Shanghai Jiaotong University Xiong Liqin's research group published the latest results: transformation of silk through diet

Recently, the research group of Associate Professor Xiong Liqin, appointed by the Dean of Biomedical Engineering of Shanghai Jiaotong University, published the title "Dual-Performance Optimized Silks from Ultra-Low Dose Polymer Dots Feeding and Its Absorption, Distribution and Excretion" in Advanced Fiber Materials, a new journal of SCIE.

As a natural fiber, silk has good biocompatibility and biodegradability, and has a wide range of applications in the field of modern biomedicine

Conjugated polymer nanoprobes (Pdots) are a new type of fluorescent probes developed in recent years

Figure 1.

Figure 2.

Analysis of the secondary structure of silk found that Pdots used their own functional groups to interact with silk fibroin, which hindered the transition of the conformation of silk fibroin from random coil to β-sheet structure, so the content of β-sheet in silk fibroin decreased.

Figure 3.

The strong fluorescent silk retains the excellent biocompatibility of natural silk, and has broad application prospects in cell scaffold imaging (Fig.

In this study, the conjugated polymer nanoprobes were used for the first time in the preparation of strong fluorescent silk by modifying silk through diet

Figure 4.

Figure 5.

Li Jingru, a doctoral student at the School of Biomedical Engineering, Shanghai Jiao Tong University, is the first author of this article, and Xiong Liqin, a long-term associate professor, is the corresponding author

Original information:

Jingru Li, Yuqiao Li, Shuting Lu, Juxiang Zhang, Chunfu Zhang, Liqin Xiong*, Dual?Performance Optimized Silks from Ultra?Low Dose Polymer Dots Feeding and Its Absorption, Distribution and Excretion in the Silkworms.

Xiong Liqin, associate professor and doctoral supervisor of the Dean of Biomedical Engineering, Shanghai Jiao Tong University

author:

Li Jingru

Contributing unit:

School of Biomedical Engineering