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Cell: A new family of mobile genetic elements that allow the horizontal transfer of large genes
Time of Update: 2023-02-02
From the tropics to the poles, from the surface to a few hundred feet below, the world's oceans are filled with one of the smallest organisms: bacteria called Prochlorococcus, which, despite their small size, are collectively responsible for a significant portion of the ocean's oxygen production.
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Harvard University: Treating cancer with cancer
Time of Update: 2023-02-02
Researchers from Khalid Shah's lab, Harvard-affiliated BWH, have developed a new cellular therapy approach that eliminates established tumors and induces long-term immunity, training the immune system so that it can prevent cancer recurrence.
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PNAS: a novel mechanism for potassium channel regulation
Time of Update: 2023-02-02
On January 6, 2023, the journal PNAS published a research paper entitled "DNA topoisomerase 2-associated proteins PATL1 and PATL2 regulate the biogenesis of hERG K+ channels" online, which was comple
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A new way to monitor blood flow to the brain
Time of Update: 2023-02-02
Continuous, non-invasive blood flow monitoring can help treat serious brain disorders.
Continuous, non-invasive blood flow monitoring can help treat serious brain disorders.
Continuous, non-invasive blood flow monitoring can help treat serious brain disorders.
Continuous, non-invasive blood flow monitoring can help treat serious brain disorders.
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A more accurate and effective test than current Lyme disease tests
Time of Update: 2023-02-02
Testing Raman spectroscopy as a diagnostic approach for Lyme disease patients Two scientists at Texas A&M University are studying how to improve the treatment of Lyme disease, and they have developed a more accurate and effective detection method than current infection detection.
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Nature stops aging – strengthens immune cells and improves brain waste removal
Time of Update: 2023-02-02
In this study, we treated aged mice with a molecule that activates senescent immune cells, which plays a role in improving brain fluid flow and waste removal.
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Cell: Young microbes and old microbes work together to extend their lifespan
Time of Update: 2023-02-02
”Crick's first author and researcher Clara Correia-Melo, who soon began her own lab at the Leibniz Institute on Aging in Jena, Germany, the Fritz Lipmann Institute (FLI), said: "The study of cellular metabolism has historically focused on what happens inside cells, where hundreds of chemical reactions take place, produce many metabolites and affect the environment inside cells.
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PNAS: A cellular mechanism for improving physical fitness through exercise training
Time of Update: 2023-02-02
The researchers recorded wild-type Caenorhabditis elegans swimming or crawling, observing typical age-related declines in the animals' physical health within 15 days of reaching adulthood.
The researchers recorded wild-type Caenorhabditis elegans swimming or crawling, observing typical age-related declines in the animals' physical health within 15 days of reaching adulthood.
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Cell Discov Shanghai Drug Institute collaborates to uncover the molecular mechanism by which adenosine receptor A2BR binds endogenous and selective ligands
Time of Update: 2023-02-02
Adenosine (ADO) is widely distributed in various tissues and organs of the human body, and regulates a variety of important physiological and pathological processes in the human body by acting on ade
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Nature Medicine: Novel T-cell receptor therapies show early anti-tumor activity
Time of Update: 2023-02-02
David Hong, MDSource: University of Texas Anderson Cancer CenterAfamitresgene autoleucel (formerly ADP-A2M4, abbreviated afami-cel) is an adoptive T cell receptor (TCR) therapy targeting the MAGE-A4 cancer antigen that has achieved significant clinical efficacy in patients with multiple solid tumor types in a Phase I clinical trial led by researchers at the University of Texas MD Anderson Cancer Center.
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The first to mine the fungal genome using multiple base editing
Time of Update: 2023-02-02
Xue Sherry Gao, a chemical and biomolecular engineer at Rice University, and his collaborators used a method to simultaneously modify multiple sites in the fungal genome, tricking the fungi into revealing their best-kept secrets, speeding up the pace of new drug discovery.
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Ding Jingheng's research group and Shao Feng's team at Beisheng Institute revealed that bacterial effector proteins antagonize host cell pyrosis ...
Time of Update: 2023-02-02
As an important natural immune response of the body, cell pyrosis plays a key role in antagonizing and eliminating pathogenic infections. When gram-negative bacteria invade host cells, the important
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300 liver cancer long-term survival hearts warm winter! Experts remind: early prevention and early treatment are the key
Time of Update: 2023-02-02
In just a few days, the South + client "394 Liver Cancer Long-term Survival Voices" public welfare collection activity supported by Merck Sharp & Dohme China received 300 good wishes from everyone, m
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The mRNA monkeypox vaccine is doing well, but it may not be on the market
Time of Update: 2023-02-02
In May last year, when Moderna announced the development of an mRNA monkeypox vaccine, the monkeypox epidemic in the United States was just beginning, with an average of two new cases reported per day.
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A protein called Menin causes abnormal inactivation of specific genes in cancer cells
Time of Update: 2023-02-01
"Article: Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes Image: Associate Professor Marian Burr.
"Article: Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes Image: Associate Professor Marian Burr.
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Molecular basis of plant-based SUVH6 enzyme catalytic site-specific H3K9 methylation
Time of Update: 2023-02-01
A working model of the SUVH6-ASI1 module regulating H3K9me2 deposition and gene expression The international academic journal PNAS published a research paper entitled "Molecular Basis of Locus-specific H3K9 Methylation Catalyzed by SUVH6 in Plants" in collaboration between Duan Chengguo Research Group of the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences and Du Jiamu Research Group of Southern University of Science and Technology.
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No need to worry about which embryo to transfer for IVF, it can be scored by artificial intelligence!
Time of Update: 2023-02-01
Fig. 2 The blastocyst cavity gradually expands and hatches from the zona pellucida (Source: [1])However, regardless of the day of the embryo, the above evaluation system has traditionally only observed the embryo at a specific time point, and the dynamic information during embryonic development is lost.
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Cell Discovery: "Lock Up" Omicron! Chinese scientists have developed bispecific antibodies that can target all new crown variants to prevent and treat both
Time of Update: 2023-02-01
1038/s41421-022-00509-9 Recently, Chinese scientists published a paper in the journal Cell Discovery [1], proposing a new bispecific antibody that can effectively bind to 16 new coronavirus variants tested, including the widely circulating BA.
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Nature Aging has discovered a new sign of aging: ceramides accumulate in aging muscle
Time of Update: 2023-02-01
Original:Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia Finally, the researchers wanted to investigate whether inhibiting ceramide synthesis could also prevent muscle loss in humans.
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Small biosynthetic melanin nanoparticles for photoacoustic imaging-guided photothermal therapy
Time of Update: 2023-02-01
The experimental results show that the biosynthesized melanin nanoparticles have good photothermal stability, high photothermal conversion efficiency, good biocompatibility, excellent photoacoustic imaging performance, and can be used as an environmentally friendly photothermal therapy agent for photoacoustic imaging-guided photothermal therapy Important research value and application prospects.
