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New research modifies E. coli to deliver antigens to activate immune responses
Time of Update: 2022-08-15
Making 'bacterial robots' overcome two challengesNie Guangjun told reporters that there are two main challenges in the development of oral vaccines: First, vaccines need to overcome the complex digestive tract environment .
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PlasmidMaker: A Universal Automation Platform for Plasmid Design and Construction
Time of Update: 2022-08-15
Image Courtesy: Center for Advanced Bioenergy and Bioproducts Innovation Image: The Illinois Advanced Biofabrication Biofactory (iBioFAB) supports the automated construction of plasmids through a new platform called PlasmidMaker .
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Novel influenza virus hemagglutinin degraders mediated by triterpene PROTAC
Time of Update: 2022-08-15
On May 17 , 2022 , " Journal of Medicinal Chemistry " , an authoritative journal of medicinal chemistry, published the latest research result " Discovery of Pentacyclic Triterpenoid PROTACs as a Clas
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Collaborative study of Xu Guoliang's group reveals that maternal TET3 deficiency mediates female gamete-derived adult diseases
Time of Update: 2022-08-15
This study found that hyperglycemia can reduce the expression level of oocyte DNA dioxygenase TET3 (TET methylcytosine dioxygenase 3), resulting in genomic DNA demethylation disorders in early embryos after fertilization, mainly manifested as the activation of genes related to the insulin secretion pathway Abnormally hypermethylated daughter DNA, and maintain this hypermethylated state until adult pancreatic islets, thereby inhibiting the expression of these genes and inducing offspring to show abnormal glucose tolerance phenotype .
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Scientists discover two new ways to repair blood vessels in tumors
Time of Update: 2022-08-15
"article titleMultiphoton phosphorescence quenching microscopy reveals kinetics of tumor oxygenation during anti-angiogenesis and angiotensin signaling inhibition Tumors send signals that impair normal blood flow, making them difficult to treat with various types of cancer treatments, including radiation, chemotherapy, targeted therapy and immunotherapy .
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The first pig kidney transplanted into a human body, what do scientists think?
Time of Update: 2022-08-15
The team that conducted the experiment reported that kidneys from genetically engineered pigs with human-like immune systems functioned successfully when transplanted into two recently deceased patients .
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A new mechanism of parasitic wasp symbiotic virus bidirectional regulation of host immunity
Time of Update: 2022-08-15
CvBV_28-1 inhibits the proliferation of host blood cells and significantly reduces the number of host blood cellsAt the same time, it was also found that CvBV_28-1 relies on Ca 2+ to produce agglutination reaction, has a classic bacterial clearance function against Gram-positive bacteria, and can enhance the immunity of the host when it is infected by bacteria after being parasitized, thereby improving the parasitic wasp larvae.
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New study identifies genes involved in glioblastoma cell development
Time of Update: 2022-08-15
" A research paper recently published in Nature Communications by a team led by researchers at the Yale University School of Medicine has found a promising way to make brain cancer cells more susceptible to chemotherapy .
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The world's first!
Time of Update: 2022-08-15
status Anhan Technology is an internationally leading high-tech enterprise focusing on the R&D, production and operation of innovative medical devices in the field of digestive tract health.
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The first photo of the black hole at the center of the Milky Way announced that three teachers from Peking University participated in depth
Time of Update: 2022-08-15
The black hole photo of Sgr A* is the result of averaging the different photos extracted by the research team, and finally, for the first time, the "behemoth" hidden in the center of the Milky Way can be presented .
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Scientists detect common fungicide in pregnant women and children
Time of Update: 2022-08-15
" Cell death after treatment of cultured mouse cortical neurons with azoconim and azoconic acid at 1, 10, 100, 1,000 and 10,000 nM concentrations .
" Cell death after treatment of cultured mouse cortical neurons with azoconim and azoconic acid at 1, 10, 100, 1,000 and 10,000 nM concentrations .
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A model that predicts the efficacy of antibacterial phage therapy
Time of Update: 2022-08-15
"Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy Antibiotic resistance is a major public health challenge, but while bacteriophages (viruses that kill bacteria) may be a potential weapon against antibiotic-resistant pathogens, multiple challenges remain .
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Complete daily activities with "ideas" The first clinical trial of brain-computer interface starts
Time of Update: 2022-08-15
Retrieved May 13, 2022, from https:// [1] Synchron Announces Enrollment of First Patient in US Endovascular Brain Computer Interface Study COMMAND in Patients With Severe Paralysis.
Retrieved May 13, 2022, from https:// [1] Synchron Announces Enrollment of First Patient in US Endovascular Brain Computer Interface Study COMMAND in Patients With Severe Paralysis.
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A new breakthrough in concept!
Time of Update: 2022-08-15
Domenig, Inseon Kim, Thomas Hennek, Ferdinand von Meyenn , Ori Bar-Nur. Exclusive generation of rat spermatozoa in sterile mice utilizing blastocyst complementation with pluripotent stem cells .
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Scientists discover a key reason running boosts brain health
Time of Update: 2022-08-15
Rice, 16 May 2022, “Voluntary exercise boosts striatal dopamine release: evidence for the necessary and sufficient role of BDNF” by Guendalina Bastioli, Jennifer C.
Rice, 16 May 2022, “Voluntary exercise boosts striatal dopamine release: evidence for the necessary and sufficient role of BDNF” by Guendalina Bastioli, Jennifer C.
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Science - Translational Medicine: Novel Biomarkers for Triple Negative Breast Cancer
Time of Update: 2022-08-15
Researchers at the Johns Hopkins University School of Medicine have focused on triple-negative breast cancer (TNBC) to uncover key molecular differences between primary and metastatic cancer cells .
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Novel inhaled therapeutic blocks virus replication in lungs
Time of Update: 2022-08-15
". "Because ASO treatment targets a highly conserved part of the viral genome among different variants, it is effective against all SARS-CoV-2 "worrisome variants" in human cells and animal models .
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Beihai Kangcheng ASGCT Annual Meeting Announces First Research Data in Collaboration with UMass Chan School of Medicine
Time of Update: 2022-08-15
The ability to achieve efficient and regulated gene expression across tissues, with the potential to improve efficacy and safety, at doses lower than what is currently used clinically in patients "Our novel second-generation gene therapy vector differs from benchmark vectors in the genetic engineering optimization of SMN1 codons under the control of the endogenous SMN1 promoter.
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Phase II trial of Axsome targeting NMDA receptor depression therapy AXS-05 successful
Time of Update: 2022-08-15
Reference source:Axsome Takes New Approach, Targets NMDA Receptors to Treat Depression CompilationFan DongdongAxsome Therapeutics today announced positive results from the Phase II Ascend clinical trial of major depressive disorder (MDD) therapy AXS-05, published in the American Journal of Psychiatry .
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Nature sub-journal: New portable diagnostic device detects SARS-CoV-2 RNA and antibodies simultaneously
Time of Update: 2022-08-15
Members of Harvard's Wyss Institute for Bioinspired Engineering have created a new point-of-care diagnostic device that integrates the institute's eRapid and SHERLOCK technologies into a single postcard-sized system that simultaneously detects the presence of SARS-CoV-2 in a patient's saliva.
