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PNAS: tumor-testicular genes can cause persistent chromosomal instability
Time of Update: 2022-10-19
With the support of the National Key Research and Development Program and Guangdong Province Leading Talents, Alexander Strunnikov's team at the Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, found that the Cancer-Testis (CT) gene can cause persistent chromosomal instability.
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Exploring the evolution of human disease from a metabolic rather than a genetic perspective
Time of Update: 2022-10-19
Molecular Genetics and Metabolism, 2022; 137 (3): 292 A new Yale-led study has found that we can detect not only our ancestors in genes, but also in our metabolism.
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Chinese scholars have made new progress in the pathogenesis and treatment strategies of chronic sinusitis
Time of Update: 2022-10-19
Based on the results of single-cell sequencing analysis, the research team deeply explored the pathogenic mechanism and therapeutic new targets of diseases through a series of cytology, molecular biology and animal experiments.
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Water risks and crises in Central Asia are intensifying
Time of Update: 2022-10-19
Based on the water stress index (WSI), safe drinking water services and water pollution indicators, the research team of Chen Yaning, a researcher team of Chen Yaning, State Key Laboratory of Desert and Oasis Ecology, Chinese Academy of Sciences, conducted a multi-angle assessment of water resource utilization and water crisis process in five Central Asian countries, and quantitatively analyzed the impact of climate change, population growth, poverty, urbanization and transboundary river management on water crisis.
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Does PNAS stress really protect your body?
Time of Update: 2022-10-19
”Reference: Chronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling New research suggests it's possible.
”Reference: Chronic stress induces colonic tertiary lymphoid organ formation and protection against secondary injury through IL-23/IL-22 signaling New research suggests it's possible.
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The team of Xu Shuhua/Zhang Guoqing/Fan Shaohua released the PGG.SV of the human genome structural variation database and computational analysis platform
Time of Update: 2022-10-19
On October 16, 2022, the internationally renowned academic journal Nucleic Acids Research The human genome structural variation PGG. SV database developed by Professor Xu Shuhua's team from the Schoo
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Yawen Zhang's research group in the School of Chemistry has made new progress in the regulation of the interfacial electronic structure and catalytic performance of nano-cerium oxide systems
Time of Update: 2022-10-19
Recently, Professor Yawen Zhang's research group from the CeO2-based supported catalytic materials developed two methods for precise control of the electronic structure of the interface, the electrochemically induced interface control strategy and the ammonia heat treatment interface control strategy, respectively, to enhance the interface electronic interaction and weaken the interface electronic interaction (Figure 1).
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Plasma prostaglandins are associated with the incidence of diabetes
Time of Update: 2022-10-19
After adjusting for potential confounding factors including age, sex and waist circumference, smoking and drinking habits, LDL cholesterol, systolic blood pressure and antihypertensive drugs, elevated prostaglandin levels were found to be positively correlated with the presence of diabetes, with the highest quartile of prostaglandin levels almost twice as likely to develop diabetes as the lowest.
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Cell: Pain has an unexpected protective effect
Time of Update: 2022-10-19
Original text searchNociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production and gut barrier protection Pain has long been considered one of the most reliable tools in evolution to detect the presence of injury and signal something is wrong with our body — an alert system that reminds us to stop and pay attention to our bodies.
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Due to oscillations in the immune response, viral infections are less common in people with Down syndrome, but more severe
Time of Update: 2022-10-19
The new findings, published Oct. 14 in the journal Immunology, suggest that this is caused by increased expression of an antiviral cytokine type I interferon (IFN-I), which is encoded in part by chromosome 21.
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Science Journal: Testosterone is an ally of macrophages in the fight against adrenal cancer
Time of Update: 2022-10-19
essaySexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development Figure: Macrophages attack adrenal tumors in male mice.
essaySexually dimorphic activation of innate antitumour immunity prevents adrenocortical carcinoma development Figure: Macrophages attack adrenal tumors in male mice.
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The neural basis of Neuron's "Yerkes-Dodson law"
Time of Update: 2022-10-19
"We wanted to look at how the sensory information transmitted by neurons in the cortex is altered by the degree of motivation, and to what extent motivation affects performance in learning and decision-making tasks," explains Sami El-Boustani, lead author of the study.
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The nuclear receptor RORβ is expected to be a new target for the prevention and treatment of osteoarthritis
Time of Update: 2022-10-19
The research team found that activating a specific protein in these cells called RORβ can restore multiple factors needed for healthy joints, helping to control inflammation.
The research team found that activating a specific protein in these cells called RORβ can restore multiple factors needed for healthy joints, helping to control inflammation.
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Natural metabolites convert "bad" fats into "good" fats
Time of Update: 2022-10-19
Metabolites are substances that are produced and used during these metabolic processes — or, as a new finding by Scripps Research and its drug development arm, Calibr, they may also be effective molecules for treating serious diseases.
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NEJM: Never-before-reported mitochondrial disease found in identical twins
Time of Update: 2022-10-19
Markhard, Irene Yee, Sheila Clever, Alan Cahill, Hardik Shah, Zenon Grabarek, Tsz-Leung To, Vamsi K.
Markhard, Irene Yee, Sheila Clever, Alan Cahill, Hardik Shah, Zenon Grabarek, Tsz-Leung To, Vamsi K.
Markhard, Irene Yee, Sheila Clever, Alan Cahill, Hardik Shah, Zenon Grabarek, Tsz-Leung To, Vamsi K.
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Here it comes! The first full-length transcriptome of the shuttle and the white shuttle responding to drought stress!
Time of Update: 2022-10-14
Recently, the team of Professor Lu Guanghui of the Institute of Arid Ecological Environment of Xinjiang University published a report entitled "Characterization of the gene expression profile response to drought stress in Haloxylon using PacBio single-molecule real-time" in Frontiers in Plant Science and Illumina sequencing", which obtained the first full-length transcriptome of PacBio full-length transcription (Iso-seq) in response to drought stress, laying a foundation for further study of its regulatory mechanisms.
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Fish fossils unearthed in China have injected new life into the evolutionary hypothesis of fins and limbs
Time of Update: 2022-10-14
"Galeaspid anatomy and the origin of vertebrate paired appendages A lifelike reconstruction of the life of Tujiaaspis vividus A batch of fossils unearthed in Chinese rocks dating back about 436 million years ago first revealed the mysterious armored fish, a member of an extinct jawless fish with pairs of fins.
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Inspired by plants: Develop new processes for the growth of synthetic materials that can grow like plants
Time of Update: 2022-10-14
The researchers used this material growth pattern to produce a soft robot that could grow quickly and continuously, thus solving the main limitations of the growth process of soft robots due to limited scalability, lack of permanent structure, and inability to pass through tortuous paths, demonstrating the potential of soft robot growth to provide new capabilities in the field of manufacturing and soft robots.
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Neuron New Technology Unlocks Hard-to-Study 'Sense of Smell'
Time of Update: 2022-10-14
Long-range functional loops in the mouse olfactory system and their roles in computing odor identity Figure: The left column image shows the monk cap cells (top) and clustered cells (bottom) of the mouse olfactory bulb.
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Studies have shown for the first time that ticks weaken the immune response of the skin
Time of Update: 2022-10-14
A team of researchers led by Johanna strorol and Georg Stary of the Department of Dermatology at the Medical University of Vienna showed that tick saliva inhibits the skin's defense function, thereby increasing the risk of tick-borne encephalitis (TBE) or Lyme disease and other diseases.
