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Nature: A breakthrough in plant breeding! Combine grafting with CRISPR tools
Time of Update: 2023-02-03
Scientists at the Max Planck Institute for Molecular Plant Physiology write in Nature Biotechnology that breakthroughs in the CRISPR tool, aka "gene scissors," are being used to edit plant genomes, marking a change in methodology.
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New Spaceomics Techniques: Exploring the Early Stages of Disease
Time of Update: 2023-02-03
Most illnesses are initially asymptomatic, and the affected person usually still feels good — symptoms haven't yet appeared, or are still too mild to be aware of. However, changes have taken place in
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Chinese scholars have made progress in remodeling antibody characteristics in immunotherapy
Time of Update: 2023-02-03
Figure Immune checkpoint blocking therapy remodeling antibody characteristics induces tumor immune evasion With the funding of the National Natural Science Foundation of China (grant numbers: 82025016, 31830025 and 81901585), Professor Kwong Dongming's team of Sun Yat-sen University has made progress in remodeling antibody characteristics in immunotherapy 。 The findings are based on "Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular.
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iScience: Genome sequencing of endangered sharks
Time of Update: 2023-02-03
Image: Scientists have sequenced the genomes of hammerhead sharks and shortfin mako sharks at the chromosomal level, showing that their populations declined more than 250,000 years ago.
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MIT research subverts cognition: "Memory" may not be in neurons, but between synapses!
Time of Update: 2023-02-03
The researchers correlated the output (activity at the top and decoder precision at the bottom) with real neural data (left column) and several working memory models (right column). Most similar to t
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Flu or cold? A home smart device can help you
Time of Update: 2023-02-03
"Our microresonators are about 100 times better than previous resonators used for longwave infrared spectroscopy," Dingding Ren said.
"Our microresonators are about 100 times better than previous resonators used for longwave infrared spectroscopy," Dingding Ren said.
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An enzyme that fights off viruses may also accelerate cancer evolution
Time of Update: 2023-02-03
In the new study, Dr. Faltas and his team, including first author Weisi Liu, PhD, postdoctoral research assistant, addressed the specific role of APOBEC3G in bladder cancer through direct causal experiments.
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Danger: Disruption of smell and viral inflammation are associated with accelerated onset of Alzheimer's disease
Time of Update: 2023-02-03
According to a new study by researchers at the University of Colorado's Ann Schutz School of Medicine, viruses may accelerate the onset of Alzheimer's disease by triggering inflammation and disrupting connections between the olfactory system that controls smell and parts of the brain related to memory and learning.
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Zoological Research Institute collaborates to reveal that the human genome archaea resurrection drives aging
Time of Update: 2023-02-03
The study systematically defined and revealed aging-i nduced r esurrection of endogenousretrov irus, AIR-ERV) can be used as the driving force and measurement marker of aging in cells, organs and even the body, providing a new theoretical basis for the programmatic, cascading amplification and interventionability of aging, and providing important clues and ideas for the scientific assessment and early warning of human aging, and the prevention and treatment of aging and aging-related diseases.
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New peptides with potential beyond existing anti-cancer drugs
Time of Update: 2023-02-03
The cyclic peptides recently discovered by the researchers have the ability to specifically bind to ubiquitin protein chains, which are often used as "death tags" for damaged proteins.
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Nature Medicine: During the first wave of Omicron, vaccination helped limit the spread of COVID-19
Time of Update: 2023-02-03
" Studies in California prisons have found that recent vaccinations and boosters have reduced contagiousness, but the risk of infection remains highAccording to researchers at the University of California, San Francisco who analyzed transmission between people living in the same cell, vaccination helped limit the spread of COVID-19 in California prisons during the first wave of Omicron.
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Nature sub-issue: A map distinguishes four subtypes of "post-SARS-CoV-2 infection"
Time of Update: 2023-02-03
Data-driven identification of post-acute SARS-CoV-2 infection subphenotypes Acute sequelae of SARS-CoV-2 infection (PASC) refer to a wide range of symptoms and signs that persist, worsen, or emerge after acute SARS-CoV-2 infection, also known as Long Covid.
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To infect the brain, the fungus learns to make itself smaller in guano!
Time of Update: 2023-02-03
Figure 3 Macrophage recognition of mannose helps small ex vivo cells to be uptaken by organs (Source: [1])03 One side of soil and water culture and one side of "bacteria": the pigeon fecal environment enhances the organ entry ability of Cryptococcus neoformansThe results of the venous transmission model showed that cell size was not the only factor affecting the rate of diffusion, and that the culture conditions of the fungus also greatly influenced the distribution in the organ.
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Antibiotic residues in water pose a threat to human health
Time of Update: 2023-02-03
According to a comprehensive analysis published in The Lancet Planetary Health by the Karolinska Institute, antibiotic residues in wastewater and sewage treatment plants in surrounding areas of China and India may contribute to antibiotic resistance, and drinking water may pose a threat to human health.
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Nature: The new crown can change the immune system, or cause an excessive immune response
Time of Update: 2023-02-03
The study showed that after infection with the new crown, even mild symptoms can change the immune status of men, making men respond more strongly to the flu vaccine, indicating that after infection, when faced with other viruses, men trigger a stronger inflammatory response, leading to more pronounced functional changes in the male immune system, even long after recovery.
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Ketamine has been found to increase brain noise
Time of Update: 2023-02-03
" An international team of researchers, including HSE University-perm senior researcher Sofya Kulikova, found that ketamine, acting as an NMDA receptor inhibitor, increases background noise in the brain, leading to higher entropy of afferent sensory signals and disrupting their transmission between the thalamus and cortex.
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The research of Professor Qian Feng's team of Shanghai Jiaotong University revealed a new mechanism of pneumonia caused by methicillus-resistant Staphylococcus aureus
Time of Update: 2023-02-03
On January 2, 2023, Professor Qian Feng's research group of the School of Pharmacy of Shanghai Jiao Tong University published a report entitled Staphylococcal virulence factor HlgB targets the endoplasmic-reticulum-resident E3 ubiquitin ligase AMFR to the top international academic journal Nature Microbiology (IF=30.
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The study revealed the important role of circadian clock genes in the flight and reproductive behavior of Oriental armyworms
Time of Update: 2023-02-03
Recently, the innovation team of food crop pest monitoring and control of the Institute of Plant Protection of the Chinese Academy of Agricultural Sciences published a paper entitled "The clock gene, period, influences migratory flight and reproduction of the oriental armyworm, Mythimna separata (Walker)" in Insect Science.
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Nature Metabolism: Mapping the mastoylation modification of liver cancer tissues
Time of Update: 2023-02-03
Lactate is the main product of glycolytic metabolism in mammals, and it is significantly increased in pathological states such as tumors, sepsis, and autoimmune diseases. Its biological function has
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NEJM heavy: The phase III clinical data of the domestic new crown drug VV116 was released, and the effect was not inferior to Paxlovid, and it was safer
Time of Update: 2023-02-03
This phase 3 randomized controlled trial comparing the effects of the domestic novel coronavirus drug VV116 with the Pfizer new crown drug Paxlovid head-to-head showed that VV116 was not inferior to Paxlovid in terms of time to sustained clinical recovery in adult patients with mild to moderate COVID-19 with high-risk factors (4 days vs.