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The team of Professor Xia Ningshao of our hospital revealed the dual effects of S protein variation on the species tropism and neutralization escape of 2019-nCoV
Time of Update: 2022-04-26
Among them, the mutation of spike protein S has the most significant impact on the virus functional phenotype and vaccine response neutralizing antibodies, and is also the focus of current research on new coronavirus mutation .
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"Catalogue of Vascular Plants in the Tianshan Mountains" published
Time of Update: 2022-04-26
TRS_Editor A{margin-top:0px;margin-bottom:15px;line-height:2;font-family:;font-size:12pt;}</> A few days ago, with the strong support of the Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, the Xinjiang Botany Society organized the "Tianshan Vascular Plant Directory" jointly compiled by experts from the Xinjiang botany community for publication .
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Zhan Xiaowei's group and collaborators reduce the energy disorder of perovskite solar cells through chelation
Time of Update: 2022-04-26
The intermolecular van der Waals interaction of FP-C8 and the chelation with the perovskite surface effectively reduce the energy disorder of the electron transport layer and its interface with the perovskite, and improve the efficiency and stability of the device .
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Shenzhen Graduate School Pan Feng's group established a screening method for low-dimensional materials based on graph theory and discovered a series of one-dimensional materials
Time of Update: 2022-04-26
Through the graph isomorphism comparison method in mathematical graph theory, the material structure can be classified, and the classification results can reflect the topological characteristics of different structures .
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Professor Xia Ningshao's team revealed the dual effects of S protein variation on SARS-CoV-2 species tropism and neutralization escape
Time of Update: 2022-04-26
The COVID-19 pandemic caused by the new coronavirus poses a serious threat to global public health and socioeconomic development . The genomic variation of 2019-nCoV may affect virus transmission, p
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Guangzhou Health Center establishes and analyzes human 8-cell stage embryo-like cells in vitro
Time of Update: 2022-04-26
The researchers used single-cell sequencing technology to analyze and determine the relationship between 8CLC and human The high similarity of 8-cell stage embryos delineates key molecular events and gene regulatory networks of the transformation process, and further evaluates the differentiation capacity of 8CLCs .
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Wuhan Institute of Virology/National Virus Resource Bank has made new progress in the identification of tick-derived promoters and the research on tick cell line transfection system
Time of Update: 2022-04-26
Establishing a plasmid transfection method for tick cell lines and efficiently driving the expression of exogenous proteins is of great significance for the study of the interaction mechanism between tick-borne viruses and key proteins and factors in tick cells, and for analyzing the infection and replication mechanism of viruses in tick cells .
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Professor Qian Feng's research group from Shanghai Jiaotong University discovered a new mechanism of asthma regulation
Time of Update: 2022-04-26
On March 25, 2022, Professor Qian Feng's research group from the School of Pharmacy, Shanghai Jiao Tong University published a long article titled AMFR drives allergic asthma development by promoting alveolar macrophage in the Journal of Experimental Medicine (IF=14.
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Transfer: [Frontiers of Science and Technology] Wuhan University Song Zhiyin and other teams discover a new mechanism of mitochondrial DNA release
Time of Update: 2022-04-26
Thus, our findings reveal a critical role for Sam50 in maintaining hepatocyte mitochondrial membrane integrity and mtDNA stability, and reveal that Sam50 depletion-induced cardiolipin externalization is a novel signal released by mtDNA that controls mtDNA-dependent innate immunity .
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Two articles by Zhejiang University scholar PNAS and others: Revealing a new mechanism for the division of cellular DNA polymerase functions
Time of Update: 2022-04-26
On March 15 , 2022 , PNAS , the Proceedings of the National Academy of Sciences, published online the research paper Global genomic instability caused by reduced expression of DNA polymerase ε in yeast in which Zhang Ke , a distinguished researcher at the Institute of Microbiology, School of Life Sciences, Zhejiang University, is the first author .
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Wuhan Botanical Garden has made new progress in the study of lotus color decline
Time of Update: 2022-04-25
In order to explore the mechanism of lotus color decline and improve the ornamental quality of lotus, the lotus germplasm resources and genetics group of Wuhan Botanical Garden, Chinese Academy of Sciences has carried out research on the mechanism of lotus color decline .
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Chinese scholars have made progress in the study of topologically protected quantum entanglement
Time of Update: 2022-04-25
The preparation of topologically protected quantum entangled states is of great significance to the development of large-scale integrated quantum devices and the study of new topological physics and phenomena of quantum systems .
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Nat Biotech: New implantable stent more effective than CAR-T therapy
Time of Update: 2022-04-25
First author Pritha Agarwalla, a postdoctoral researcher in the Joint Department of Biomedical Engineering, said: "Our MASTER technology transfers the tedious and time-consuming steps of activation, reprogramming and amplification to the patient .
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The research results of the research group of Associate Professor Yan Junchi of Shanghai Jiaotong University were awarded the most influential paper in AAAI21
Time of Update: 2022-04-25
The detection effect on the remote sensing image shows that R3Det can accurately locate the aircraft positions in different directions in the airportResearch progress of the research groupIn the past three years, Associate Professor Yan Junchi's research group has successively published a series of papers on directed visual object detection at ICCV19, ECCV20, AAAI21, CVPR21, ICML21, NeurIPS21, and IJCV22, the top artificial intelligence conferences .
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Feedback links between plasticity of bird migration strategies and population dynamics
Time of Update: 2022-04-25
Recently, the team of Professor Zhang Zhengwang of Beijing Normal University used more than ten years of waterfowl monitoring data to start from the loss of migratory birds during the migratory stop, and for the first time revealed the feedback link between the migration strategies and population dynamics of birds .
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A new study reveals why HIV persists in human tissues even after antiretroviral therapy
Time of Update: 2022-04-25
Elahi and his team found that in AIDS patients, killer T cells -- a type of white blood cell responsible for recognizing and destroying virus-infected cells -- were almost devoid of a protein called CD73 .
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The latest paper from Nature Communications of Sichuan University: Molecular mechanism of ligand entry into Sigma-1 receptor pathway
Time of Update: 2022-04-25
The crystal structure of the human sigma-1 receptor (hσ1R) published in 2016 (Figure 1 left) shows that the σ1R structure is in the form of a homotrimer, each monomer contains an amino-terminal primary transmembrane helix (α1), a middle The β-barrel containing the ligand binding site and the V-shaped double helix bundle (α4/α5) with the carboxyl terminus close to the membrane .
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Cell: Improving cellular responses and mixed immunity
Time of Update: 2022-04-25
"Vaccines alone are very good at preventing disease; they just don't produce as diverse an immune response as a post-vaccination infection," said Marion Pepper, an associate professor in Washington University's Department of Immunology who led the study.
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Fang Fang's research group from the School of Psychological and Cognitive Sciences uses non-invasive neuromodulation technology to enhance human visual learning ability and visual cortex plasticity
Time of Update: 2022-04-25
9" >Recently, Fang Fang’s research group from the School of Psychology and Cognitive Sciences of Peking University has published research papers in Brain Stimulation , a top journal in the field of neuromodulation , and found that transcranial electrical stimulation technology can effectively improve the performance of visual perception learning .
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Nature Cancer: Chinese scholars have discovered a CAR-T cell that inhibits solid tumor cells and is not toxic to healthy tissues
Time of Update: 2022-04-25
Penn researchers found that CAR-T cells targeting the tumor antigen CDH17, a cell-surface marker expressed on NETs and GICs, but also found in healthy tissues, eliminated GICs in multiple preclinical models, Also, there was no toxicity to normal tissues in many mice, including the small intestine and colon .
