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Researchers find reason why Omicron gene variant causes less severe disease
Time of Update: 2022-02-17
The Omicron variant of SARS-CoV-2 causes less severe disease than the Delta virus, although it evades immune protection more easily through vaccination and previous infection .
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From January 16th to 17th, we went to the mountains and seas, and Wei Ai came to Ai Wei Lan Sanya's first Tongyan Master Ceremony
Time of Update: 2022-02-17
As an important part of Aiweilan's brand planning and medical education, Aiweilan Sanya Aesthetics Center is located in the beautiful sailing port of the Banshan Peninsula.
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Science sub-journal: New breakthrough in pancreatic cancer treatment!
Time of Update: 2022-02-17
In this latest study, researchers at the San Rafael Institute of Science believe that breaking the sugar barrier around tumor cells by improving CAR-T cell activation and alleviating CAR-T cell exhaustion is the key to overcoming solid tumor resistance to CAR-T cells.
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Chengdu Institute of Biology developed a new method for 2D-1D-2D mass spectrometry imaging
Time of Update: 2022-02-17
The team of researcher Zhou Yan of Chengdu Institute of Biology, Chinese Academy of Sciences has successfully developed a 2D-1D-2D mass spectrometry imaging technology based on line sampling mass spectrometry, which can be used for imaging analysis of large-scale and uneven biological samples .
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'Left-handers' tighten control over embryonic development
Time of Update: 2022-02-17
Experiments led by Aryeh Warmflash's lab at Rice University and postdoctoral researcher Lizhong Liu have visualized for the first time the mechanisms by which Nodal and Lefty interact to determine the future body planning of mammalian embryos .
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[Research News] Professor Yang Xiangliang and Professor Li Zifu, School of Life, Huazhong University of Science and Technology: Rational design of nano-drugs based on the five principles to eradicate tumors...
Time of Update: 2022-02-17
(Correspondent Deng Qingyuan) On January 26, 2022, Professor Yang Xiangliang and Professor Li Zifu from the School of Life Science and Technology and the National Nanomedicine Engineering Technology Research Center of our school published an article entitled "Rational design of A review of nanotherapeutics based on five features principle for potent elimination of cancer stem cells” .
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[School News] Zhang Zhuqing's research group from the School of Life Sciences has made new progress in the in vitro liquid-liquid phase separation (LLPS) database of proteins
Time of Update: 2022-02-17
In September 2019 , Zhang Zhuqing's research group from the School of Life Sciences released the Liquid-liquid phase separation database ( LLPSDB ) in vitro, which included, classified and annotated the reported proteins with LLPS in vitro and the detailed experimental conditions for the occurrence of phase separation.
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The Lancet: Rare diseases are more common than previously thought
Time of Update: 2022-02-17
A rare respiratory disorder called primary ciliary dyskinesia (PCD) is more common than previously thought, according to a large data analysis led by Indiana University School of Medicine professor Benjamin Gaston, MD .
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To create a "replacement" of human organs, functional compatibility is still a problem
Time of Update: 2022-02-17
——Pan Dengke, deputy head of the Xenotransplantation Group of the Chinese Medical Association Organ Transplantation Branch, and deputy director of the Institute of Organ Transplantation, Sichuan Provincial People's Hospital◎Our reporter Wu Chunxin and Luo ChaoshuCorrespondent Wang XiaoxiaoOn January 20, local time, the American Journal of Transplantation published a paper by researchers at Alabama State University, revealing that they successfully completed a trial of transplanting a pair of gene-edited pig kidneys to a brain-dead patient last September.
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The genetic code for 10% longer life in humans
Time of Update: 2022-02-17
Co-lead author Dr Nazif Arik (UCL Institute for Healthy Ageing) said: "We have found from extensive previous research that inhibiting certain genes in cells involved in making proteins can prolong the development of yeast, worms and worms.
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Bacterial indoles as multifunctional modulators of complex enterotoxicity in Klebsiella oxytocins
Time of Update: 2022-02-17
PXR is a ligand-activated host nuclear receptor that plays an important role in exogenous detoxification (13) PXR also modulates intestinal inflammatory responses by binding to microbe-specific indoles (12).
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Two metal ion-dependent enzymes as potential antiviral targets for human herpesviruses
Time of Update: 2022-02-17
SummaryMost drug development efforts targeting herpes viruses have focused on nucleoside analogs targeting viral DNA polymerases that have been associated with dose-limiting toxicity and/or narrow-spectrum activity .
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A new PNAS study questions the primacy of meat in early human evolution
Time of Update: 2022-02-17
Andrew Barr, lead author of the study and assistant professor of anthropology at George Washington University: "This astounding direct evidence that early humans ate meat further confirms the idea that there was a meat-eating explosion 2 million years ago .
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George Church's team publishes cover article: Safely implanting therapeutic genes into the human genome
Time of Update: 2022-02-17
Now, a collaboration of researchers at Harvard's Wyss Institute for Biologically Inspired Engineering, Harvard Medical School (HMS), and ETH Zurich, Switzerland, has developed a computational method to identify therapeutic genes with significantly higher safety and A GSH site that is persistently expressed in many cell types .
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Nature Aging: Blood protein may be key to healthy longevity
Time of Update: 2022-02-17
Drugs that lower blood levels of these proteins could allow the average person Live longer and healthier lives than those born with low levels of LPA and VCAM1 .
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The CinB nuclease of wNo-Wolbachia is sufficient to induce cytoplasmic incompatibility in Drosophila
Time of Update: 2022-02-17
These results suggest that highly differentiated CinB nucleases can induce CI and that rescue of cognate CifA factors is a common feature of cibWolbachiaCI system, cia has no strict requirements for male CI induction .
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"Cell" The magic molecule that corrects protein misfolding
Time of Update: 2022-02-17
Now, a new study shows that a drug commonly used to treat cystic fibrosis ensures that the protein has enough time to bend into shape by directly helping the protein folding process bind CFTR .
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Does an individual's walking speed affect their heart failure risk?
Time of Update: 2022-02-17
Brisk walking for less than 1 hour per week reduces the risk of heart failure in the same way as average or leisure walking for more than 2 hours per week .
The association of walking pace and incident heart failure and subtypes among postmenopausal women .
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Nat Commun He Aibin's research group reveals the epigenetic inheritance of the origin of hematopoietic stem cells..
Time of Update: 2022-02-16
In order to explore the scientific question of how multi-dimensional epigenetic levels in mammalian embryos regulate the occurrence of HSCs, this study broke through the technical bottleneck of small-scale cell detection and applied a small-scale cell sisHi-C (small-scale in situ Hi-C) technology3 and The small-cell itChIP-seq (indexing and tagmentation-based chromatinimmunoprecipitation sequencing) technology4 developed by He Aibin's team in 2019 detected chromatin interaction structure, histone modification and transcription factor binding maps in hundreds of cells .
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New Strategies to Fight Viral Infections
Time of Update: 2022-02-16
Their experiments showed that inhibiting various components of a network of proteins known as mechanistic targets of the rapamycin (mTOR) pathway could prevent RSV from replicating in human cells .
Since some of the drugs shown in this study that inhibit mTOR components and block viral replication are already approved by the U.
