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Huge E.
Both type 1 and type 2 diabetes have been linked
Diabetes is a common disease that affects health
One effect of diabetes is damage to the innate immune system
An endogenous antibiotic
Scientists at Karolinska College have now investigated whether blood sugar levels in people with diabetes (type 1, type 2 or prediabetes) are related to psoriasis, an endogenous antibiotic that is part of
Using samples of the patient's urine, bladder cells and serum, the researchers analyzed levels of psoriasis and other peptides to ensure that the bladder mucosa remains intact and prevents infection
"We found that high concentrations of glucose lowered levels of the antimicrobial peptoid psoriasis, while insulin had no effect," Annelie Bruner said
Estrogen therapy reduces the number of bacteria
Professor Braune's team has previously demonstrated that treatment with estrogen can restore the protective function of human and mouse bladder cells, thereby helping to regulate the immune response to UTIs
"We now plan to study the underlying mechanisms of infection in diabetic patients in greater depth," said
Diabetes downregulates the antimicrobial peptide psoriasin and increases E.
