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Scientists use zebrafish to understand the link between the immune system and regeneration
Time of Update: 2022-10-01
A new study from the Stowers Institute for Medical Research used highly regenerated zebrafish to investigate the timing and genetic procedures of macrophages (a type of white blood cell) during the repair and regeneration of zebrafish sensory organs.
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Neglected "glycans" can regulate the spike protein function of COVID-19
Time of Update: 2022-10-01
Now, Neelamegham, along with other scientists, has elucidated the role glycans may play in the function of the SARS-CoV-2 virus that causes COVID-19.
Now, Neelamegham, along with other scientists, has elucidated the role glycans may play in the function of the SARS-CoV-2 virus that causes COVID-19.
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Nature Genetics: Insertion and deletion accumulate over the regulatory regions of neurons, year by year
Time of Update: 2022-10-01
1038/s41588-022-01180-2 Research teams led by institutions such as Harvard Medical School and Boston Children's Hospital recently adopted a new single-cell DNA sequencing method and found that human neurons accumulate relatively low-frequency indels year by year, which seems to be particularly common in regulatory elements.
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The researchers tested a new hypothesis that explains the autoimmunity of people with type 1 diabetes
Time of Update: 2022-10-01
essayHypothesis: Induction of Autoimmunity in Type 1 Diabetes—A Lipid Focus Type 1 diabetes mellitus (T1D) is an autoimmune disease in which the pancreas secretes little or no insulin.
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New research shows that breakthrough infections can greatly enhance immunity to COVID-19
Time of Update: 2022-10-01
001 According to a recent study from the University of Health and Science of Oregon (OHSH), both vaccine-booster shots and breakthrough infections after vaccination can greatly enhance the immune response and help protect people against the new coronavirus (SARS-CoV-2) variant.
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New research reveals how E. coli cells evade antimicrobial treatment
Time of Update: 2022-10-01
Professor Jin Lijian of the University of Hong Kong said: "This important new discovery means that persistent cells remain active even in dormant conditions, which may be one of the key ways they can survive high-dose antimicrobial therapy.
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New study finds that the virus may have "eyes and ears" for us.
Time of Update: 2022-10-01
Figure: A delta bacteriophage that was first discovered in a new study in Frontiers in Microbiology with a binding site of CtrA, a protein produced by the host of a bacteriophage that regulates the production of bacterial and flagella.
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Chai Jijie and collaborators in the School of Life Sciences first revealed the bifunctional disease resistance mechanism of plant immune receptor proteins
Time of Update: 2022-10-01
In a long battle against pathogenic bacteria, plants have evolved a fine, complex, multi-layered immune system to protect themselves from aggression. Pattern Recognition Receptors (PRRs) localized to
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Chinese scholars have made progress in the study of active intermediates
Time of Update: 2022-10-01
Figure Structure, properties and catalytic study of amino anionic metal hydrogen active intermediates With the support of the National Natural Science Foundation of China (approval number: 22171159, 21822106), Liu Qiang's research group of Tsinghua University and the Lanyu research group of Zhengzhou University cooperated to make progress in the separation characterization and synthesis of catalytic hydrogenation reactive intermediates 。 The research results were published on September 12, 2022 in the journal "Structure, reactivity and catalytic properties of manganese-hydride amidate complexes".
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Nature's New Breakthrough: First Confirmation of the Origin of a Deadly Brain Tumor!
Time of Update: 2022-10-01
essayRhombic lip implicated in origins of high-risk medulloblastoma Image: From left to right: Dr. Paul Northcott, Dr. Kyle Smith, Dr. Brian Gudenas, and Dr. Laure Biannic.
essayRhombic lip implicated in origins of high-risk medulloblastoma Image: From left to right: Dr. Paul Northcott, Dr. Kyle Smith, Dr. Brian Gudenas, and Dr. Laure Biannic.
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Why do Scitech whales not get brain damage while swimming?
Time of Update: 2022-10-01
”Retia mirabilia: Protecting the cetacean brain from locomotion-generated blood pressure pulses In today's news, 230 pilot whales stranded on the west coast of Australia's Tower Island, and some people speculate that it may be due to the impact of magnetic field pulses.
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"Alien" changes in the fungus lead to immune escape events
Time of Update: 2022-10-01
The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways Microscopic imaging experiments developed by Olivier et al.
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The team of Han Zeguang and Su Xianbin of Shanghai Jiaotong University proposed a new strategy for predicting tumor clonal structure
Time of Update: 2022-10-01
Recently, Ann NY Acad Sci, a classic academic journal with nearly 200 years of publishing history, published a paper entitled "Accurate tumor clonal structures require single-cell analysis" by Han Zeg
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iScience: Genetic defects cause tooth enamel malformations
Time of Update: 2022-10-01
To study in detail the role of Adam 10/Notch signaling in enamel formation and pathology, and to analyze changes in tooth cells and enamel structure after genetic mutations, the researchers used state-of-the-art genetic, molecular, and imaging tools.
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Nature Medicine: Pressed the reset button for autoimmune diseases
Time of Update: 2022-10-01
"We have been able to help six young patients with life-threatening systemic lupus erythematosus and completely cure their disease with CAR-T cell therapy," said Professor Georg Schett, chair of the Department of Rheumatology and Immunology Medicine.
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Relieves the immune system's deadly lung response
Time of Update: 2022-10-01
essayPTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils Image: CSHL researchers have found that treating mice with a drug candidate that inhibits a protein called PTP1B prevents deadly lung inflammation in mice.
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Stanford's new finding: SARS-CoV-2 infects adipose tissue, creating an inflammatory storm cloud
Time of Update: 2022-10-01
But the new study offers a more immediate cause: The SARS-CoV-2 virus that causes COVID-19 can directly infect adipose tissue (which most of us just call "fat" in general).
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Uncover the secrets of the skin – the formation of skin is different throughout the body
Time of Update: 2022-10-01
JCI Insight, 2022; 7 (16) Why are some parts of the body more susceptible to skin diseases than others?Two new studies by UC Davis Health explore how differences in skin composition can lead to skin diseases such as psoriasis and atopic dermatitis.
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Novel atypical G protein signal transduction regulator homologous domain
Time of Update: 2022-10-01
Through structural biology, Liu Jinsong's research group at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, discovered a novel class of atypical G protein signal transduction regulators (RGS) homologous domains (RGS homology, RH) in sorted transporters (SNXs).
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Two new papers: How gut bacteria "eat" high-fiber protection gut
Time of Update: 2022-10-01
David said that the previous participants who consumed the most fiber had minimal changes in their microbiome, and the type of supplement really didn't matter, possibly because they already had a more desirable population of gut bacteria.
