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Find the "sweet spot" of sleep time that can slow down cognitive decline?
Time of Update: 2021-11-14
5 hours a night reported a significant decline in cognitive abilities over time, but those who slept in this range of The knowledge score remains stable .
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Stroke: Minor stroke, the more chronic diseases, the worse the treatment effect
Time of Update: 2021-11-13
CHANCE trial (clopidogrel in the treatment of patients at high risk of acute non-disabling cerebrovascular events) 2 and POINT trial (platelet-directed inhibition of new TIA and mild ischemic stroke) in the Chinese population, using clopidogrel and aspirin in combination Dual antiplatelet therapy (DAPT) has been shown to significantly reduce the risk of early new strokes in patients with MS or TIA .
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Ann Neurol: Improve hydrocephalus after hemorrhage in premature infants, pay attention to cerebrospinal fluid transferrin
Time of Update: 2021-11-13
Strahle studied patients with post-hemorrhagic hydrocephalus (PHH) who underwent (1) temporary and permanent cerebrospinal fluid (CSF) shunt and (2) infant development III Bailey scale tests at around 2 years of age .
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Neurology: Incidence, prevalence, longitudinal damage and disability of small fiber neuropathy
Time of Update: 2021-11-13
In this way, Stephen A Johnson of the Mayo Clinic and others evaluated the incidence and prevalence of SFN patients without large fiber involvement (pure) at the time of onset, and longitudinally evaluated the patients’ comorbidities and cumulative nervous system from a population perspective.
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Stroke: Posterior circulation ischemia, direct aspiration vs. stent removal, which is better?
Time of Update: 2021-11-13
In ischemic stroke patients with posterior circulation and great vessel occlusion, first-line aspiration has shorter operation time than stent retractor thrombectomy, better reperfusion effect, and better clinical effect .
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Lancet Psychiatry: Plasma long-chain fatty acids have a protective effect on schizophrenia
Time of Update: 2021-11-13
Associations between plasma fatty acid concentrations and schizophrenia: a two-sample Mendelian randomisation study [published online ahead of print, 2021 Nov 1].
Associations between plasma fatty acid concentrations and schizophrenia: a two-sample Mendelian randomisation study [published online ahead of print, 2021 Nov 1].
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Stroke: What factors determine the prognosis of disabled patients and thrombectomy treatment after stroke?
Time of Update: 2021-11-13
Due to concerns about poor results and potentially useless causes, stroke patients with pre-disability are excluded from randomized clinical trials regardless of the cause of the disability .
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Neurology: Patients with epilepsy, heart rate variability and mortality are related
Time of Update: 2021-11-13
This international, multicenter, retrospective, nested case-control study evaluated the short-term interictal episodes of patients who later died of SUDEP during the video- EEG monitoring (VEM) period obtained from electrocardiogram (ECG) records Heart rate variability and compare these measures with a live epilepsy control group .
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Neurology: Amyloid PET can predict the onset of Alzheimer's disease symptoms
Time of Update: 2021-11-13
2), after which almost all individuals accumulate amyloid at a relatively consistent rate until reaching a high level of amyloid load (SUVR 3.
The average time between amyloid load levels is used to estimate the age at which an individual reaches SUVR 1.
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Brain: Socioeconomic gap is related to accelerated retinal neurodegeneration in multiple sclerosis
Time of Update: 2021-11-13
Vasileiou and other research groups used high-sensitivity imaging tools such as optical coherence tomography (OCT) to assess whether socioeconomic status (SES) indicators are related to the disease progression of patients with multiple sclerosis, and to determine whether differential multiple sclerosis management or co- Does the disease mediate any observed SES-related effects ?Eleni S.
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JAMA Neurol: The relationship between increased seizures during rewarming and the outcome of neurodevelopmental abnormalities at 2-year follow-up
Time of Update: 2021-11-13
5°C every hour until it reaches normal temperatureChildren with epilepsy Recently, studies have explored whether epilepsy is more likely to occur during rewarming than in the previous period, and whether it is related to the abnormal outcome of asphyxiated newborns receiving hypothermia .
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Alz Res Therapy: Hereditary dementia, the regional distribution of tau protein is highly correlated with cognitive decline
Time of Update: 2021-11-13
Another ADAD study found that tau PET was only elevated in impaired individuals, and suggested that MTL tauopathy, including EC, may be less involved in ADAD compared with sporadic ADLongitudinal PET studies have demonstrated pathological changes in fragile sporadic AD populations, but in ADAD, longitudinal measurements of tau and Aβ PET, and measurements of brain structure and cognitive function have not been reported .
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JAMA Neurol: Turning a blind eye—a case report of visual negligence after isolated superior colliculus disease
Time of Update: 2021-11-13
Using Singlims for analysis and statistical analysis (Figure 2), comparing the patient's eye movement data with the eye movement data of 15 age- and gender-matched healthy controls (HC) confirmed the hypothesis that the left side is ignored and the gaze is significantly reduced And lower cumulative fixation duration (patient: 5.
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Aging Cell: Vitamin D receptor activation may increase the risk of Alzheimer's disease
Time of Update: 2021-11-13
The abnormal increase in VDR levels was found to be co-localized with Aβ plaques, gliosis, and autophagosomes, suggesting that VDR is non-genomic activation in the pathogenesis of AD .
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Lancet Neurol: Comparison of apixaban and non-anticoagulation after anticoagulation-related cerebral hemorrhage in patients with atrial fibrillation in the Netherlands (APACHE-AF)
Time of Update: 2021-11-13
In the recent APACHE-AF study, researchers evaluated the ratio of non-fatal strokes or vascular deaths in patients receiving apishaban and avoiding anticoagulation therapy in order to design larger trials Provide a basis .
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Mov Disord: Is it possible to suffer from Parkinson's, check glutathione and take a look
Time of Update: 2021-11-13
diagnosisOriginal sourcePlasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print, 2021 Oct 25].
28826Plasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print, 2021 Oct 25].
28826 Plasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print .
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Alz Res Therapy: Will cognitively normal elderly and high-intensity physical exercise make the brain more agile?
Time of Update: 2021-11-13
A recent 12-week elderly intervention study showed that compared with moderate-intensity exercise or stretching controls, high-intensity exercise has a greater improvement in memory .
The use of high-intensity exercise in the elderly is safe and provides an effective way to improve physical health.
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Neurology: The relationship between adolescent and adolescent body mass index and long-term risk of multiple sclerosis: a population-based study
Time of Update: 2021-11-13
Children Recently, researchers have prospectively studied the long-term relationship between the body mass index (BMI) of adolescents and young adults and the risk of multiple sclerosis (MS) in the population .
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JNER: Clinicians' views on wearable devices that track upper limb activity after stroke: a qualitative focus group study
Time of Update: 2021-11-13
The purpose of this study is to understand the views of clinicians for post-stroke upper limb activity tracking wearable device and its potential for use in the rehabilitation practice article published in "Neurology, Neurosurgery and Psychiatry" ( Journal of Neurology, Neurosurgery & Psychiatry ) .
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Movement Disorders: Diffusion imaging parameters can detect and predict Parkinson's progress
Time of Update: 2021-11-13
28838Diffusion Magnetic Resonance Imaging Detects Progression in Parkinson's Disease: A Placebo-Controlled Trial of Rasagiline [published online ahead of print, 2021 Nov 1].
28838 Diffusion Magnetic Resonance Imaging Detects Progression in Parkinson's Disease: A Placebo-Controlled Trial of Rasagiline [published online ahead of print, 2021 Nov 1] Mov Disord 2021; 10.
