-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Scientists at the University of California, Irvine have discovered a new pharmacological approach that can reduce mitochondrial dysfunction that leads to diet-induced obesity
A high-fat diet can lead to obesity and metabolic disorders such as diabetes and fatty liver
Mitochondria play a vital role in the energy production of cells, and they also coordinate the cell's stress response
Exquisite genetic studies in mice have shown that keeping the mitochondrial network in a fusion state can overcome obesity caused by a high-fat diet
In their new research, Professor Edinger and her team used their patented water-soluble, oral bioavailability, synthetic sphingolipid SH-BC-893 to inhibit the endolysosomal transport protein required for mitochondrial fission
"The imbalance of leptin and adiponectin hormones that accompanies obesity has brought a difficult battle for people who want to lose weight
The results of this study indicate that SH-BC-893 may be a promising treatment for diet-induced obesity
Professor Edinger said: "This compound works through a new mode of action-if it is safe and effective for humans, it will provide a new weight loss strategy and can also be combined with other treatments
DOI 10.
