Find the "sweet spot" of sleep time that can slow down cognitive decline?

Over time, too much or too little sleep will cause cognitive decline
.

But new research shows that there may be an "optimal time point" for sleep time that can stabilize cognitive function
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In a longitudinal study, researchers found that elderly people who sleep less than 4.
5 hours or more than 6.
5 hours a night reported a significant decline in cognitive abilities over time, but those who slept in this range of The knowledge score remains stable
.

In order to determine whether sleep can be used as a sign of Alzheimer's disease progression, the team of Dr.
Brendan Lucey from the University of Washington Sleep Medicine Center conducted this study
.

Yimaitong compiles and organizes, please do not reprint without authorization
.

Research Introduction Alzheimer's disease affects nearly 6 million Americans, and there is a close connection between sleep patterns and Alzheimer's disease
.

Dr.
Lucey said that the current challenge is to unravel the complex connection between sleep, AD and cognitive function
.

In this new study, the researchers monitored the sleep-wake activity of 100 participants for 4-6 nights.
These participants underwent an annual cognitive assessment and clinical research, including APOE genotyping, as Washington Part of the longitudinal study of the University Knight Center for Alzheimer's Disease Research
.

Participants also provided cerebrospinal fluid (CSF) total tau and amyloid-β42, and wore a small EEG on their foreheads while they were sleeping
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 Main findings: ➤The clinical dementia score (CDR) of most participants is 0, indicating that there is no cognitive impairment
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The 12 participants had a CDR>0, and most reported mild cognitive impairment
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As expected, CSF analysis showed more evidence of AD pathology in patients with baseline CDR>0
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 ➤Use the preclinical Alzheimer's Default Cognitive Comprehensive (PACC) score to measure the changes in cognitive function.
The score is composed of the results of a combination of neuropsychological tests, including the free and cue selective reminder test, and the revised version of the Wechsler Memory Scale.
Logical memory delayed recall test, the revised version of the Webster’s Adult Intelligence Scale's digital symbol replacement test, and a simple mental status check
.

Researchers found that there is an inverted U-shaped relationship between the PACC score and sleep time.
People who sleep less than 4.
5 hours or more than 6.
5 hours at night have a sharp decline in cognitive ability (both P<0.
001)
.

 The study concluded that as time goes by, the cognitive ability of the elderly who sleep less than 4.
5 hours or more than 6.
5 hours per night decreases significantly, but the cognitive scores of people who sleep within this range remain stable
.

 Dr.
Heather Snyder, vice president of medical and scientific relations at the Alzheimer's Association, pointed out that the study adds a series of evidence linking sleep and cognition, especially how sleep quality can optimize brain function
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Previous studies have shown that poor sleep quality increases the risk of dementia, and studies have shown that sleep time may have an impact on cognition
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In the future, research on sleep as a cognitive health intervention is needed, and sleep is an important aspect of overall health
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Clinicians should talk to patients about sleep issues as part of the discussion about patients’ health habits and health standards
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 Yimaitong compiled from: Sleep Time'Sweet Spot' to Slow Cognitive Decline Identified? -Medscape-Oct 26, 2021.