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How does weight affect the risk of death in excessive drinkers?
Time of Update: 2022-02-18
The researchers analyzed mortality risk data for drinkers and nondrinkers, using the Centers for Disease Control and Prevention (CDC) classification to define "underweight," "normal weight," "overweight," and "obese .
"Further research is needed on how being underweight contributes to mortality in people who drink excessively .
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Yang Weiwei's group discovered a new function of the metabolite pyruvate in DNA damage response
Time of Update: 2022-02-18
TRS_Editor A{font-family:;font-size:12pt;}</> On January 20, the international academic journal Advanced Science published online the latest research results of Yang Weiwei's research group at the Center for Excellence in Molecular and Cellular Science (Institute of Biochemistry and Cell Biology), Chinese Academy of Sciences, "Pyruvate facilitates FACT-mediated γH2AX loading to chromatin and promotes.
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Reinterpreting our brain's physical map
Time of Update: 2022-02-18
A recent research paper by Professor Kazumichi Matsumiya from the Graduate School of Information Sciences at Tohoku University in Japan reveals that the human body relies on multiple maps selected based on the motor system .
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PNAS: In visual memory, size matters
Time of Update: 2022-02-18
Sharon Gilaie-Dotan, PhD, from Bar-Ilan University's School of Optometry and Visual Sciences and Gonda (Goldschmied) Multidisciplinary Brain Research Centre, has led a new study that sought to determine how large the Whether images are easier to remember than small images .
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The research group of Qian Zhigang and Xia Xiaoxia of Shanghai Jiaotong University cooperated to establish a production platform for efficient secretion of spider silk protein
Time of Update: 2022-02-18
Recently, the research group of Qian Zhigang and Xia Xiaoxia from the School of Life Science and Technology of Shanghai Jiao Tong University published a paper entitled Secretory production of spider silk proteins in metabolically engineered Corynebacterium glutamicum for spinning into tough fibers in the well-known journal "Metabolic Engineering" in the field of metabolic engineering and synthetic biology.
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De novo mutations may affect male fertility
Time of Update: 2022-02-18
Taken together, the results of this study suggest that de novo mutations may play a key role in severe male infertility and are new candidate genes that affect human fertility .
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"Nature Medicine" Silencing a gene accidentally found clues to the treatment of ALS
Time of Update: 2022-02-18
By studying patients' brain and spinal cord tissue, the researchers found that the drug silenced FUS throughout the nervous system and reversed the toxicity of FUS and other disease-related proteins .
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"Cell" surprised to discover a neuron that controls 'walking'
Time of Update: 2022-02-18
George Mentis, a neurologist at Columbia University, said he studies the circuits that control walking and is working to find new treatments for people with ALS, SMA and spinal cord injuries .
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GHDDI announces the progress of self-developed new crown oral drug: it can effectively inhibit virus replication and is expected to enter the clinic in the second half of 2022
Time of Update: 2022-02-17
On January 25, the Global Health Drug Research and Development Center (GHDDI) announced that its preclinical drug candidate molecule GDI-4405 targeting the novel coronavirus 3CL protease is accelerating multiple clinical trial applications and drug production.
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Neuron: The neural circuit mechanism of early stroking to promote pleasant social interaction
Time of Update: 2022-02-17
The study found that early developmental social touch promotes social interaction behavior and positive preference for the touch environment in mice, and this long-term effect is mediated by a peptidergic neuronal pathway, the midbrain periaqueductal Tachykinin 1 (Tac1+) neurons in lateral and ventrolateral periaqueductal gray (l/vlPAG) act as relay stations to transmit tactile information and increase paraventricular nucleus (PVH) induction of labor in the hypothalamus The firing frequency of Oxytocin neurons promotes social interaction behaviors and positive emotions .
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[Research News] The team of Professor Zhu Bin, Professor Liu Wei and Professor Wang Chenhui from the School of Life of Huazhong University of Science and Technology discovered that DOCK2 regulates antifungal immunity...
Time of Update: 2022-02-17
(Correspondent Ma Xiaojian) On January 26 , Professor Zhu Bin, Professor Liu Wei and Professor Wang Chenhui from the School of Life Sciences of Huazhong University of Science and Technology jointly published a research paper entitled " DOCK2 regulates antifungal immunity by regulating RAC GTPase activity " in the authoritative journal Cellular Molecular Immunology .
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Research progress on anaerobic digestion of fruits and vegetables with municipal sludge in Chengdu Biological Institute
Time of Update: 2022-02-17
Lv Qingyang and researcher Yan Zhiying, Jiang Xinru, a member of the pollution biological control project team of the Chengdu Institute of Biology, Chinese Academy of Sciences, adopted the synergistic anaerobic digestion of fruit and vegetable waste with high carbon and nitrogen ratio and municipal sludge, and the unit organic matter gas production rate of the substrate increased.
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Unexpected new discovery: Breathing is the master clock of the sleeping brain!
Time of Update: 2022-02-17
Neuroscientists at LMU have shown that breathing coordinates neuronal activity throughout the brain during sleep and rest .
"This mechanism mediates the coordination of sleep-related activity in these brain regions, which is critical for memory consolidation, and provides the means for co-regulation of cortical-hippocampal circuit synchronization dynamics .
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To create a "replacement" of human organs, functional compatibility is still a problem
Time of Update: 2022-02-17
——Pan Dengke, deputy head of the Xenotransplantation Group of the Chinese Medical Association Organ Transplantation Branch, and deputy director of the Institute of Organ Transplantation, Sichuan Provincial People's HospitalOn January 20, local time, the American Journal of Transplantation published a paper by researchers at Alabama State University, revealing that they successfully completed a trial of transplanting a pair of gene-edited pig kidneys to a brain-dead patient last September.
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Mechanism of interaction between nuclease Dna2 and single-stranded DNA-binding protein RPA during DNA replication and repair
Time of Update: 2022-02-17
On January 18 , 2022 , Qi Zhi's laboratory of Peking University Center for Quantitative Biology, Niu Hengyao 's laboratory of Indiana University, and Grzegorz Ira 's laboratory of Baylor College of Medicine published in the journal Nature Communications the title Deciphering the mechanism of processive ssDNA digestion by the Dna2 - Article on RPA ensemble .
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Li Lei's group from the School of Life Sciences discovered a new mechanism for copper homeostasis to regulate Arabidopsis leaf senescence
Time of Update: 2022-02-17
9" >On January 12, 2022, Li Lei's research group from the School of Life Sciences of Peking University published a research paper titled " The PCY-SAG14 phytocyanin module regulated by PIFs and miR408 promotes dark-induced leaf senescence in Arabidopsis " in the journal PNAS online .
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"JAMA" "Personal Genome Testing" Industry Alarm: Most "pathogenic" genetic variants have low risk of disease
Time of Update: 2022-02-17
In the study, the researchers addressed this question by searching large-scale DNA sequencing data from 72,434 individuals to find 37,780 known variants, and then scanning each individual's health records for corresponding disease diagnoses .
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How to mend a broken heart?
Time of Update: 2022-02-17
In a Stem Cell study published in January, researchers from Osaka University reported that heart cells from a patient with a hereditary heart disease called arrhythmogenic cardiomyopathy contracted incorrectly in the lab, which replaced the mutated gene responsible for repairing the defect.
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Nuclear envelope is key to fighting cancer -- broccoli compound induces yeast cell death and autophagy
Time of Update: 2022-02-17
"We found that the chemical compound DIM is able to induce a novel biological activity that disrupts the nuclear envelope of fission yeast," said Ueno, an associate professor at the Hiroshima Center for Healthy Aging Research .
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The latest research from China CDC and Nankai University found that Omicron mutation may originate in mice
Time of Update: 2022-02-17
Recently, the Journal of Biosafety and Biosecurity published online an analysis paper on the Omicron variant by the team of Academician Xu Jianguo from the Chinese Center for Disease Control and Prevention and Professor Sun Yamin from the Institute of Public Health and Health of Nankai University.
