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iScience: Genetic defects cause tooth enamel malformations

 Last Update: 2022-10-01
 Source: Internet
 Author: User

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According to a study conducted by the UZH Dental Medical Center, mutations in a certain molecule can cause serious damage
to the enamel structure and mineral composition of mice tooth.

Enamel is the hardest organic tissue in nature
.

Focus on the study of Adam10 molecules

A team of researchers from the Dental Medical Center of the University of Zurich has now discovered for the first time a key gene network
that causes severe enamel defects.

Defects in enamel structure and mineral composition

Scientists were able to show a strong link
between impaired Adam 10/Notch function and tooth enamel defects.

New avenues of prevention and treatment

Mitsiadis said understanding the genetic code that governs tooth development, understanding the molecular connections in the process of enamel formation, and the effects of mutations that lead to enamel malformations opens up new horizons
in the field of prevention and treatment.

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