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Neurology: Patients with epilepsy, heart rate variability and mortality are related

 Last Update: 2021-11-13
 Source: Internet
 Author: User

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Sudden epilepsy death (SUDEP) is a common cause of death in patients with epilepsy and the second largest neurological cause of the total number of years of potential life lost

epilepsy

The existence and frequency of TCS significantly increase the risk of SUDEP

Heart rate variability (HRV) is a widely used method of measuring the nerve control of the heart

In the epilepsy cohort, the reduction of heart rate variability between seizures is related to drug resistance and chronicity of epilepsy, and indicates a less favorable outcome after epilepsy surgery

Heart rate variability may be a biomarker of SUDEP, but research is limited by methodology, including few records of SUDEP cases

In this way, Shobi Sivathamboo and others of Monash University in Australia speculate that heart rate variability can help identify high-risk patients with SUDEP who may benefit from more intensive epilepsy management interventions and risk mitigation strategies, such as night monitoring

manage

They use time and spectrum-based heart rate variability measurements

video

In the multivariate model, the normalized LFP of SUDEP cases was lower than that of the control group (comparison-11.

There is a negative correlation between the latency of LFP and SUDEP.

The increase in survival time from VEM to SUDEP is related to higher normalized high frequency power (HFP; p=0.

The important significance of this study lies in the discovery: the decrease of short-term LFP is related to SUDEP , and LFP is an effective biomarker of sudden death

Short-term LFP reduction is related to SUDEP

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