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Integrative molecules reveal the specificity of Claudin 6 therapeutic antibodies for solid tumors
Time of Update: 2023-02-03
”9A1。 Integral Molecular, an industry leader in membrane protein antibody discovery, has released a targeting mechanism for its Claudin 6 (CLDN6) antibody ctm-76, which is being developed in collaboration with Context Therapeutics for cancer therapy.
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Nature Medicine: A number of different pathways are associated with the sequelae of the new crown
Time of Update: 2023-02-03
Researchers at the Icahn School of Medicine at Mount Sinai have published a study linking changes in blood gene expression during COVID-19 to the acute sequelae of SARS-CoV-2 infection.
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West China Hospital 70,000 people study, allergic constitution, not easy to be infected with the new crown
Time of Update: 2023-02-03
In the study, the researchers analyzed 70,557 participants in the UK Biobank database who completed COVID testing between March 16 and December 31, 2020, and divided the participants into 4 groups: allergic rhinitis group (3201), asthma group (8624), rhinitis and asthma group (1407), control group (57325), and the study analyzed the impact of allergic rhinitis or asthma on the risk, severity and mortality of new crown infection。
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Science Advances: Proteins that may protect the heart in certain cancer treatment options
Time of Update: 2023-02-03
In two studies conducted on women undergoing breast cancer treatment, levels of a protein called hemagglutinin circulating in the blood were associated with increased cardiotoxicity.
In two studies conducted on women undergoing breast cancer treatment, levels of a protein called hemagglutinin circulating in the blood were associated with increased cardiotoxicity.
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The Lancet: The University of Hong Kong compares Sinovac head-to-head with mRNA vaccines to prevent Omicron
Time of Update: 2023-02-03
In addition, the third dose of vaccination activated spike protein-specific memory B cells and Omicron cross-reactive T cell responses, helping to reduce the severity of breakthrough infections and diseases, regardless of vaccine type.
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Stanford develops the latest vaccine: 100 times more powerful than mRNA, covering all strains
Time of Update: 2023-02-03
Recently, scientists from Stanford developed a ferritin-based new crown nanoparticle vaccine that can produce powerful, long-lasting, broad-spectrum neutralizing antibodies in non-human primates.
Recently, scientists from Stanford developed a ferritin-based new crown nanoparticle vaccine that can produce powerful, long-lasting, broad-spectrum neutralizing antibodies in non-human primates.
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Cell: For the first time, it has been discovered that there may be horizontal gene transfer between the gut microbiomes of the mother and baby
Time of Update: 2023-02-03
The perinatal period is a critical window for cognitive and immune system development, facilitated by the maternal and infant gut microbiomes and their metabolites. Recently, a study entitled "Mobile
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Chinese scholars and overseas collaborators have made progress in the controllable preparation of perovskite quantum dot solid films
Time of Update: 2023-02-03
Figure: Perovskite quantum dot solid film strategy and constructed high-performance semiconductor device With the support of the National Natural Science Foundation of China (approval numbers: 91956130, 62104116, 22121005), the scientific research team led by researcher Yuan Mingjian and Professor Chen Jun of Nankai University and the team of Professor Edward H.
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Li Chuanyun's team proposed the "stowaway hypothesis" that new genes unique to humans originated from lncRNA, revealing the molecular basis of "why people are human"
Time of Update: 2023-02-03
What makes us uniquely human? In recent years, whether the origin of a new gene might serve as the genetic basis for a trait unique to humans that encodes higher human intelligence has become one of
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Song's compatible team developed a manganese-based LNP-mRNA vaccine to enhance mRNA expression and improve immunogenicity, better preventing new crown mutant strains
Time of Update: 2023-02-03
Several vaccines have been approved to prevent COVID-19, including two mRNA vaccines, Comirnty (BNT162b2) developed by Pfizer/BioNTech, and Spikevax (mRNA-1273) developed by Moderna. With its unique
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Nature magazine selected 10 scientific figures: 31-year-old Chinese scientists were selected
Time of Update: 2023-02-03
”Original search: New crown predictor: Cao Yunlong, associate researcher of Peking University Biomedical Frontier Innovation Center and leading scientist of Beijing Changping LaboratoryCao Yunlong originally devoted himself to the research of single-cell genomics, but at the end of 2019, when he returned to China after graduating from Harvard University with a doctorate, he turned to virus research because of the arrival of the new crown epidemic.
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PNAS: The study reveals the molecular basis of H3K9 methylation specific to the catalytic site of plant SUVH6 enzymes
Time of Update: 2023-02-03
This pathway interacts with the DNA methylation-mediated SUVH histone methyltransferase recruitment mechanism to enhance the deposition of H3K9me2 at specific chromatin sites.
This pathway interacts with the DNA methylation-mediated SUVH histone methyltransferase recruitment mechanism to enhance the deposition of H3K9me2 at specific chromatin sites.
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PNAS: The new coronavirus affects brain function by infecting astrocytes in the human brain
Time of Update: 2023-02-03
The results showed changes in various biochemical pathways in the brain astrocytes of patients infected with the new coronavirus, especially those related to energy metabolism, compared to uninfected people.
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New advances in organoids! Human-mouse hybrid brain organoids respond to visual stimuli for the first time!
Time of Update: 2023-02-03
The research team combined transparent microelectrode arrays and two-photon imaging to perform longitudinal multimodal monitoring of human brain organoids transplanted into the retrosplenial cortex of adult mice 。 On December 26, 2022, the results were published in the journal Nature communications as "Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex".
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Nature sub-issue: Self-assembled proteins that store cell "memory" and can be "viewed" using light microscopy
Time of Update: 2023-02-03
Edward Boyden, a researcher at the Howard Medical Institute and a member of MIT's McGovern Brain Institute and Koch Integrative Cancer Institute, said: "At the organ or body scale, there are many changes that occur over the course of hours to weeks and these changes cannot be tracked over time.
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"Nature Cancer": Radiotherapy + immunity, better effect! Scientists have also discovered new prognostic markers
Time of Update: 2023-02-03
Pitroda from the Division of Radiation and Cell Oncology at the University of Chicago designed and conducted a investigator-initiated Phase 1/2, randomized clinical trial (COSINR study) evaluating the safety and efficacy of concurrent or sequential radiotherapy in combination with ICB (ipilimumab and nivolumab) as first-line treatment for metastatic non-small cell lung cancer (NSCLC).
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Professor Yi Lilin's team of Shanghai Jiaotong University released an open source simulation platform for intelligent optical transmission
Time of Update: 2023-02-03
On January 6th, the Optical Communication Simulation Software Development Seminar and Intelligent Optical Transmission Open Source Simulation Platform Conference jointly sponsored by the Optical Comm
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The role of macrophage PPARγ acetylation in determining adipose tissue remodeling was discovered for the first time
Time of Update: 2023-02-03
PPARγ synthesis activators thiazolidinediones (TZDs) are an important class of anti-diabetic drugs that inhibit the inflammatory response of macrophages and relieve adipose tissue inflammation in living organisms.
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The venereal disease prevention and treatment team of the Dermatology Hospital won the first prize of the Science and Technology Award of the Provincial Preventive Medicine Association
Time of Update: 2023-02-03
Since 2009, the venereal disease prevention and treatment team of the Dermatology Hospital of Southern Medical University has carried out systematic research on the epidemiology of syphilis and gonorrhea, health education, behavioral intervention strategies, and screening promotion models.
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Liu Chunming's team elucidated the molecular mechanism of albumin accumulation in rice endosperm
Time of Update: 2023-02-03
Recently, Liu Chunming's team from the Institute of Botany, Chinese Academy of Sciences/School of Modern Agriculture, Peking University, found that the accumulation of gliadin in the endosperm of NAC20/26-3 of the NAC20/26 double-knockout mutant nac20/26-3 of flower 11 in rice varieties was slightly reduced, while the accumulation of 16-kD albumin almost disappeared.
