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Identifying the risk factors of mild cognitive impairment (MCI) in the elderly with normal cognition-the prodromal stage of dementia can help determine the characteristics of the target group for prevention or intervention strategies for dementia
.
However, not everyone who is diagnosed with MCI will later develop dementia
Identifying the risk factors of mild cognitive impairment (MCI) in the elderly with normal cognition-the prodromal stage of dementia can help determine the characteristics of the target group for prevention or intervention strategies for dementia
In order to study sociodemographic and medical predictors of MCI events and the subsequent MCI process, including continuous MCI diagnosis, cognitive normal classification and the development of dementia, from Columbia University, Alzheimer's disease and brain aging Experts from the institute carried out relevant research and the results were published in the journal Neurology
.
In a community-based cohort, the researchers diagnosed MCI using a published algorithm
.
The diagnosis of dementia is based on clinical consensus
consensus
Of the 2903 cognitively normal participants at the baseline, 752 developed MCI (incidence rate 56/1000 person-years) in an average of 6.
3 (SD 4.
5) years
.
The existence of A POE ε4 and higher medical burden increase the risk of MCI, while more years of education, more leisure activities and higher income reduce this risk
The existence of
The presence of multi-domain MCI, APOE ε4, depressive symptoms and the use of antidepressants increase the risk of progression to dementia
Incidence rate by MCI type
In summary, this community-based study shows that almost half of people diagnosed with MCI were classified as cognitively normal at follow-up
.
The predictors of event MCI are significantly different from the subsequent MCI process; these findings can refine the expectations of the cognitive and functional processes of those who experience MCI
In summary, this community-based study shows that almost half of people diagnosed with MCI were classified as cognitively normal at follow-up
references:
Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population.
Predictors of Incident Mild Cognitive Impairment and Its Course in a Diverse Community-Based Population.
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