point" of life science research - AI intelligence, has it really appeared?
Time of Update: 2023-02-03
In 2021, artificial intelligence made headlines: Nature, Science published separate articles reporting AI models that can accurately predict protein structure, and at the end of the year, Science als
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Li Xinzheng's research group and collaborators have made new progress in the development of simulation methods for molecular cluster tunneling cleavage spectra
Time of Update: 2023-02-03
Professor Li Xinzheng's research group, from the Institute of Condensed Matter Physics and Materials Physics, the State Key Laboratory of Artificial Microstructure and Mesoscopic Physics, the Nanopho
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Why some people are unable to regain their sense of smell after getting COVID-19
Time of Update: 2023-02-03
"For the study, Goldstein and colleagues analyzed olfactory epithelial samples collected from 24 biopsies, including nine patients with long-term olfactory loss due to COVID-19.
"For the study, Goldstein and colleagues analyzed olfactory epithelial samples collected from 24 biopsies, including nine patients with long-term olfactory loss due to COVID-19.
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Aging Cell Stress accelerates retinal degeneration, similar to natural aging
Time of Update: 2023-02-03
A new study in mice by researchers at the University of California, Irvine (UCI) shows that stress, such as elevated intraocular intraocular pressure (IOP), causes epigenetic changes in retinal tissue that resemble natural aging.
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Multi-institutional collaboration to uncover the mysteries of senescent cells and their impact on aging and human health
Time of Update: 2023-02-03
The National Institutes of Health's SenNet consortium aims to map senescent cells throughout the human life cycle to understand physiological health.
The National Institutes of Health's SenNet consortium aims to map senescent cells throughout the human life cycle to understand physiological health.
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Nanjing Medical University, Chinese Academy of Sciences Nature issued a paper: novel ribosomes in spermatogenesis can produce sperm-specific proteome
Time of Update: 2023-02-03
On December 14, 2022, the team of Sha Jiahao and Guo Xuejiang of Nanjing Medical University and the team of Qin Yan of the Institute of Biophysics of the Chinese Academy of Sciences published the article "A male germ-cell-specific ribosome controls male fertility" in Nature, discovering a novel ribosome in spermatogenesisSTAbility to produce sperm-specific proteomes.
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Construction of ionizable iron nanoadjuvants for personalized tumor vaccine treatment
Time of Update: 2023-02-03
202209910(Contributed by: Yu Navy Research Group) Tumor vaccines represent a therapeutic method that can induce body-specific and persistent anti-tumor immune response, and have great prospects for improving clinical tumor treatment.
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There is a new method for molecular imaging detection of early gastric cancer
Time of Update: 2023-02-03
Recently, the reporter of Science and Technology Daily learned from the Xinqiao Hospital of the Army Military Medical University that Professor Yang Shiming of the Department of Gastroenterology of the hospital, the team of researcher Wang Lei of the National Center for Nanoscience and the team of academician Xing Mengqiu of the University of Manitoba in Canada designed and constructed a bipyrene-peptide nanoprobe, which effectively solved the problem of "difficult to distinguish" and "difficult to break" in early gastric cancer.
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Chenji Wang/Yao Li's team revealed the oncogenic mechanism by which SPOP gene mutations promote abnormal activation of the BRAF-dependent MAPK-ERK signaling pathway
Time of Update: 2023-02-03
Fig. 1: SPOP-mediated BRAF ubiquitination modification to regulate the pattern of MAPK-ERK signaling pathwayFeng Kai, a master's student in the School of Life Sciences (currently a doctoral student at the Institute of Phenotypic Group), and Qing Shi, a postdoctoral student, are co-first authors of the paper.
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Suborganelle localization, interaction, and viability fine-tuning patterns of the human complete set of mitochondrial aminoacyl-tRNA synthetases
Time of Update: 2023-02-03
TRS_Editor A{font-family:;font-size:12pt;}On December 12, the international academic journal Nucleic Acids Research published online the latest collaborative research results of Xiaolong Zhou's research group and Wang Enduo's research group of the Center for Excellence in Molecular Cell Science (Institute of Biochemistry and Cell Biology) of the Chinese Academy of Sciences, "RNA granule-clustered mitochondrial aminoacyl-tRNA synthetases form multiple.
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Cell sub-journal: Zhang Haojian's team revealed the dynamic changes of m6A modification and the regulatory role and mechanism of PRMT6 in acute myeloid leukemia
Time of Update: 2023-02-03
Acute myeloid leukemia (AML) is a class of malignant hematologic tumors caused by myeloid progenitor cell differentiation and malignant proliferation. The accumulation of genetic or epigenetic change
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Progress has been made in the study of the response of carbon dioxide emissions to warming in degraded peat bogs at Chengdu Biosite
Time of Update: 2023-02-03
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Current Biology: Exercise inhibits insulin production!
Time of Update: 2023-02-03
His team's long-term goal, he says, is to combine these two research questions: How does the brain control walking and other behaviors, and how does the nervous system ensure that energy balance is regulated accordingly?essayBehavioural state-dependent modulation of insulin-producing cells in Drosophila.
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STTT:BA.5 causes stronger damage to cardiomyocytes than BA.1, similar to Delta
Time of Update: 2023-02-03
5 variant is more replicable, produces a more contagious virus, can cause stronger cytopathic effects, and stops heart muscle cells beating faster, or similar to Delta.
5 variant is more replicable, produces a more contagious virus, can cause stronger cytopathic effects, and stops heart muscle cells beating faster, or similar to Delta.
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Measurement of 16-year biological aging and cognitive decline based on DNA methylation
Time of Update: 2023-02-03
”DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife Image: Figure 3.
”DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife Image: Figure 3.
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Yuan Jing's research group revealed the key molecules for malaria parasite morphological control and transmission of Anopheles malaria
Time of Update: 2023-02-03
On December 20, Yuan Jing's group published an online publication entitled "Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito" online in the journal Nature Communications Research papers.
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The flu vaccine can reduce stroke
Time of Update: 2023-02-03
Dr Michael Hill, a researcher at the Cumming Medical School (CSM) and principal investigator of the study, said: "We wanted to know if the vaccine had the same protective effect for those at risk of stroke.
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The global number of new crown sequelae is estimated to be nearly 145 million, and we must be vigilant against these "new crown sequelae" after "Yangkang"!
Time of Update: 2023-02-03
The results of the study showed that regardless of whether they were hospitalized or not, 45% of people who recovered from the new crown infection still had at least one persistent symptom during an average follow-up of 4 months, the most common symptoms being fatigue, sleep disturbance, pain/discomfort, and difficulty breathing.
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In real-world studies of 540,000 people, vaccines are more effective than antibodies produced by infection
Time of Update: 2023-02-03
In the study, researchers analyzed 540,000 participants aged 12-110 in the Indiana Patient Care Network (INPC) database between November 29, 2020 and February 9, 2022, 267847 of whom were vaccinated and the other half matched by the same number of COVID infections, comparing the effectiveness of vaccines with natural immunity in preventing all-cause death, hospitalizations, and emergency department visits.
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Real-time follow-up radiation therapy can guarantee safer and more effective cancer treatment
Time of Update: 2023-02-03
By capturing and amplifying the tiny sound waves produced when X-rays heat human tissue, medical professionals can map the radiation dose in the body, providing them with new data to guide treatment in real time.
