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Scientists have discovered a new gene that causes colon cancer
Time of Update: 2022-10-25
” Researchers at Mount Sinai Tisch Cancer Institute have discovered a new gene that is essential for colon cancer growth, and found that inflammation in the external environment around tumors can promote the growth of tumor cells.
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The remnants of ancient viruses in the human genome are active in normal tissues
Time of Update: 2022-10-25
The older HML-2 virus showed the highest expression levels in human tissues, which may indicate that the activity of younger, less degraded HERV fragments containing intact protein-coding sequences may be inhibited by cells to prevent the production of harmful viral proteins, the authors said.
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Liquid-liquid phase separation mediates the formation of herpesvirus assembly intervals
Time of Update: 2022-10-25
In summary, this study is the first to find that γ herpes virus forms a virus assembly interval through a liquid-liquid phase separation mechanism in the late stage of infection, in which the viral interstitial protein ORF52 plays a crucial role.
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Monkeypox virus was detected in the testicles of nonhuman primate survivors
Time of Update: 2022-10-25
Retrospective detection of monkeypox virus in the testes of nonhuman primate survivors Immunofluorescence staining shows that monkeypox virus (green) can be detected in the epididymal cavity (red) of crab-eating macaques infected with acute monkeypox infection, which is where sperm maturation and storage.
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Nature: Easily remove gels from mouse pancreatic cancer
Time of Update: 2022-10-25
”In the new paper, Schaal and his collaborators in Chilkoti's lab test the synergy of the new therapy with paclitaxel, a commonly used chemotherapy drug, to treat various mouse models of pancreatic cancer.
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Cancer Science: Drug properties that make cancer metastasis treatments more effective
Time of Update: 2022-10-25
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
The lymphatic drug delivery system (LDDS) is a promising therapeutic intervention for metastatic lymph nodes.
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Studies have found rice koji disease resistance genes
Time of Update: 2022-10-25
Before the 80s of the 20th century, rice koji disease occurred sporadically, and usually occurred in rice harvest years, so it was also called "abundant grain disease" by the folk. Before the 80s of
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Singaporean scientists report that a "high-sugar diet" slows down aging
Time of Update: 2022-10-25
Prolonged stress response leads to cell deathA day after feeding high-glucose food, Nanyang Technological University scientists monitored the activity of three pressure sensors, each responsible for a cellular pathway in the folding protein response.
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Weight changes in early Parkinson's may be related to changes in thinking skills
Time of Update: 2022-10-25
According to a study in the online journal, people who gained or lost weight shortly after being diagnosed with Parkinson's disease may be more likely to have changes in their thinking skills than those who maintain their weight.
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New research is an important step towards curing AIDS
Time of Update: 2022-10-25
Currently, antiretroviral therapy (ART) is mainly used to treat HIV and prevent the onset of AIDS, which suppresses the amount of virus in the blood and partially restores the immune system.
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The new research method sheds light on the changes that occur in our brains as we learn
Time of Update: 2022-10-25
Dr Hollis Klein, Professor Hahn of the Scripps Institute, chair of neuroscience and senior author of the new study, said: "We still don't understand all the underlying mechanisms of how brain cells respond to changes in response to experiences, but this approach provides a new window into our understanding of the process.
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Cell Discovery Gao Zhaobing's research group collaborated to reveal the molecular mechanism by which MLKL channels perform cell death and neuroinflammation
Time of Update: 2022-10-25
Recently, the research team of Gao Zhaobing, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, together with Dr. Wang Sheng of Fudan University, proved that PIP2 is an endogenous agonist of MLKL channels, and PIP2 enhances channel function and "ignites" MLKL-mediated procedural necrosis and inflammatory immune responses 。 The research results were published in the international journal Cell Discovery under the title "Enhanced channel activity by PI(4,5)P2 ignites MLKL-related pathogenic processes".
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Nature: The first induced pluripotent stem cell model for post-traumatic stress disorder
Time of Update: 2022-10-25
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression The skin cells were reprogrammed into induced pluripotent stem cells and then turned into neurons exposed to stress hormones, which were then observed by the team.
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Small pieces of resistance were found in pathogen diversity surveys
Time of Update: 2022-10-21
Pneumococcal within-host diversity during colonisation, transmission and treatment A new study from the Wellcome Sanger Institute, the University of Oxford, the Shocko Malaria Research Group and Imperial College London reveals the secret life of Streptococcus pneumoniae, which kills hundreds of thousands of babies every year.
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Cell large study: Cancer tumors contain a variety of fungi, each of which is different
Time of Update: 2022-10-20
Original:Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactionsThe list of products used in the article is as follows: According to a large study led by researchers at the Weizmann Institute of Science and the University of California, San Diego, cancer tumors contain a variety of fungi, each of which is differentThe study, published today in the journal Cell, could have implications for the diagnosis and treatment of cancer, as well as for detecting cancer through blood tests.
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By 2035, half of the world's coral reefs could face unsuitable environments
Time of Update: 2022-10-20
In a new study published Oct. 11, researchers at the University of Hawaii in the United States revealed that in a worst-case scenario, half of the world's coral reef ecosystems would be permanently exposed to unsuitable environments for just a dozen years.
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Huazhong University of Science and Technology has made important progress in the preparation technology of biomimetic underwater viscose for mussels
Time of Update: 2022-10-20
Professor Yan Yunjun's team is committed to the research and development of new bio-based underwater adhesion materials, and has made a series of important progress, and this study has successfully constructed an extracellular functionalization system for mussel mycin (Li et al.
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The first defense system discovered to guide jumping genes "Kipferl"
Time of Update: 2022-10-20
The piRNA pathway was first discovered in Drosophila melanogaster using a protein called "Rhino" to look for piRNA clusters in the genome.
The piRNA pathway was first discovered in Drosophila melanogaster using a protein called "Rhino" to look for piRNA clusters in the genome.
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Chinese scholars have made progress in the study of the mechanism of osteoporosis
Time of Update: 2022-10-20
Figure Diagram of the mode of action of skin keratinocytes secreting cystatin-A (Csta) in regulating bone metabolism With the support of the National Natural Science Foundation of China (grant numbers: 82172507, 81700783, 81991511), Huang Bin's team at Southern Medical University has made progress in the mechanism of osteoporosis 。 The research results, titled "Skin chronological aging drives age-related bone loss via secretion of cystatin-A," were published on October 6, 2022 in Nature In the journal Nature Aging.
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Nature sub-journal: Cell outpost for neutralizing hepatitis B virus
Time of Update: 2022-10-20
In 2016, a UNIGE team led by Associate Professor Michel Strubin of the Department of Microbiology and Molecular Medicine at the University of Michigan School of Medicine and the Geneva Center for Inflammation Research revealed a mechanism critical to understanding the disease: When our immune system defends itself, a protein complex called SMC5/6 — the interdependent group — present in our cells detects viral DNA 。 The virus then fights back, producing a special protein, protein X.