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Poor heart health predicts premature brain aging
Time of Update: 2022-09-29
”The researchers used established MRI-based machine learning models to estimate the brain age of members of the Insight 46 study, funded by the Alzheimer's Research Uk and led by Professor Schott.
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The role of dementia proteins in normal memory
Time of Update: 2022-09-29
Article titleTau protein target recognition reveals the dependent role of NSF on AMPA receptor transport and memory formation New research reveals how tau proteins, a key element in the formation of Alzheimer's disease, are involved in the normal learning process of a healthy brain — which could provide a focal point for future drug therapies.
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mSystems: Promotes nutritional interactions in periodontitis
Time of Update: 2022-09-29
Nucleatum produces polyamines such as putrescine and cadaveric amines through metabolic cross-feeding with other symbiotic bacteria," said corresponding author Dr. Masae Kuboniwa.
Nucleatum produces polyamines such as putrescine and cadaveric amines through metabolic cross-feeding with other symbiotic bacteria," said corresponding author Dr. Masae Kuboniwa.
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Two papers in the Journal of Nature and Aging Cell: How Mitochondrial Dysfunction Contributes to Premature Aging and Disease
Time of Update: 2022-09-29
Article titlePremature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Polg mutator mouse Researchers at the University of Buffalo and their collaborators have developed powerful new ways to study and possibly reverse the cellular mechanisms that cause mitochondrial disease and premature aging.
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Ancient tooth DNA reveals the evolution of the "cold sore" herpes virus
Time of Update: 2022-09-29
In theory, Sikora said, researchers could perform DNA sequencing on pathogens that infect older humans and animals, which could have lived 1 million years ago.
In theory, Sikora said, researchers could perform DNA sequencing on pathogens that infect older humans and animals, which could have lived 1 million years ago.
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Nature Plants reveals the molecular mechanisms by which plants select partners for different MYB and bHLH transcription factors to form complexes
Time of Update: 2022-09-28
On August 22, 2022, the School of Life Sciences of Fudan University and the State Key Laboratory of Genetic Engineering Dong Aiwu, Gan Jianhua and Huang Jianxun collaborated to publish a research pap
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Chinese scholars have made progress in the research of extreme thermal insulation materials for ceramic aerogels
Time of Update: 2022-09-28
Figure Semicrystalline double-zero ceramic aerogel superelastic and high temperature insulation performance With the support of the National Natural Science Foundation of China (approval number: 51921006, 51878227), the team of Professor Li Hui and Professor Xu Xiang of Harbin Institute of Technology and collaborators have made progress in the research of ceramic aerogel extreme insulation materials, and the relevant results have been "Hypocrystalline ceramic aerogels for thermal insulation at extreme.
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Biopic Tang's team and collaborators found that mixed-lineage tumor cells are widespread in patients with non-small cell lung cancer and revealed their biological characteristics
Time of Update: 2022-09-28
Lung cancer is one of the most morbid and mortal malignancies in the world, with about 1. 8 million people dying from lung cancer worldwide in 2020 [1]. From the histopathology, lung cancer is mainly
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Huang Qiang's research group studied a new method for de novo design of nucleic acid aptamers
Time of Update: 2022-09-28
Recently, Biosensors & Bioelectronics, an authoritative academic journal in the field of biosensors, published a research paper on nucleic acid aptamer molecular design by Professor Huang Qiang's res
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Neurology review of academician Lu Lin's research group of the sixth academy of Peking University revealed that leisure activities are related to a reduced risk of dementia
Time of Update: 2022-09-28
On August 10, 2022, academician Lu Lin, president of peking university sixth hospital, published a research paper entitled "Leisure Activities and the Risk of Dementia: A Systematic Review and Meta-Analysis" at Neurology.
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Niche differentiation in the multi-trait dimension maintains closely related tree species in tropical forests...
Time of Update: 2022-09-28
Studies have confirmed that resource acquisition, photosynthetic ability, water use and transport traits, and defense traits are independent trait dimensions; Second, compared with several other traits, the defensive traits of Euphorbiaceae do not have phylogenetic signals and are non-conserved evolution in the community; Plant-eating insects promote the differentiation of secondary metabolites from the leaves of Euphorbiaceae species, thereby promoting the coexistence of closely related tree species at small scales.
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Science Bulletin published a team article by Professor Jin Hongfang Du Junbao of Peking University Hospital online How to distinguish between vasovagal syncope and psychosocuous pseudosynosis in children?
Time of Update: 2022-09-28
Recently, Professor Jin Hongfang and Professor Du Junbao's team from the Department of Pediatrics of Peking University First Hospital published an online publication entitled "Vasovagal syncope or psychogenic pseudosyncope?" in science bulletin (impact factor 20.
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The Zhang Hongquan/Zhan Jun team discovered a new mechanism for the AMPK-HOXB9-KRAS axis to sense cellular energy changes to regulate the progression of lung adenocarcinoma
Time of Update: 2022-09-28
The mortality rate caused by lung cancer is the highest of all malignant tumors, which seriously affects human survival and health. A century ago, German scientist Warburg observed the characteristic
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Lin Aifu's research group of the Chinese Academy of Biological Sciences published a paper in Nature Metabolism to reveal RNA-mediated organelles...
Time of Update: 2022-09-27
Figure 1 Cholesterol regulates SNHG6-FAF2-mTOR signaling complex assembly in the organelle interaction regionFurther, the authors used a cholesterol-induced naflD-HCC mouse model to confirm the regulatory role of SNHG6 in the dynamic evolution of tumors, and found that overexpression of SNHG6 in mouse livers will promote the activation of the cholesterol-induced mTORC1 signaling pathway and accelerate the malignant lesion process from non-alcoholic fatty liver to liver cancer in mouse livers.
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Professor Xia Ningshao's team has revealed a new mechanism of antibody cocktail therapy
Time of Update: 2022-09-27
Antibody therapy is an important means of prevention and treatment of infectious diseases, antibody cocktail therapy is considered to be a more effective treatment than monotherapy, usually has the ad
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The team of Aiwu Dong, Jianhua Gan, and Jianxun Huang collaborated to reveal the molecular mechanism by which different MYB and bHLH transcription factors in plants select partners to form complexes
Time of Update: 2022-09-27
Aiwu Dong, Jianhua Gan, and Jianxun Huang teamed up to reveal different MYB and bHLH transcription factors in plantsMolecular mechanisms by which select partners form complexesOn August 22, 2022, aiwu Dong, Jianhua Gan and Jianxun Huang of the School of Life Sciences of Fudan University collaborated to publish a research paper entitled "Structural insights into partner selection for MYB and bHLH transcription factor complexes" online in nature plants journal.
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The role of DNA methylation in regulating the development and maturation of fruits
Time of Update: 2022-09-27
Transcriptional levels of ripening-related genes in tomato fruit were studied by transcriptome sequencing, and the expression of multiple mature-related genes such as PE1, PG2, and LOXB in the CR-08 mutant line was upregulated.
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Stone Age surgery: the earliest evidence of amputation found
Time of Update: 2022-09-21
" The findings, published in the journal Nature, describe the skeletal remains of a young adult found in a cave in Borneo, East Kalimantan, where at least 31,000 years ago — whose left calf and part of his left foot were amputated, possibly in childhood, and the patient survived the operation, surviving at least 6 to 9 years.
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Cell Sub-Journal: Bird neurons use three times less glucose than mammalian neurons
Time of Update: 2022-09-21
This means that neurons in the bird brains consume on average three times less glucose than mammalian brains.
This means that neurons in the bird brains consume on average three times less glucose than mammalian brains.
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Nature's mechanism for extending lifespan through the self-help "recycling system" of cells
Time of Update: 2022-09-21
"Lysosomal damage is a marker of aging and many diseases, particularly neurodegenerative diseases such as Alzheimer's," said lead author Jay Xiaojun Tan, Ph. D.
Nature, 2022 "Lysosomal damage is a marker of aging and many diseases, particularly neurodegenerative diseases such as Alzheimer's," said lead author Jay Xiaojun Tan, Ph. D.
