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(CorrespondentDeng Qingyuan) On January 26, 2022, Professor Yang Xiangliang and Professor Li Zifu from the School of Life Science and Technology and the National Nanomedicine Engineering Technology Research Center of our school published an article entitled "Rational design of A review of nanotherapeutics based on five features principle for potent elimination of cancer stem cells”
Cancer stem cells (CSCs), also known as tumor-initiating cells or tumor-regenerative cells, are the culprits of tumor initiation, progression, drug resistance, metastasis and recurrence
At the China Pharmaceutical Preparation Conference in 2012, the team of Prof.
In 2021, Professor Yang Xiangliang and Professor Li Zifu were invited to summarize the various tumor-targeted nano-delivery systems and adjuvant therapies designed by our team based on the "Five Principles" based on the "Five Principles", which can effectively eradicate tumor stem cells, including Nanogels adapted to hydrophobicity, tumor stem cell-derived microparticles with customized softness and hardness, exosome biomimetic porous silicon nanoparticles effluxed from tumor cells, and hyperbaric oxygen therapy that can endow the marketed nanomedicines with the "Wu De" characteristics
Rational design of nanomedicines based on the "five-get" principle to effectively eliminate cancer stem cells
Zhang Zhijie and Deng Qingyuan, doctoral students of the
Paper link: https://pubs.
