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Researchers develop new methods to study neurodegenerative diseases
Time of Update: 2021-08-28
This new technology can simultaneously quantify the surface tension and viscosity or thickness of protein droplets, which will help scientists study how they change, paving the way for further understanding of the mechanisms of these diseases and the development of drug treatments .
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How did the snake's fangs come from?
Time of Update: 2021-08-28
Research led by Flinders University and South Australian Museum showed that the answer lies in the special microscopic characteristics of their teeth .
Our research answers this question and shows that normal snake fangs can easily become hypodermic syringes," Fu Said Dr.
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Nature Sub-Journal: Adoptive cell therapy plus checkpoint inhibitor shows promise in non-small cell lung cancer
Time of Update: 2021-08-28
The results of a phase 1 clinical trial that evaluated the checkpoint inhibitor nivolumab combined with tumor infiltrating lymphocyte (TIL) therapy initiated by the researchers were published in today's "Natural Medicine" journal .
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Navigating the corn maze: a "optical switch" technology for mapping the corn genome
Time of Update: 2021-08-28
Hank Bass, professor of biological sciences, said: “The understanding of genome structure should help focus genome editing and accelerate larger-scale applied research, such as guiding research in precision agriculture and medicine .
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Science Spatial Transcriptomics of Single-Cell Resolution Bacterial Populations
Time of Update: 2021-08-28
This article developed par-seqFISH (Parallel Sequential Fluorescence In Situ Hybridization), which is a high-throughput method that can capture the gene expression profile of individual bacteria while preserving their physical environment in a spatial structure environment .
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Nature Sub-Journal: Creating a National Atlas of Deadly Listeria
Time of Update: 2021-08-28
"The goal of this work is to systematically collect soil samples from all over the United States," Liao said, "and capture the large-scale spatial distribution, genomic diversity, and population structure of Listeria species in the natural environment .
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The Wang Linqi research group of the Institute of Microbiology was invited to publish a review paper on fungal quorum sensing in the Annual Review of Microbiology
Time of Update: 2021-08-28
The composition, function and mechanism of the quorum sensing system of a model fungus [such as virulence (Figure 2)], and the important biological processes that the fungal quorum sensing system participates in the regulation of fungi/eukaryotes .
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Duan Chengguo's research group reveals the epigenetic regulation mechanism of rice miRNA and pollen development
Time of Update: 2021-08-28
On July 21, 2021, the international academic journal New Phytologist published an online publication titled "Intragenic Heterochromatin-mediated Alternative Polyadenylation Modulates MiRNA and Pollen Development" by the Duan Chengguo research group from the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences and the Li Qingshun research group at Xiamen University.
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Chinese scholars report for the first time on precise and reversible fusion and split
Time of Update: 2021-08-28
The research team creatively used GO fiber's two-dimensional elementary structure and large-volume shrinkage dynamic changes, using GO fiber as a model to explore the necessary conditions for precise and reversible fusion and splitting .
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Reactivation of protective p53 anti-cancer target eIF4A3 debut
Time of Update: 2021-08-28
(Source: Science Advances)Studies have also shown that deletion of eIF4A3 disrupts the process of RiBi, thereby altering the production of proteins in cancer cells .
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Nature Genetics discovers a new genetic mutation that causes high blood pressure in pregnant women
Time of Update: 2021-08-28
Bartholomew's Hospital found that a pair of unique genetic mutations can cause sudden onset of high blood pressure in pregnant women .
Bartholomew’s Hospital has discovered many genetic variants that cause small adrenal nodules to produce high levels of aldosterone .
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CRISPR gene editing technology brings new insights into hypertrophic cardiomyopathy
Time of Update: 2021-08-28
A paper published in the Proceedings of the National Academy of Sciences (PNAS) and by Beth Pratt, Professor of Mechanical Engineering at the University of California, Santa Barbara and Director of the Campus Bioengineering Institute, describes the results of a complex long-term collaboration, including Stanford University researchers at the University of Washington and the University of Kentucky .
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Unraveling the genetic "treasure map" of chronic kidney disease
Time of Update: 2021-08-28
Existing genetic studies have identified about 300 regions related to kidney disease in the human genome, but these maps have not yet been able to determine specific genes, cell types, and mechanisms .
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Chinese scholars have made progress in the preparation of high-density "dynamic three-atom" cluster catalysts
Time of Update: 2021-08-28
Supported by the National Natural Science Foundation of China (approval numbers: 22025205, 21673215, 91645202, 91845203, 11621063 and 91945302), the research groups of the University of Science and Technology of China Lu Junling, Li Weixue, Wei Shiqiang and other research groups worked closely to successfully design a high-density Ni 1 Cu 2 dynamic three-atom new non-noble metal catalyst, and made important progress in the selective hydrogenation of acetylene and 1,3-butadiene in an olefin-rich atmosphere .
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Oregon, infected with the new crown virus, deploys National Guard to hospitals
Time of Update: 2021-08-28
Fitness and health: The governor of Oregon said she will deploy as many as 1,500 National Guard soldiers to hospitals across the state to support medical staff because of the rapid spread of COVID-19 in the delta mutant virus.
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Chinese scholars have made progress in the controllable synthesis of organic fluorine compounds
Time of Update: 2021-08-28
Figure 1 Continuous and controllable defluorination conversion based on the spin center transfer process With funding from the National Natural Science Foundation of China (project numbers: 21672195, 21702201, 21971226), Wang Yifeng's research team from the University of Science and Technology of China and Hefei National Research Center for Microscale Physical Science collaborated with the theoretical computational chemist K.
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C-to-G single-base editor based on deep learning algorithm to optimize sequence specificity
Time of Update: 2021-08-28
The research established the deep learning model algorithm CGBE-SMART , which can accurately predict new types Single-base editing efficiency and editing effects of OPTI-CGBEs .
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"Light Vaccine": Black Technology to Protect the National Olympics Corps' New Crown Zero Infection
Time of Update: 2021-08-28
In addition to the conventional anti-epidemic measures such as masks, disinfection equipment, and vaccines, behind the Chinese delegation there is a black technology called "light vaccine": a kind of anti-virus and bacteria and other microorganisms, especially against the new coronavirus, can achieve 99.
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Potential new therapy for dangerous middle-aged and elderly blood cancer
Time of Update: 2021-08-28
We have shown that the CDK4/6 inhibitor palbociclib combined with ruxolitinib can significantly inhibit myelofibrosis, indicating that this combination of drugs is possible It is an effective treatment strategy against this devastating blood disease .
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Jiao Yuling's research group and collaborators reveal the mechanism of plant single cell regeneration
Time of Update: 2021-08-28
Combining in vivo imaging results, single-cell transcriptome data, and single-cell nuclear transcriptome data, the researchers found that the process of protoplastization accompanied by cell wall digestion increased the random expression of genes at the genome-wide level .
