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Cell Research: A new generation of high-efficiency, low-toxicity tumor-restricted IL-15 prodrugs

 Last Update: 2021-08-28
 Source: Internet
 Author: User

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On August 10, 2021, " Cell Research " magazine published online a collaborative research paper "Tumor-conditional IL-15 pro-cytokine reactivates" by researcher Peng Hua from the Institute of Biophysics of the Chinese Academy of Sciences and Professor Fu Yangxin from the University of Texas Southwestern Medical Center.

At present, most tumor immunotherapies mainly focus on blocking immunosuppressive signals or activating immunostimulatory signals

Pro-IL-15 reduces systemic toxicity by blocking the activation and expansion of peripheral NK cells and T cells, but still retains effective anti-tumor ability

Dr.

Article link: https://

(Contribution: Peng Hua Research Group)

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