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Photodynamic drugs antitumor stem cell and ribosomal inhibition
Time of Update: 2022-10-02
Ribosomes in each mammal copy number is tens of millions, accounting for about 10% of the total copy number of proteins in the cell, 85% of the total RNA, consuming more than 50% of the total ATP of
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JMC: A novel strategy for intestinal targeted FXR antagonists in the treatment of NASH
Time of Update: 2022-10-02
(Contributed by Nan Fajun Research Group, Xie Cen Research Group) Nonalcoholic steatohepatitis (NASH) is a clinicopathological syndrome in which lipid accumulation, inflammation, and fibrosis of the liver are externally manifested by multiple risk factors, multiple cell types, and multiple tissues and organs.
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New research has found a link between diabetes and urinary tract infections
Time of Update: 2022-10-02
"People with diabetes have lower levels of psoriasis, which weakens the protective barrier function of cells and increases the risk of bladder infection.
"People with diabetes have lower levels of psoriasis, which weakens the protective barrier function of cells and increases the risk of bladder infection.
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A new method of treating gum disease – topical gels
Time of Update: 2022-10-02
A new study led by researchers at the New York University School of Dentistry suggests that a topical gel can block a receptor of a metabolic byproduct called succinate, treating gum disease by inhibiting inflammation and altering the composition of oral bacteria.
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Coffee and cigarettes: New research reveals an unexpected connection
Time of Update: 2022-10-02
Reference: Coffee and cigarettes: Modulation of high and low sensitivity α4β2 nicotinic acetylcholine receptors by n-MP, a biomarker of coffee consumption The findings provide a solid basis for further research into nicotine withdrawal behavior.
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The researchers developed a new method for image denoising
Time of Update: 2022-10-02
In fact, the technology could soon be applied to high-quality graphics rendering in video games, augmented reality, virtual reality, and metaverses!essaySelf-Supervised Post-Correction for Monte Carlo Denoising Researchers from Gwangju Institute of Science and Technology in South Korea, the VinAI Institute in Vietnam, and the University of Waterloo in Canada have proposed a new way to improve the visual quality of path tracking using post-correction networks and self-supervised machine learning frameworks.
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Spatial variation in ant-tree binary networks is driven by bottom-up processes
Time of Update: 2022-10-02
Oecophylla smaragdinaCrematogaster The article was published in the journal Ecological Entomology, a journal of the Royal Entomological Society, under the title Spatial Variation in ant–tree bipartite networks is driven by a bottom-up process.
Spatial Variation in ant–tree bipartite networks is driven by a bottom-up process Figure 1: Ant-tree binary network in Xishuangbanna 5 plots.
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COVID-19 can disrupt the placenta's immune response
Time of Update: 2022-10-02
Dr. Christina Adams Waldorf, Professor of Obstetrics and Gynecology at the University of Washington School of Medicine, said: "This is the largest study to date on the placenta of a woman infected with COVID-19 during pregnancy.
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Molecular mechanisms leading to Zika virus-associated microcephaly
Time of Update: 2022-10-02
"When oligodendrocytes do not mature properly, the formation of the myelin sheath may be defective, which has very adverse consequences for brain development," said Daniel Martin-de Suza, the last author of the article and a professor at the Institute of Biology at Campinas State University (IBB-Unicamp).
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Li Jinsong Cell Res constructs a mouse model of chromosome fusion and simulates the evolution process of chromosomes
Time of Update: 2022-10-02
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A potential new weapon in the fight against bladder cancer
Time of Update: 2022-10-02
The researchers showed that a cancer-seeking molecule called pHLIP, in combination with an FDA-approved fluorescent dye called ICG, could successfully target tumors in the human bladder, illuminating cancerous foci and making it easier for surgeons to see and remove them.
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Gao Peng's research group and collaborators in the School of Physics revealed the topological phase transition process of polar sigmon at the atomic scale
Time of Update: 2022-10-02
Recently, Professor Gao Peng's research group of the Center for Quantum Materials Science of the School of Physics of Peking University and the Electron Microscopy Laboratory has realized the observat
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Professor Chen Mingzhou's research group has made new progress in the study of the mechanism of host protein regulation of HPIV3 replication
Time of Update: 2022-10-02
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Dozens of genetic defects that are important for immune defense
Time of Update: 2022-10-02
Researchers from the University of Helsinki's Institute of Biotechnology pioneered the discovery of the first patient NFKB1 gene mutation, and they worked with international clinicians to identify and characterize a large number of unreported NFKB1 variants in patients with immune system-related diseases.
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Cell Reports: How cells remove garbage
Time of Update: 2022-10-02
essayIdentification of CUL4A- DDB1-WDFY1 as the E3 ubiquitin ligase complex to initiate lysophagy Figure: A lysosomal is an acidic intracellular organelle that is essential for the degradation of various cellular components.
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What does it mean when the circadian lipid rhythm goes wrong?
Time of Update: 2022-10-02
"We have long known that disorders of the biological clock are closely linked to metabolic diseases, such as type 2 diabetes, which the body is no longer able to effectively regulate blood sugar levels," explains Charna Dibner.
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The Tang Fuyi/Fu Wei research group collaborated to reveal the mechanism of tumorigenesis of small bowel cancer
Time of Update: 2022-10-02
Using the combination of strategies described above, the study had four main findings:First, identify the four cancer cell subtypes that are common in the tumor tissue of small bowel cancer: cell cycle enriched cancer cells, mitochondrial function-enriched cancer cells, metabolic cancer cells, and epithelial mesenchymal transformation characteristics enriched cancer cells, and a tumor tissue of small bowel cancer patients often contains these 4 subtypes of cancer cells at the same time.
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New research opens up the future of high-resolution genomics in microbial ecology
Time of Update: 2022-10-01
" ”essayLong-read-resolved, ecosystem-wide exploration of nucleotide and structural microdiversity of lake bacterioplankton genomes Image: A puzzle of microbial genome sequences Image source: Kyoto Global Newsletter/Yusuke OkazakiOne of the purposes of human beings wanting to better understand themselves is to understand the genetic makeup of microbes in their environment.
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Chinese scholars have developed a new dementia risk prediction model that can predict the onset of dementia ten years in advance
Time of Update: 2022-10-01
Image courtesy of the research team September 26 (Sun Guogen, Chen Jing) Chinese experts have carried out multidisciplinary cross-disciplinary joint research, using biomedical big data and artificial intelligence algorithms to develop a new dementia risk prediction model, and named it UKB-DRP.
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MIT develops new tool "Cell Rover": Tiny Wireless Real-Time Monitoring of Living Cells
Time of Update: 2022-10-01
" ” Researchers at MIT Media Lab have designed a miniature antenna that operates wirelessly inside living cells, opening up possibilities for medical diagnosis and treatment, as well as other scientific processes, because of the potential to monitor and even guide cellular activity in real time.