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A team of researchers at the University of Texas at Austin has developed a new method to label tumor cells to figure out how they have evolved and changed over time to resist cancer treatments
"This is a technology that allows you to recreate the evolutionary history of tumors," said Amy Brock, an associate professor in the Department of Biomedical Engineering at Cockrell College
Essentially, the ability to "label" nucleic acids (the genetic information of cells, such as RNA or DNA) to monitor them is not a completely new technology
Monitoring changes over time is the key to successful transfer of treatment
Brock said: "This is one of the reasons why cancer treatment is so challenging-we don't have a good way to predict in advance which cells will be sensitive to a certain drug and which cells will be resistant
CLL is a low-grade B-cell malignancy and is usually monitored for months or even years before active treatment is required
The team at the University of Texas at Austin is now using ClonMapper to study several different cancer types
Catherine Gutierrez, Aziz M.