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Target Clock Protein! This breakthrough led to the development of glioblastoma drugs
Time of Update: 2022-09-30
Pictured: A new small molecule drug, the first to target circadian clock protein to treat glioblastoma, is currently in Phase I clinical trials.
Pictured: A new small molecule drug, the first to target circadian clock protein to treat glioblastoma, is currently in Phase I clinical trials.
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Ji Xiong's team in the School of Life Sciences revealed RNA polymerase II subunit heterogeneity and CTCF insulation mechanism
Time of Update: 2022-09-30
On September 15, 2022, the research group of researcher Ji Xiong of the School of Life Sciences of Peking University published a research paper entitled "Targeted protein degradation reveals RNA Pol I
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The team of Ma Jinbiao, Wang Hailin, Dong Aiwu and Shi Yang worked together to reveal the structure and function of Arabidopsis METTL4
Time of Update: 2022-09-30
The team of Ma Jinbiao, Wang Hailin, Dong Aiwu and Shi Yang worked together to reveal the structure and function of Arabidopsis METTL4 On September 26, 2022, the team of Professor Ma Jinbiao and Prof
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Chengdu Biotech has made progress in the screening of high-efficiency HN-AD strains and their enhanced deodorization applications
Time of Update: 2022-09-30
Bioresource Technology Links to the original article Figure 1 Univariate optimization of strain HY-1 withNH4+ as the nitrogen source NH4+ Figure 2 Univariate optimization and denitrification analysis of strain HY-1 under anaerobic conditions Figure 3 Nitrogen balance analysis of strain HY-1 under different conditions Figure 4 Deodorization application of strain HY-1 in BTF
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Using the new technology, researchers have made surprising discoveries about how the brain responds to taste
Time of Update: 2022-09-30
In a new study published in Contemporary Biology, researchers at Brown University describe how they developed a new imaging technique and used it to map the neural activity of fruit flies in response to sweet and bitter tastes.
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The "pharmaceutical factory" implant eradicated advanced tumors in mice
Time of Update: 2022-09-30
Image credit: Jeff Fitlow/Rice UniversityHOUSTON – (August 22, 2022) – Researchers at Rice University and Baylor School of Medicine have demonstrated that they can eradicate late-stage dermatoma tumors in mice in just a few days by combining treatment with Rice cytokine "drug factory" implants and checkpoint inhibitor drugs.
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Green tea improves intestinal health and lowers blood sugar
Time of Update: 2022-09-30
010“A Green Tea Extract-Rich Confection in Healthy and Metabolic Syndrome Adults Decreases Small Intestinal Permeability in Association With Lower Gut Inflammation” by Min Zeng, Joanna Hodges, Geoffrey Sasaki, Sisi Cao, Yael Vodovotz and Richard Bruno, 14 June 2022, Current Developments in Nutrition.
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eLife: When the mother turns off the father's genes in the embryo
Time of Update: 2022-09-30
”Article titled Polycomb protein-mediated paternal chromosomal inhibition maintains haploid doses of diploid embryos of makodoniumPolycomb-mediated repression of paternal chromosomes maintains haploid dosage in diploid embryos of Marchantia Picture: Chromosomes of a money embryo on a plate in the middle of cell division.
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Single-cell multi-omics analysis provides an in-depth analysis of the tumor microenvironment of pancreatic cancer
Time of Update: 2022-09-30
They paid particular attention to cells that express acinar markers, as one theory suggests that pancreatic ductal adenocarcinoma originates from acinar cells that undergo acinar-duct metaplasia (ADM).
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Nature Sub-Journal: How Inflammation Caused by Injury or Illness Recovers
Time of Update: 2022-09-30
The researchers defined common health trajectories based on how quickly white blood cells and platelets returned to normal after the inflammatory responseThis finding could help clinicians recognize and intervene more quickly when the recovery process is not going wellThe team's ultimate goal is to establish a personalized recovery trajectory that enables patients to recover from a wide variety of medical and surgical conditions and can be used in clinical settings.
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A special compound used to protect plants from predators can inhibit the growth of cancer cells
Time of Update: 2022-09-30
They then converted it into an active body containing a pyrrole structure near the cancer cells to reduce damage.
They then converted it into an active body containing a pyrrole structure near the cancer cells to reduce damage.
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Chemosphere School of Public Health Tian Ying and Gao Yu's team found that mothers were exposed to perfluorinated compounds during pregnancy...
Time of Update: 2022-09-30
The weight of each PFAS in the WQS model This study is the first prospective study to explore the relationship between maternal exposure to PFAS mixture during pregnancy and obesity in offspring children.
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Scientists have finally discovered the origin of chromatin as well as the mysterious ancestors of eukaryotes
Time of Update: 2022-09-30
References: A phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution In almost every human cell, a nucleus that is only one millionth of a meter wide must contain two meters of DNA.
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The Human Brain Project reveals the mechanisms of action of psychostimulants on attention and learning
Time of Update: 2022-09-30
Striatal dopamine dissociates methylphenidate effects on value-based versus surprise-based reversal learning Psychostimulants are often used to treat mental disorders or improve cognitive abilities, but the benefits of these drugs vary for everyone because their effects vary greatly between individuals and within the same patient.
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eLife: When the mother turns off the father's genes in the embryo
Time of Update: 2022-09-30
”Article titled Polycomb protein-mediated paternal chromosomal inhibition maintains haploid doses of diploid embryos of makodoniumPolycomb-mediated repression of paternal chromosomes maintains haploid dosage in diploid embryos of Marchantia Picture: Chromosomes of a money embryo on a plate in the middle of cell division.
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A new method for testing protein-based drugs
Time of Update: 2022-09-30
"The approach we developed at New Jersey Tech has the potential to have a significant impact on quantitative proteomics, and it represents a paradigm shift in the pharmaceutical industry in monitoring biopharmaceutical products and process impurities for quality control," said Hao Chen, the paper's corresponding author and professor in the Department of Chemical and Environmental Sciences at New Jersey Tech.
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The "pharmaceutical factory" implant eradicated advanced tumors in mice
Time of Update: 2022-09-30
Image credit: Jeff Fitlow/Rice UniversityHOUSTON – (August 22, 2022) – Researchers at Rice University and Baylor School of Medicine have demonstrated that they can eradicate late-stage dermatoma tumors in mice in just a few days by combining treatment with Rice cytokine "drug factory" implants and checkpoint inhibitor drugs.
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The high-temperature-resistant variety Cottonium 4302 cultivated by the subtropical ecology has achieved a bumper harvest
Time of Update: 2022-09-30
The Institute of Subtropical Agroecology of the Chinese Academy of Sciences passed the national examination in 2021 with a high yield, high-quality, multi-resistance new variety Kequanyou 4302 in Hubei this year to achieve a bumper harvest!
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New Quick Detection Platform: DNA Network
Time of Update: 2022-09-30
According to a new study, a small web woven by strands of DNA could trap the spike proteins of the virus that causes COVID-19, illuminate the virus, perform rapid but sensitive diagnostic tests, and also stop the virus from infecting cells, opening up a new possible avenue for antiviral therapy.
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Science provides "quality assurance" for new stem cells: macrophages are responsible for review
Time of Update: 2022-09-30
”Quality assurance of hematopoietic stem cells by macrophages determines stem cell clonality The top two images show a stressful stem cell, shown by the calreticulin (yellow spike) expressed on its surface, which is engulfed and engulfed by macrophages.
