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Cell . . . Insomnia can cause death through the accumulation of reactive oxygen in the intestines.
Time of Update: 2020-07-21
Katherina as we all know, sleep is essential for survival. in the most primitive animals, there is an obvious similar sleep state. Severe sleep deprivation can cause fatal danger, but the underlying c
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What about fever when you're nervous?
Time of Update: 2020-07-21
after the authors artificially activated the DMH – RMR pathway, it was found that the activity of neurons increased and brown fat began to produce heat; unexpectedly, heart rate and blood pressure also increased, which indicated that DMH – RMR pathway can coordinate various physiological responses under stress conditions.
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Meng Bo Soup . . . Gene editing precision "deletes" animal-specific memories - God's scalpel, or Pandora's box?
Time of Update: 2020-07-21
In the above research, Wanyou and Yiming team realized the projection and function specific gene editing in rat brain through CRISPR / cas9 technology, combined with anterograde / retrograde AAV vector and cell marker technology.
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The first clinical evidence: Whether we're asleep or awake, our brains are learning.
Time of Update: 2020-07-21
Recently, a new study published in cell reports provides the first direct evidence that the human brain "plays back" the experience of waking up while sleeping.
Image Source: cell reports jarosiewicz said: "this is the first direct evidence that humans can 'see' playback during rest after learning, which may help consolidate memory.
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ESI Express . . . Hot Papers in neuroscience and behavior, No. 2 of 2020.
Time of Update: 2020-07-21
of the 40 first-time entries, a single article with the highest citation of 69 times was entitled "a review of classification algorithms for EEG based brain computer interfaces: a 10 year update", which was published in the Journal of neural engineering.
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The study revealed that rhythmic genes regulate depression caused by neuroinflammation by controlling chematist factors.
Time of Update: 2020-07-21
researchers from Lin Wenjuan, Key Laboratory of mental health, Institute of psychology, Chinese Academy of Sciences, conducted research on the above problems to explore whether rhythm genes affect neuroinflammation induced depression through regulating inflammatory factors.
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Neuron. "Decision Tree" at the neurotransmitter release site
Time of Update: 2020-07-21
KAESER research team of Harvard Medical School published the article synapse and active zone assembly in the absense of presynaptic Ca2 + channels and Ca2 in the journal Neuron+ The active region is more like a social platform, which determines the location and functional characteristics of synaptic connections, and calcium channels are just VIP users of the platform.
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Space multiscale singularity: the reason behind the diversity of brain rhythms? NSR research paper.
Time of Update: 2020-07-21
Liu Zonghua) recently published in the National Science Review (NSR) Published research papers, pointed out that the real brain structure network has a new singular state spatial multi-scale singular state, its formation is closely related to the symmetry of the network local connection (as shown in the figure below).
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Cell: Bypassing the eyes to implant hallucinations into the brain, the technique gives blind people 'vision'
Time of Update: 2020-07-21
In order to make visual cortex prosthesis better help blind people understand the world, Professor Daniel yoshor started to develop dynamic activated electrodes.
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Molecular Psychiatry: Real Hammer! Another heavy-handed study in the field of the intestinal-brain axis, the driving force behind the onset of depression, was found. Intestinal Weekly.
Time of Update: 2020-07-21
Issue 114: depression; diet, antibiotics, nutrition absorption; obesity, weight loss genes; aspirin, colorectal cancer [junjunjun moment] - advertising space; Jingyun biological health assessment leader of Chinese people click on the picture to see the details.
Intestinal flora can resist or induce colorectal cancer by regulating immune cells!
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The study revealed the neural mechanism that regulates the aggressive behavior of male mice.
Time of Update: 2020-07-21
this study found that the VGluT1 positive neurons in the posterior amygdala of the ventromedial hypothalamic nucleus played an important role in aggressive behavior, and revealed the important function of direct projection from the supracortical structure to the hypothalamus in the process of aggressive behavior gating.
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Pan Bingxing's team made a series of important advances in the study of neural loop mechanisms caused by stress and excessive anxiety.
Time of Update: 2020-07-21
The results showed that the anxiety inducing effect of chronic stress was closely related to the up regulation of presynaptic glutamate transmitter release of dmPFC → BLA PNS.
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Nature's Immunology has a weighty map of the brain's genes that produce poisons.
Time of Update: 2020-07-21
in vitro cell experiments confirmed that asiviscin and ggstop, a GGT inhibitor, could inhibit the activation of microglia induced by fibrin and LPS, increase the level of glutathione, and reduce the production of ROS.
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Nature: (with expert insight) non-classical pathways for spleen-brain regulatory immune function.
Time of Update: 2020-07-21
published in the main issue of nature on April 29, 2020, the paper "brain control of human immune responses amenable to behavioral modulation" published by Qi Hai research group of Tsinghua University, Zhong Yi research group and Hu Ji research group of Shanghai University of science and technology [2] explained the neurochemical and loop mechanism of the regulation of spleen plasma cell production by Shenjing system in humoral immunity.
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The pause key of life? Nature: Scientists find 'hibernating switch' for the first time in mouse brains
Time of Update: 2020-07-21
the artificial activation of these nerve cells can trigger the mice to enter a state similar to hibernation, which greatly reduces the body temperature and energy consumption.
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Cell . . . Qian Yongyou/Li Boxing teamed up to discover the regulatory mechanism of neuronal excitatory steady state.
Time of Update: 2020-07-21
Tsien Laboratory of New York University published the article "nervous activity co OPS LTP machine to drive potassium channel splitting and homeostatic spike Widening" in cell magazine, and found the molecular mechanism of excitatory homeostasis regulation.
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Nature Sub-Journal: Why is the age of the direction of the worse? It turned out to be a "compass" that disturbed the brain.
Time of Update: 2020-07-21
according to their findings, the main source of spatial location errors was that "noise" disturbed the brain's "compass", resulting in inaccurate perception of movement speed.
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Cell . . . Heavyweight released a three-dimensional map of the brains of the third generation of mice.
Time of Update: 2020-07-21
the second edition of 3D Atlas of mouse brain has two fatal shortcomings: (1) transforming 2D structure annotated in coronal field into 3D volume in non coronal plane, resulting in image distortion; (2) lack of cell level resolution required for transcriptomic data on brain neurons.
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EMBO reports . . . The team found that phosphatase PP2A was involved in regulating the pruning of dendrites during neuronal development.
Time of Update: 2020-07-21
In the process of animal development, neuronal maturation often requires selective removal of exuberant or unnecessary nerve branches, which is crucial for the establishment of mature neural circuits
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Science: How does the brain get old? Five billion brain cell connection points reveal life-long changes in the brain.
Time of Update: 2020-07-21
} different synaptic molecules were marked with different colors on brain slices (photo source: reference [3]) a whole brain cross-section of adult mice, with different color dots showing synaptic diversity (photo source: reference [2]; Credit: Seth grant University of) Edinburgh) the researchers used different fluorescent markers to label the proteins expressed in synapses, so as to distinguish the molecular composition of different synapses and the number of different types of synapses.
