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    Home > Biochemistry News > Biotechnology News > Two new papers: How gut bacteria "eat" high-fiber protection gut

    Two new papers: How gut bacteria "eat" high-fiber protection gut

    • Last Update: 2022-10-01
    • Source: Internet
    • Author: User
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    The human gut grows on fermentable fibers, not burgers
    .


    Dietary fiber has other benefits
    in addition to the advertised convenience of defecation.


    "We have evolved to rely on the microbiome for the nutrients we produce," said Zack Holmes, a former doctoral student in David's lab who is the co-author
    of two new papers on fiber.


    When your gut bacteria eat high-fiber foods, they produce more short-chain fatty acids, which can protect you from gut disease, colorectal cancer, and even obesity
    .


    David's team was interested in whether it was necessary to offer "personalized" fiber supplements to different people, given the wide variety of supplements
    on the market.


    "We didn't see a big difference between the fiber supplements we tested
    .


    David said: "No matter which supplement you choose, it seems that your microbiome will thank you
    with more butyrate.


    The average U.


    The Duke experiment tested three main fermentable fiber supplements: inulin, Benefiber, and galactosaccharides (GOS),
    named after Bimuno.


    David said that the previous participants who consumed the most fiber had minimal changes in their microbiome, and the type of supplement really didn't matter, possibly because they already had a more desirable population
    of gut bacteria.


    Conversely, participants who consumed the least amount of fiber had the greatest
    increase in butyrate regardless of which supplement they consumed.


    Using artificial intestinal starter cultures, the researchers found that gut microbes begin to consume fiber after the first dose and digest
    quickly at the second dose.


    These findings are encouraging
    .


    Reference: "Microbiota Responses to Different Prebiotics Are Conserved Within Individuals and Associated with Habitual Fiber Intake," Zachary Holmes, Max Villa, Heather Durand, Sharon Jiang, Eric Dallow, Brianna Petrone, Justin Silverman, Pao-Hwa Lin and Lawrence David, 29 July 2022, Microbiome.


    “Ecological Memory of Prior Nutrient Exposure in the Human Gut Microbiome,” Jeffrey Letourneau, Zachary Holmes, Eric Dallow, Heather Durand, Sharon Jiang, Verónica Carrion, Savita Gupta, Adam Mincey, Michael Muehlbauer, James Bain and Lawrence David, 23 July 2022, ISME Journal.



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