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C-to-G single-base editor based on deep learning algorithm to optimize sequence specificity

 Last Update: 2021-08-28
 Source: Internet
 Author: User

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dna mrna sequence

analytical technology

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Yidi Sun's research group and Erwei Zuo's research group first obtained OPTI-CGBEs that can perform high-efficiency C to G base transversion and high-fidelity by screening UNGs from different species , codon optimization, and whole-genome and transcriptome-wide sequencing .

Figure 1.

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