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According to a recent study from the University of Health and Science of Oregon (OHSH), both vaccine-booster shots and breakthrough infections after vaccination can greatly enhance the immune response and help protect people against the new coronavirus (SARS-CoV-2) variant
.
The article, titled "Omicron neutralizing antibody response following booster vaccination compared with breakthrough infection," was recently published in the journal Med
.
The researchers concluded: "As the number of cases infected with the Omikron variant increases, and global vaccination and enhanced vaccination campaigns continue, more and more people around the world will gain access to a robust immune response that may be effective against future SARS-CoV-2 variants
.
In the study, the researchers took blood samples from 99 OHSU employees and measured their immune responses
.
In both groups three months after the third dose of the vaccine booster and one month after the breakthrough infection, they both detected an equally strong immune response – a significant increase
in intensity, potency and breadth.
Marcel Curlin, an associate professor at the Oregon University of Health and Science School of Medicine, said: "In the early days of the pandemic, the mortality rate was very high for certain vulnerable groups, such as the elderly in nursing homes, but this is slowly changing
.
Co-corresponding author Dr.
"We expect that an upgraded vaccination strategy specific to the variant will significantly increase the breadth of the immune response and help people better defend against the SARS-CoV-2 variant," he said
.
Compared to the early days of the pandemic, the SARS-CoV-2 virus is no longer new
to the human immune system.
Dr Curlin said the new study is likely to reflect the fact that viruses are evolving to spread more easily, but less harmfully
.
"Evolutionary pressures are driving viruses to find more ways to infect humans at the cost of reduced pathogenicity," he said
.
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Marcel E.
