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Nature Sub-Journal: Using "invisible" chromosomes to transmit positive traits
Time of Update: 2022-10-01
essayMassive crossover suppression by CRISPR–Cas-mediated plant chromosome engineering Figure: Genetic exchange of paternal and maternal traits typically occurs over the entire length of a chromosome.
essayMassive crossover suppression by CRISPR–Cas-mediated plant chromosome engineering Figure: Genetic exchange of paternal and maternal traits typically occurs over the entire length of a chromosome.
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The discovery could boost platelet production to combat blood shortages
Time of Update: 2022-10-01
A new finding from the University of Virginia School of Medicine could allow doctors to increase coagulation platelet production as needed, in time to be discovered after the Red Cross declared a national blood "crisis" earlier this year.
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The carp virus taught researchers immunology
Time of Update: 2022-10-01
The team of Professor Alain Vanderplasschen, a virologist and immunologist at Liège University, published an article in the journal Nucleic Acid Study, reports that a decade of research on carp viruses has been using a protein domain called Zalpha (Zα) to inhibit the defense mechanisms of host cells.
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Why do Scitech whales not get brain damage while swimming?
Time of Update: 2022-10-01
”Retia mirabilia: Protecting the cetacean brain from locomotion-generated blood pressure pulses In today's news, 230 pilot whales stranded on the west coast of Australia's Tower Island, and some people speculate that it may be due to the impact of magnetic field pulses.
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Nature Medicine: Pressed the reset button for autoimmune diseases
Time of Update: 2022-10-01
"We have been able to help six young patients with life-threatening systemic lupus erythematosus and completely cure their disease with CAR-T cell therapy," said Professor Georg Schett, chair of the Department of Rheumatology and Immunology Medicine.
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A new way to identify the "safe haven" of gene therapy
Time of Update: 2022-10-01
essayGenomics and epigenetics guided identification of tissue-specific genomic safe harbors Photo: Co-first author Dewan Shrestha (left), corresponding author Dr. Yong Cheng (center) and co-author Ruiqiwu (right).
essayGenomics and epigenetics guided identification of tissue-specific genomic safe harbors Photo: Co-first author Dewan Shrestha (left), corresponding author Dr. Yong Cheng (center) and co-author Ruiqiwu (right).
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Two new papers: How gut bacteria "eat" high-fiber protection gut
Time of Update: 2022-10-01
David said that the previous participants who consumed the most fiber had minimal changes in their microbiome, and the type of supplement really didn't matter, possibly because they already had a more desirable population of gut bacteria.
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eLife: Cancer cells can form temporary structures that evade immunotherapy
Time of Update: 2022-10-01
”essayTransient cell-in-cell formation underlies tumor relapse and resistance to immunotherapy The findings, published in the journal eLife, provide a new theory of how tumor cells can avoid being destroyed by the immune system.
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This pile of yellow compounds has a potential basis for curing the coronavirus
Time of Update: 2022-10-01
”Salen: Insight into the Crystal Structure, Hirshfeld Surface Analysis, Optical Properties, DFT, and Molecular Docking Studies The researchers found that Saren was able to effectively bind some proteins of the coronavirus SARS-CoV-2.
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PNAS: Clues to the evolutionary origins of brown algae that could be used in health and biofuel research
Time of Update: 2022-10-01
Biologists at Colorado State University, in collaboration with researchers in Germany and China, have revealed fundamental insights into the evolution of these algae that produced a new brown pigment, known as fucoxanthin.
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iScience: Genetic defects cause tooth enamel malformations
Time of Update: 2022-10-01
To study in detail the role of Adam 10/Notch signaling in enamel formation and pathology, and to analyze changes in tooth cells and enamel structure after genetic mutations, the researchers used state-of-the-art genetic, molecular, and imaging tools.
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Uncover the secrets of the skin – the formation of skin is different throughout the body
Time of Update: 2022-10-01
JCI Insight, 2022; 7 (16) Why are some parts of the body more susceptible to skin diseases than others?Two new studies by UC Davis Health explore how differences in skin composition can lead to skin diseases such as psoriasis and atopic dermatitis.
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Nature's New Breakthrough: First Confirmation of the Origin of a Deadly Brain Tumor!
Time of Update: 2022-10-01
essayRhombic lip implicated in origins of high-risk medulloblastoma Image: From left to right: Dr. Paul Northcott, Dr. Kyle Smith, Dr. Brian Gudenas, and Dr. Laure Biannic.
essayRhombic lip implicated in origins of high-risk medulloblastoma Image: From left to right: Dr. Paul Northcott, Dr. Kyle Smith, Dr. Brian Gudenas, and Dr. Laure Biannic.
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Stanford's new finding: SARS-CoV-2 infects adipose tissue, creating an inflammatory storm cloud
Time of Update: 2022-10-01
But the new study offers a more immediate cause: The SARS-CoV-2 virus that causes COVID-19 can directly infect adipose tissue (which most of us just call "fat" in general).
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Novel atypical G protein signal transduction regulator homologous domain
Time of Update: 2022-10-01
Through structural biology, Liu Jinsong's research group at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, discovered a novel class of atypical G protein signal transduction regulators (RGS) homologous domains (RGS homology, RH) in sorted transporters (SNXs).
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"Alien" changes in the fungus lead to immune escape events
Time of Update: 2022-10-01
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways Microscopic imaging experiments developed by Olivier et al.
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The team of Han Zeguang and Su Xianbin of Shanghai Jiaotong University proposed a new strategy for predicting tumor clonal structure
Time of Update: 2022-10-01
Recently, Ann NY Acad Sci, a classic academic journal with nearly 200 years of publishing history, published a paper entitled "Accurate tumor clonal structures require single-cell analysis" by Han Zeg
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Subvert the new theory of "assembly of the basic structure of life"
Time of Update: 2022-10-01
As part of her postdoctoral training at the University of Massachusetts Amherst, Di Jia is the lead author of the study, saying: "Dipoles can make polyelectrolytes behave more like polydhedrons, exhibiting a 'reverse polymer electrolyte effect.
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Relieves the immune system's deadly lung response
Time of Update: 2022-10-01
essayPTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils Image: CSHL researchers have found that treating mice with a drug candidate that inhibits a protein called PTP1B prevents deadly lung inflammation in mice.
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Chai Jijie and collaborators in the School of Life Sciences first revealed the bifunctional disease resistance mechanism of plant immune receptor proteins
Time of Update: 2022-10-01
In a long battle against pathogenic bacteria, plants have evolved a fine, complex, multi-layered immune system to protect themselves from aggression. Pattern Recognition Receptors (PRRs) localized to
