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Researcher Wang Guanhong published a review article on the prevention and control of mosquito-borne diseases by symbiotic bacteria and gene drive technology in Trends in Genetics
Time of Update: 2022-04-25
Wang Guanhong, a researcher from the Institute of Zoology, Chinese Academy of Sciences, and Jackson Champer, a researcher from the School of Life Sciences, Peking University, published a review article entitled "Symbionts and gene drive: two strategies to combat vector-borne disease" in the internationally renowned journal Trends in Genetics, systematically summarizing the symbiosis The latest research progress of bacteria and gene drive technology in the prevention and control of mosquito-borne diseases .
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The team of Feng Jie from the Institute of Microbiology has made new progress in the mechanism of carbapenem resistance
Time of Update: 2022-04-25
Further research found that the occurrence of high drug resistance was caused by the dynamic and unstable expansion of the multidrug resistance ( MDR ) region including the bla KPC-2 gene mediated by the insertion sequence IS 26 , a mechanism that can help bacteria To evade the attack of carbapenem antibiotics, it is also an important strategy for CRE to escape laboratory in vitro resistance detection, thereby affecting the use and efficacy of antibiotics in clinical applications .
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Wuhan Botanical Garden makes progress in ethnobotanical research on elderberries
Time of Update: 2022-04-25
However, there is still a gap in the currently available data to guide its scientific and rational application, and more investigations are needed on the traditional uses and pharmacological activities of this genus, as well as the mechanism of action and toxicity of the isolated bioactive components , to elucidate its medicinal potential in terms of therapeutic efficacy and safe clinical application .
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Wuhan Botanical Garden makes progress in research on plant litter decomposition
Time of Update: 2022-04-25
Wuhan Botanical Garden graduate student Denis Mburu Njoroge and his collaborators conducted a meta-analysis of published studies around the world to explore the effects of litter diversity and soil animals on decomposition rates .
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Science: Mechanisms of local dopamine release in the brain
Time of Update: 2022-04-25
The classic model for this process, Kaeser explained, is that dopamine neurons receive chemical signals in dendrites in the midbrain, and their cell bodies send action potentials through the axon to the striatum, triggering the release of dopamine that regulates daily behavior .
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Chinese scholars have made research progress in cloud-terminal collaborative security intelligent cloud system
Time of Update: 2022-04-25
However, the intelligent cloud platform faces challenges such as untrustworthy terminal environment, difficult verification of federated learning, unreliable stored data, and difficult retrieval of encrypted data .
The core technologies such as efficient retrieval of state data have formed a series of self-controllable secure and intelligent cloud products (Figure) .
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Cell Rep: Discovery of a new pathway for DNA transfer in the tumor microenvironment
Time of Update: 2022-04-25
"We've shown that DNA is present in these microvesicles with transference, and now we have an excellent platform to assess genetic aberrations," said D'Souza-Schorey, who is also affiliated with the Berthiaume Institute for Precision Health, Boler-Parseghian Center for Rare and Neglected Diseases and Harper Cancer Institute .
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Mechanisms of sleep fragmentation: overexcited neurons
Time of Update: 2022-04-25
A new study led by researchers at Stanford University School of Medicine shows that neurons in the brain's lateral hypothalamus play a key role in sleep deprivation in older mice .
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Chemicals found in broccoli to fight COVID-19 and common cold viruses
Time of Update: 2022-04-25
In addition, the team reported that sulforaphane and remdesivir acted synergistically in several combination ratios to reduce viral burden by 50% in cells infected with HCoV-OC43 or SARS-CoV-2 .
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Suspect COVID-19 is a vascular disease?
Time of Update: 2022-04-25
ACE inhibitor users and ARB users had a lower risk of COVID-19 hospitalization than CCB users (hazard ratio, 0.
This large observational study may suggest that long-term ACE inhibitors or ARBs in hypertensive patients have a lower risk of COVID-19 compared with CCBs .
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Develop operating standards for UV disinfection of N95 masks without compromising performance
Time of Update: 2022-04-25
In a new study published in the National Institute of Standards and Technology's Journal of Research, researchers, with help from federal and private partners, scrutinized Check N95 masks exposed to UV light for traces of the virus, and look for changes in their fiber shape, ability to filter aerosols, and other properties .
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Do human stem cells contain cancer-causing mutations?
Time of Update: 2022-04-25
The research team's breakthrough will help ease the recent controversy over the genetic stability of human embryonic stem cells .
Recent studies have shown that human pluripotent stem cells have been shown to increase the frequency of severe cancer-causing mutations .
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Guangzhou Health Institute builds a new safe and efficient single-base gene editing system
Time of Update: 2022-04-25
Recently, researcher Lai Liangxue of Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, and associate professor Zou Qingjian of Wuyi University collaborated for the first time to fuse adenosine deaminase with transcription activator-like effector (TALE) to develop a Cas9-dependent An off-target novel base editing system TaC9-ABE .
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PNAS discovers new leap in tackling plastic waste problem: a new enzyme
Time of Update: 2022-04-25
The study, published in the Proceedings of the National Academy of Sciences (PNAS), was led by McGeehan, a professor at Montana State University and others, who led an international team of researchers in 2018 to design a natural enzyme that breaks down PET plastic .
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Chinese scholars have made progress in the study of osteoporosis complicated by vascular calcification
Time of Update: 2022-04-25
Fig. The mechanism by which extracellular vesicles derived from aging bone matrix participate in the formation of "calcification contradiction" between bone and blood vessels Under the
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Scientists develop coated probiotics that can effectively enter the human gut
Time of Update: 2022-04-25
In the Nanyang Technological University study, probiotics, gut-friendly lactic acid bacteria, were sprayed with alginate (a carbohydrate derived from brown seaweed) to protect them from the harsh acidic environment of the stomach .
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Hormone-free male contraceptives are 99% effective in preclinical trials and are expected to enter human trials by the end of the year
Time of Update: 2022-04-25
On Wednesday, a team of scientists said they had developed a male oral contraceptive that was 99 percent effective in mice with no apparent side effects, and is expected to enter human trials by the end of this year .
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Chen Xiaolin's group has made new progress in the regulation of the pathogenic mechanism of rice blast fungus by epigenetic modification
Time of Update: 2022-04-25
Nanhu News Network News (correspondent Ren Zhiyong) Recently, the research results of Chen Xiaolin's research group in the State Key Laboratory of Agricultural Microbiology and the School of Plant Science and Technology of our school are titled "MTA1-mediated RNA m6A modification regulates autophagy and is required for infection of the rice blast fungus.
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JAMA: Covid-19 vaccine does not lead to increased risk of pregnancy complications
Time of Update: 2022-04-25
Vaccination against COVID-19 during pregnancy did not lead to pregnancy complications, according to a large registry study published in the Journal of the American Medical Association (JAMA) by the Karolinska Institutet in Sweden and the Norwegian Institute of Public Health.
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Genome issues for plant geneticists looking to improve crop yields
Time of Update: 2022-04-24
But based on his team's surprising findings, Lippman said, having a good gene-editing candidate is not enough to predict the outcome of planned alterations, "and the lack of predictability in the context of duplicated genes does require a lot of effort in designing crops.
Lippman's team introduced the same clv3 gene mutation in tomato, tobacco, cherry and petunia .
