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Perfluorine and polyfluoroalkyl substances (PFAS) are a class of man-made compounds with carbon-fluorine bonds, with hydrophobic and oleophobic properties, commonly used in consumer products and industrial production processes
.
Epidemiological and toxicological studies have shown that exposure to environmental endocrine disruptors early in life may be associated with obesity in childhood or adulthood, and these endocrine disruptors are known as "fattening factors.
Tian Ying and Gao Yu's research group at the School of Public Health, Shanghai Jiao Tong University School of Medicine, published a paper entitled "Prenatal exposure to per- and polyfluoroalkyl substances and childhood adiposity at 7 years of age" in Chemosphere Vol.
This study was based on children in the Laizhou Wan Birth Cohort (LWBC) established in the Laizhou Bay area of Shandong Province, with a total of 206 mother-child pairs
included.
Linear regression analysis of single contaminants found that PFHpA and PFOSA were negatively correlated
with childhood obesity indicators in all children.
The weight of each PFAS in the WQS model
This study is the first prospective study to explore the relationship between maternal exposure to PFAS mixture during pregnancy and obesity in offspring children
.
Zhang Shanyu, a 2020 doctoral candidate at the School of Public Health of Shanghai Jiao Tong University School of Medicine, is the first author, and Professor Tian Ying and Assistant Researcher Lei Xiaoning of the School of Public Health of Shanghai Jiao Tong University School of Medicine are the co-corresponding authors
of the paper.
