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Creating the first graphical pan-genome map of sheep based on HiFi sequencing
Time of Update: 2022-04-27
As an important scientific research team in the study of animal genomes in China, Professor Jiang Yu's team from Northwest A&F University will publish the first high-quality reference genome Saanen_v1 of Saanen dairy goat in 2021 in Genetics Selection Evolution, a top journal in the field of animal genetics and breeding 1 , the study used high-depth Pacbio sequencing and Hi-C-assisted assembly technology, and its Contig N50 reached 46Mb .
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The National Natural Science Foundation of China Regional Innovation and Development Joint Fund "Evolution and Driving Mechanism of Wetland Ecological Pattern in Dongting Lake" held a project kick-off meeting and implementation plan demonstration meeting
Time of Update: 2022-04-27
On March 21, the Institute of Subtropical Agroecology, Chinese Academy of Sciences organized the launch meeting and implementation plan demonstration meeting of the National Natural Science Foundation of China Regional Innovation and Development Joint Fund "Dongting Lake Wetland Ecological Pattern Evolution and Driving Mechanism" project .
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Yang Weiwei teamed up to discover a new function of pyruvate dehydrogenase in tumor immune escape
Time of Update: 2022-04-26
TRS_Editor A{font-family:;font-size:12pt;}</> On March 21, the international academic journal Nature Metabolism published online the research group of Yang Weiwei and Zhao Yun from the Center for Excellence in Molecular and Cell Science (Institute of Biochemistry and Cell Biology), Chinese Academy of Sciences, and the team of Yao Feng from the Chest Hospital Affiliated to Shanghai Jiaotong University.
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Guangzhou Health Center has made progress in the research of nucleoside anti-Zika virus drugs
Time of Update: 2022-04-26
Recently, Zhang Jiancun's research group from Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, and Yuan Jie's research group from Sun Yat-Sen University have designed and synthesized a series of new nucleoside inhibitors for ZIKV, and obtained candidate drugs that can inhibit ZIKV .
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The macro-distribution pattern and climate-driven mechanism of β-diversity of Lauraceae in my country revealed by Chengdu Institute of Biology
Time of Update: 2022-04-26
Liao Ziyan of Chengdu Institute of Biology, Chinese Academy of Sciences, under the guidance of researcher Pan Kaiwen and associate researcher Zhang Lin, and researchers from many research institutions at home and abroad, took Lauraceae as the research object , a key family of evergreen broad-leaved forests in China.
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Shanghai Jiaotong University Xiong Liqin's research group published the latest results: transformation of silk through diet
Time of Update: 2022-04-26
Recently, the research group of Associate Professor Xiong Liqin, appointed by the Dean of Biomedical Engineering of Shanghai Jiaotong University, published the title "Dual-Performance Optimized Silks from Ultra-Low Dose Polymer Dots Feeding and Its Absorption, Distribution and Excretion" in Advanced Fiber Materials, a new journal of SCIE.
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Chinese scholars have made progress in the study of dissipation-time uncertainty
Time of Update: 2022-04-26
By tracking the state of ions in time and analyzing energy flow, entropy production and entropy flow, the experiment demonstrates the limitation of entropy flow on the completion rate of a process in the non-equilibrium physical process of quantum systems, confirming the "dissipation-time uncertainty relationship" (picture) .
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Personalized cancer vaccine development company receives $17 million in financing for clinical treatment of liver cancer
Time of Update: 2022-04-26
GNOS-PV02, developed by GT-EPIC platform, is a neoantigen vaccine based on DNA plasmid delivery .
References:[1] Geneos Therapeutics Secures $17 Million in Series A2 Financing to Advance Personalized Cancer Immunotherapy Platform.
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Researcher Wu Haoxing's team published a hot paper in Angew. Chem.: Revealing the general design strategy and mechanism of near-infrared bioorthogonal probes
Time of Update: 2022-04-26
Recently, the team of researcher Wu Haoxing from the Clinical Magnetic Resonance Research Center of West China Hospital of Sichuan University and the team of Professor Liu Xiaogang of Singapore Unive
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Science publishes the research results of the cooperation between Professor Yan Jianbing's team and China Agricultural University
Time of Update: 2022-04-26
It was further found that in the process of maize domestication and improvement, the upstream non-coding region of the gene was significantly selected, resulting in a decrease in gene expression, which in turn increased the number of rows and grains per ear, and finally increased yield .
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The team of Professor Gao Feng and Professor Xianghui Yu isolated anti-HIV-1 broad-spectrum neutralizing antibodies from a rhesus monkey model, and revealed that such antibodies mature into...
Time of Update: 2022-04-26
The research team of Professor Gao Feng and Professor Yu Xianghui from the School of Life Sciences of Jilin University took the rhesus monkey animal model with the longest reported infection time as t
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Revolutionary breakthrough: human totipotent stem cells
Time of Update: 2022-04-26
Researchers from the Chinese Academy of Sciences and Shenzhen BGI Life Science Institute and other institutions used somatic cell induction technology to induce and culture human totipotent stem cells similar to fertilized eggs for 3 days .
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Shanghai Jiaotong University Wei Dongqing's team discovered Transformer-based peptide-HLA class I binding prediction and vaccine neoantigen sequence design
Time of Update: 2022-04-26
The AOMP program developed based on TransPHLA can be used for vaccine design, which can automatically optimize mutant peptides to search for mutant peptides with higher affinity to the target HLA and high homology to the source peptide .
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Gene Editing 2.0 Upgraded!
Time of Update: 2022-04-26
Recently, Caixia Gao's research group and collaborators from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences published research results, and successfully established a more efficient and widely applicable new guided editing system ePPE ( Engineered Plant Prime Editor ) in plants .
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The Institute of Zoology Collaborated to Discover the Mechanism of PCBP2 Regulation of cGAS-DNA Phase Transition
Time of Update: 2022-04-26
In terms of the regulatory mechanism, the researchers found that PCBP2 can significantly inhibit the phase separation and enzymatic activity of cGAS-DNA in vitro .
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Zeng Yi's team revealed that Procr as a functional receptor regulates stemness maintenance and self-renewal of mammary stem cells
Time of Update: 2022-04-26
TRS_Editor A{font-family:;font-size:12pt;}</> On March 22, the international academic journal Cell Reports published online the collaborative research results "Procr functions as a signaling receptor and is essential for the maintenance and self-renewal of mammary stem cells” .
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Shanghai Jiaotong University Shen Juntai's team revealed the distribution of matter in the Milky Way with a gas dynamic model
Time of Update: 2022-04-26
Comparison with mainstream cosmological simulationsThe research team has given the most accurate rotation curve (which directly traces the mass distribution) of the Milky Way from the center of 100 parsecs to the vicinity of the sun based on the gas dynamics model .
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Chinese scholars have made progress in the study of the pathogenic mechanism of Clostridium difficile infection
Time of Update: 2022-04-26
The related results are titled "TFPI is a colonic cryptic receptor for TcdB from hypervirulent clade 2 C.
Then, through biochemical and cytological experiments, TFPI molecule was identified and verified as a key receptor for mediating the entry of TcdB of the hypervirulent clade C.
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Demystifying the pathogenesis of aortic dissection from the perspective of single cells——The research results of Zhang Tao's research group from the Department of Vascular Surgery, Peking University People's Hospital are published in an authoritative academic journal
Time of Update: 2022-04-26
The research group of Zhang Tao from the Department of Vascular Surgery of Peking University People's Hospital, the research group of Professor Wang Li of the State Key Laboratory of Cardiovascular Diseases of Fuwai Hospital, Chinese Academy of Medical Sciences, and the research group of Professor Guo Wei of the First Medical Center of the People's Liberation Army General Hospital and the Center of Vascular Surgery of the PLA are in Theranostics Journal (IF 11.
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Advances in research on medicinal plants of the Dai nationality in the ginger family
Time of Update: 2022-04-26
The above research results reveal that the alcoholic extract of the root of Hainan Mountain ginger root, a traditional Dai medicine for food and medicine, is rich in curcumin, curcumin derivatives, flavonoids, polyphenols and their hybrid compounds, which is a good adjuvant treatment for ulcerative colitis.
