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Nature Methods Highlights . . . Transform brain imaging techniques to record more brain neurons.
Time of Update: 2020-07-23
(a) the periodic light pulses are sent to a multiphoton laser scanning microscope to obtain neuron images.
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Nature. How does a fever relieve autism?
Time of Update: 2020-07-23
huh from Harvard University published the title IL-17A promoters society in mouse models of neurodevelopmental in nature In the paper of disorders, we found that IL-17A, a cytokine produced in the inflammatory reaction, can directly affect the neural activity in the brain, thus alleviating the social behavior disorders in mice to a certain extent.
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Why don't you know the darkness of the night during the day? Three new cells have been discovered in Science today to help the brain distinguish between day and night.
Time of Update: 2020-07-23
▎ academic longitude / report today, science magazine published a new study from the Salk Institute: Professor Satchidananda panda found three new types of cells in the human body, and pointed out that they can detect the intensity of light and let the brain construct the rhythm of the biological clock.
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Memory doesn't belong to you! Nature Sub-journal New Study: Collective Memory Changes Individual Memory.
Time of Update: 2020-07-23
the research team pointed out in the paper that when people are asked to remember something, they will replace their actual experience with these collective memories, which shows that these memories are "co constructed" by collective memory and personal memory, which are interwoven with the brain's coding of memory.
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Cell Reports . . . Guo Weixiang's research team reveals a new mechanism for differential regulation of embryonic nerve occurrence and adult nerve.
Time of Update: 2020-07-23
on December 3, 2019, the research group of Guo Weixiang, Institute of genetics and developmental biology, Chinese Academy of Sciences, published an article in cell Reports Magazine: developmental cytogenetic to nuclear translocation of RNA binding protein HuR is required for adult Neurogenesis revealed that the translocation expression of HuR is one of the important regulatory molecular mechanisms of neurogenesis difference between the two stages.
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For the first time, it has been shown that holding hands can synchronize brain waves and relieve pain.
Time of Update: 2020-07-23
in the experiment, a female subject would receive pain stimulation under five different conditions, while her male partner would consider whether there was physical contact: touch + pain (no touch pain) touch + no pain (no touch no pain) no pain (no pain), no pain (no pain), no pain (no pain) (baseline condition) △ the upper part is female and the lower part is male.
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Nature back-to-back article: Scientists find neurons that control both positive and negative emotions.
Time of Update: 2020-07-23
on December 16, 2019, Nature journal Nature Neuroscience published a back-to-back article to reveal the role of SST positive neurons in mPFC brain regions in fear memory and social cognitive function, respectively.
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PNAS: Revealing the biological theory behind economic behavior - how does the brain perceive the value and reward of objects?
Time of Update: 2020-07-23
as early as 2016, Dr. Fabian grabenhorst's research team of Cambridge University pointed out in a study in nature that "the dorsolateral prefrontal cortex of the brain encodes the value of a specific object based on a single neuron, that is, each neuron is stimulated in the process of making economic choices.
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Cell . . . Memory consolidation and forgetting - the battle between two brain waves in non-rapid eye movement sleep.
Time of Update: 2020-07-23
in general, the Ganguly research group found that in the process of memory consolidation and forgetting, slow wave oscillation and δ wave neural activation were different during non REM sleep.
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The Formation of Confirmation Bias in the Brain , Nature - Neuroscience
Time of Update: 2020-07-23
subsequently, they saw their peers' judgments and bets on the same real estate and were asked to submit the final bet - showing their confidence in their initial judgment.
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Current Biology . . . How long meat you eat at night is dopamine in the brain's biological clock center.
Time of Update: 2020-07-23
this study revealed the important role of dopamine type 1 receptor-mediated dopamine signaling pathway in the regulation of eating time, food intake and weight gain in the hypothalamus.
this proves that DRD1 mediated dopamine signaling pathway in the suprachiasmatic nucleus alone is enough to make mice overeat high-fat food and become obese.
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Rewrite the textbook! Science: Scientists may find new synaptic structures.
Time of Update: 2020-07-23
the researchers injected psb0739, a highly selective p2y12r inhibitor, into the cistern cerebellomedullary cistern significantly reduced the cell body connection life of microglia and neurons (about 45%), but did not affect the life span of microglia neuron dendrite contact.
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Nature Sub-Journal: The seahorse circadian clock reveals the role of time in regulating memory recovery.
Time of Update: 2020-07-23
subsequently, the researchers traced the role of BMAL1 in memory retrieval to the hippocampus, and found that the memory retrieval ability of BMAL1 deficient mice was related to the down-regulation of dopamine cAMP signal in hippocampus, and the crosstalk between D1 / d5r and cAMP signal controlled by the hippocampal biological clock affected the time rule of memory retrieval, and BMAL1 mediated Da D1/ D5r and cAMP signal transduction can enhance memory retrieval by targeting GluA1 s845 phosphorylation.
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Advances have been made in the study of molecular mechanisms of ultrasonic nerve regulation.
Time of Update: 2020-07-23
Recently, the ultrasound neuromodulation team of Shenzhen Institute of advanced technology, Chinese Academy of Sciences, and Professor Sun Lei of Hong Kong Polytechnic University have cooperated to prove the important role of mechanical sensitive channel piezo1 in ultrasonic nerve regulation in vitro cell experiment.
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Cell Voice: Where does oxygen perception go after the Nobel prize boom?
Time of Update: 2020-07-23
in the future, we may need to pay more attention to the research of 2-oxoglutarate dependent dioxygenase, epigenetics, mitochondrial signaling, ion channels, peptide synthesis and other in vivo energy metabolism processes in hypoxia inducible factor dependent oxygen perception.
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Cell . . . The nervous system regulates the intestinal resistance to infection.
Time of Update: 2020-07-23
The results showed that the neurons innervating the gut (excluding the neurons embedded in the muscular layer and submucosa) all expressed Nav1.8 (voltage gated sodium channel marking nociceptors) and TRPV1 (encoding TRPV1), nociceptiveion channel that detects heat and capsaicin)。 therefore, the authors used nav1.8-cre/dta and trpv1-dtr, two DRG and vagus nerve ganglion TRPV1 + and CGRP + neurons in mice orally infected with STM, the pathogen resistance of mice decreased significantly.
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Research . . . Unconscious manipulation of visual attention can affect individual risk choices.
Time of Update: 2020-07-23
to explore whether there is a causal relationship between visual attention and risk decision-making, Rao Lilin, a young distinguished researcher from Li Shu research group, Key Laboratory of behavioral science, Chinese Academy of Sciences, led the students to carry out relevant research.
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Xie Xiaofei's group revealed altrual behavior to relieve physical pain.
Time of Update: 2020-07-23
the results showed that the pain level of altruistic group was significantly lower than that of control group in the second tourniquet test, indicating that donating money to disaster areas can relieve pain (Fig. 1).
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Cell . . . Rewrite the understanding! There is a jump conduction in the axon-side clearance.
Time of Update: 2020-07-23
by continuously optimizing the parameters of resistance and capacitance in the model, it is found that the "double cable" mode can better reflect the characteristics of transient voltage conduction on axons.
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Neuron: Find the fateful switch in the retina where the trail is split.
Time of Update: 2020-07-23
} the development and change of sac in retina from embryonic stage to postnatal stage (photo source: reference [1]) how to find the key genes that determine different fate from these differentially expressed genes?