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Science answers a century-old mystery in botany
Time of Update: 2023-01-06
Hydraulic failure as a primary driver of xylem network evolution in early vascular plants Illustration: Animated schematic of the spread of embolism between two stem cross-sectional ducts.
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Science answers a century-old mystery in botany
Time of Update: 2023-01-06
Hydraulic failure as a primary driver of xylem network evolution in early vascular plants Illustration: Animated schematic of the spread of embolism between two stem cross-sectional ducts.
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Deliver CRISPR editing tools with bacteriophages to precisely edit specific bacteria of the soil microbiota
Time of Update: 2023-01-06
Scientists at North Carolina State University have developed a way to precisely edit individual genes of a target bacterial species in a microbial community using bacteriophages that attack bacteria.
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Cell Rep: Blocks DNA production by targeting the enzyme POLtheta in cancer therapy
Time of Update: 2023-01-06
”POLΘ fills the gap in single-stranded DNAFirst authors Anna Schlempf and Sarah Bernardo focused on the enzyme POLΘ (DNA polymerase), which is part of the cell's DNA repair mechanism and whose loss is synthetically fatal with BRCA1 mutations.
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THE LEMIN LAB PUBLISHES PAPERS IN MICROBIOLOGY SPECTRUM
Time of Update: 2023-01-06
02479-22Published online: OCT 2022Document type: Article; Early AccessAttachment: Full text link ：Comprehensive Assessment of Subtyping Methods for Improved Surveillance of Foodborne Salmonella（IF=8.
02479-22Published online: OCT 2022Document type: Article; Early AccessAttachment: Full text link ：Comprehensive Assessment of Subtyping Methods for Improved Surveillance of Foodborne Salmonella（IF=8.
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The collaborative research of Yu Yongfu's research group of Fudan University has made progress in the field of diabetes
Time of Update: 2023-01-06
This study demonstrates that children with diabetes have an increased risk of early onset kidney disease overall and specific types, and that preventing and treating diabetes early in childhood may significantly reduce the risk of developing kidney disease later in life.
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Resolving the genetic drivers of head and neck cancer
Time of Update: 2023-01-06
"We found that not only the 9p21 locus on chromosome 9p is involved, but also the 9p24 locus, which may be more important in driving resistance in immune checkpoint therapies; Surprisingly, we found that an increase in these gene regions, at least in the case of HPV-negative head and neck squamous cell carcinoma, was associated with ICT survival benefits.
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Nine paralyzed patients regained the ability to walk, and scientists discovered the neurons responsible for walking
Time of Update: 2023-01-06
In a study published Nov. 9 in the journal Nature, researchers followed nine paralyzed patients who received an electrical stimulation regimen who regained the ability to walk and compared their findings to mice that received similar treatments.
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Nine paralyzed patients regained the ability to walk, and scientists discovered the neurons responsible for walking
Time of Update: 2023-01-06
In a study published Nov. 9 in the journal Nature, researchers followed nine paralyzed patients who received an electrical stimulation regimen who regained the ability to walk and compared their findings to mice that received similar treatments.
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There is evidence that SARS-CoV-2 alters the RNA of infected cells
Time of Update: 2023-01-06
Scientists at the Federal University of São Paulo (UNIFESP) in Brazil have demonstrated for the first time that infection with the SARS-CoV-2 virus that causes COVID-19 alters the function of host cell RNA.
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Nature Cancer has unveiled a new CRISPR-based technology that can cut the cancer genome and study changes in copy number
Time of Update: 2023-01-06
3 deletions as mediators of immune evasion and metastasis Research focusMACHETE is a new CRISPR-based technique that can efficiently study large-scale gene deletions in laboratory models.
3 deletions as mediators of immune evasion and metastasis Research focusMACHETE is a new CRISPR-based technique that can efficiently study large-scale gene deletions in laboratory models.
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Jing Wang's research team in the School of Pharmacy developed a single-base quantitative sequencing detection method for m6A
Time of Update: 2023-01-06
The m6 A detection technology "GLORI" (Glyoxal and nitrite-mediated deamination of unmethylated adenosine) developed by Wang Jing's research group breaks through the limitations of the above technology and achieves for the first time the real meaning of highefficiency, high sensitivity, high specificity, and no preference single base m6 A site detection, andm6 The modification level of the A site is absolutely quantified.
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Severe stressful events can exacerbate symptoms of prolonged COVID (COVID sequelae)
Time of Update: 2023-01-06
The study, led by researchers at New York University's Grossman School of Medicine, found that adult patients with this "primary life stressor" — which was present in more than 50 percent of follow-up patients — were at least twice as likely as other patients to struggle with depression, brain fog, fatigue, sleep problems and other long-term COVID-19 symptoms, the authors said.
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Cell A nutrient commonly found in the human diet contributes to the survival of a cancer-causing bacterium
Time of Update: 2023-01-06
A microbial transporter of the dietary antioxidant ergothioneine A new study from Yale University has found that a nutrient commonly found in the human diet contributes to the survival of a cancer-causing bacterium.
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Researchers have discovered a new oral drug that lowers cholesterol
Time of Update: 2023-01-06
In the new study, Stamler and his colleagues show that nitric oxide can also target and inhibit PCSK9, thereby lowering cholesterol.
In the new study, Stamler and his colleagues show that nitric oxide can also target and inhibit PCSK9, thereby lowering cholesterol.
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Cell publishes the functional pattern of basic genes! The function of more than 5,000 genes needed for human cells to survive
Time of Update: 2023-01-06
Using a novel, ensemble, image-based screening method, a team of scientists at the Whitehead Institute, the Massachusetts Institute of Technology and Harvard University's Broad Institute systematically assessed the function of more than 5,000 basic human genes.
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Science Advances: Exome sequencing studies discover potential therapeutic targets for diabetes
Time of Update: 2023-01-06
add5430 Through a large-scale exome sequencing association study, researchers began to use MAP3K15 as a potential target for diabetes treatment.
add5430 Through a large-scale exome sequencing association study, researchers began to use MAP3K15 as a potential target for diabetes treatment.
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Wang Likun's team discovered a new mechanism by which tumor cell unfolded proteins respond to regulate tumor immunity
Time of Update: 2023-01-06
" 。 The study found that the activation of IRE1α/XBP1 signaling pathway in tumor cells inhibits anti-tumor immunity and promotes tumor growth by promoting the synthesis and secretion of own cholesterol.
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Cell: Cao Peng et al. revealed the "nausea-vomiting" brain-gut transmission neural pathway
Time of Update: 2023-01-06
For the first time, Cao Peng, a researcher at the Beijing Institute of Life Sciences, and collaborators have mapped detailed neural pathways in mice from the gut to the brain, which could help scientists develop better anti-vomiting drugs for cancer patients undergoing chemotherapy.
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eLife: Gene interactions can classify intestinal tumors
Time of Update: 2023-01-06
"Gene interaction perturbation network deciphers a high-resolution taxonomy in colorectal cancer This new classification of bowel cancer will help people understand the disease and may eventually be used by doctors in precision medicine – helping them tailor the best treatment for individual patients.
