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A new method to measure the torsional stiffness of DNA
Time of Update: 2021-08-28
In "Twist Stiffness of Extended and Plectonemic DNA" published in Physical Review Letters on July 7, the researchers reported a method for measuring the torsional stiffness of DNA.
"We came up with a very clever way to measure the torsional stiffness of DNA," said senior author Michelle Wang .
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Nature discovered for the first time: Oxytocin is really amazing!
Time of Update: 2021-08-28
A new set of experiments led by researchers at New York University’s Grossman School of Medicine includes round-the-clock photography of female mice interacting with their newborns and unmated female mice .
The research team also tested the brain electrical activity of unmated female rats during this period and later when they themselves became mothers .
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Where is the treatment for peripheral T-cell lymphoma of BMS and Takeda?
Time of Update: 2021-08-28
Subsequently, BMS carried out a confirmatory phase III clinical trial to evaluate romidepsin+CHOP (Ro-CHOP) and CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) in the first-line treatment of PTCL The efficacy in patients, but did not reach the primary efficacy endpoint of progression-free survival .
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The bizarre hadrons accurately predicted by Professor Shilin Zhu’s group of the School of Physics in 2012 were discovered for the first time in experiments
Time of Update: 2021-08-28
9" >Recently, the CERN Large Hadron Collider Bottom Quark Detector (LHCb) experimental group announced at the European Physical Society’s High Energy Physics Conference (EPS-HEP) that it has detected two charm quarks, an anti-up quark and one Reverse the four-quark state TCC+ of the down quark, thus confirming the bicharm strange hadron state composed of DD* meson predicted in 2012 by Professor Shilin Zhu and collaborators of the School of Physics .
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Mustang Bio and Miaoyou Medical International reach a cooperation that is expected to break the bottleneck of cell therapy
Time of Update: 2021-08-28
This technology will be used to change the manufacturing method of chimeric antigen receptor T cell (CAR-T) therapy, and may be used as a "ready-to-use" therapy, which has the potential to be applied to any tumor target .
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Lu Yingli's team from Shanghai Jiaotong University publishes original clinical research results in international journals
Time of Update: 2021-08-28
The results show that long-term and frequent nightlife and work significantly increase the risk of atrial fibrillation and coronary heart disease, revealing that the rhythm of life disorder, especially nightlife and work, may be The new risk factors of atrial fibrillation and coronary heart disease provide important public health and clinical guidance for paying attention to and improving the cardiovascular health of the population .
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"Neurology" Can some diabetes drugs reduce the risk of Alzheimer's disease?
Time of Update: 2021-08-28
"Patients with diabetes have been shown to have a higher risk of Alzheimer's disease, possibly due to high blood sugar levels, which are related to the formation of amyloid beta protein in the brain," said study author Dr.
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Nature's breakthrough discovery: a unique new mechanism of human short intron splicing
Time of Update: 2021-08-28
SPF45 is a new type of essential splicing factor that acts on a subset of human short introns; a new study by researchers at Fujita Health University in Japan shows that the splicing mechanism involving this factor is different from the longer traditional splicing factor.
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Innovative antisense nucleotide therapy across the blood-brain barrier is expected to revolutionize the treatment of neurodegenerative diseases
Time of Update: 2021-08-28
A few days ago, researchers from Tokyo Medical and Dental University (TMDU), Ionis Pharmaceuticals, and Takeda Corporation have discovered a new method to deliver ASO subcutaneously or intravenously across the blood-brain barrier to the central nervous system .
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New tumor cell tracking system
Time of Update: 2021-08-28
A team of researchers at the University of Texas at Austin has developed a new method to label tumor cells to figure out how they have evolved and changed over time to resist cancer treatments .
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Nature Sub-Journal: Children's MISC complications may be caused by T cell failure
Time of Update: 2021-08-28
The team performed RNA sequencing on the blood of misc patients (and the control group) to discover disease-related genes "clustered in the co-expression module of CD56dimCD57+ natural killer (NK) cells and depleted CD8+ T cells .
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Contraceptive antibodies are here!
Time of Update: 2021-08-28
In a new study published in Science Translational Medicine on August 11, the research team introduced an antibody that recognizes human sperm-specific antigens that can bind to and capture over 99% of human sperm in the vagina of sheep .
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Cell Research: A new generation of high-efficiency, low-toxicity tumor-restricted IL-15 prodrugs
Time of Update: 2021-08-28
On August 10, 2021, " Cell Research " magazine published online a collaborative research paper "Tumor-conditional IL-15 pro-cytokine reactivates" by researcher Peng Hua from the Institute of Biophysics of the Chinese Academy of Sciences and Professor Fu Yangxin from the University of Texas Southwestern Medical Center.
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New technology identifies proteins in living brains
Time of Update: 2021-08-28
After verifying the technology using fluorescence and electron microscope imaging of the brain, the researchers found that their technology took a snapshot of all the proteins (or proteome) in living neurons, which could then be analyzed by mass spectrometry after death .
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Use MOA-seq to map maize genome regulation switch
Time of Update: 2021-08-28
In their proof-of-concept study using corn ears, they demonstrated that their experiment, using micrococcal nuclease (MNase) as a structural probe, can detect known transcription factor (TF) binding sites .
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Responding to Actively Receiving Vaccines from Different Technical Routes of Variant Strains
Time of Update: 2021-08-28
" In response to a question from a reporter from the Science and Technology Daily, the leader of the scientific research team involved in vaccine research and development gave the first chapter of "The Book", "The vaccine route that needs to be designed must take this step first .
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2021-8-12 recent news bulletin
Time of Update: 2021-08-28
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Coronavirus is circulating in common American deerOne-third of white-tailed deer (Odocoileus virginianus) in the northeastern United States have antibodies against SARS-CoV-2, which indicates that they have been infected with the virus .
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Nature Sub-Journal: DNA-based data structure system
Time of Update: 2021-08-28
The team, led by researchers from the School of Computer Science at Newcastle University, has created a new dynamic DNA data structure that can store and recall information from DNA molecules in an orderly manner .
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Targeting mitochondria is expected to treat obesity
Time of Update: 2021-08-28
Our research uses a small molecule to simultaneously reshape mitochondria in multiple tissues, reverse obesity and correct metabolic diseases, even if mice continue to eat an unhealthy diet," said UCI principal researcher, professor of development and cell biology, and senior author Aimee Edinger .
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Protect coral reefs more effectively from the effects of climate change
Time of Update: 2021-08-28
In contrast, the statically expressed genes of the corals show a fixed response from the central part of the Red Sea Regardless of the application of thermal stress, it provides "resistance" to high water temperatures, but at the expense of the ability to respond flexibly to further increases in temperature," Voolstra said .
