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    Home > Biochemistry News > Biotechnology News > Phase II trial of Axsome targeting NMDA receptor depression therapy AXS-05 successful

    Phase II trial of Axsome targeting NMDA receptor depression therapy AXS-05 successful

    • Last Update: 2022-08-15
    • Source: Internet
    • Author: User
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    CompilationFan Dongdong

    Axsome Therapeutics today announced positive results from the Phase II Ascend clinical trial of major depressive disorder (MDD) therapy AXS-05, published in the American Journal of Psychiat.


    Results of the Phase II trial published here demonstrate rapid, substantial and statistically significant reductions in depressive symptoms and induction of remission in patients treated with AXS-05 compared to patients with moderate to severe MDD treated with bupropion alone improvement in meani.


    Therapy with AXS-05 entails taking a 45 mg tablet once daily for three days, followed by two daily doses for a total of six wee.


    Major depressive disorder is also known as clinical depressi.


    Typically, major depressive disorder is often treated with antidepressants, most commonly serotonin reuptake inhibitors (SSRI.


    Dan Iosifescu,.


    The AXS-05 therapy, with more than 40.


    In another Phase III GEMINI trial involving 327 adults with moderate-to-severe depression, AXS-05 therapy rapidly and significantly improved depressive symptoms compared with placebo, meeting the trial's primary endpoi.


    In addition, Axsome is also investigating the therapeutic's efficacy in Alzheimer's disea.


    Reference source:

    Axsome Takes New Approach, Targets NMDA Receptors to Treat Depression

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