Under the support of the National Natural Science Foundation of China (Grant Nos.
Osteoporosis and vascular calcification are two pathological phenomena that seriously threaten the health of middle-aged and elderly people
The team found that bone cells can secrete bone matrix extracellular vesicles (B-EVs), which are released into the bone marrow cavity during bone resorption and transported to the blood vessel wall tissue through the blood circulation; derived from the elderly population (67-73 years old) B-EVs can significantly promote the adipogenic differentiation of bone marrow mesenchymal stem cells and the osteogenic transdifferentiation of vascular smooth muscle cells; B-EVs derived from the elderly population were injected into young or old children through the marrow cavity.
The team conducted in-depth research on the role and mechanism of B-EV in bone metabolism and vascular calcification, providing new ideas for the prevention and treatment of senile osteoporosis and vascular calcification
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
