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Alzheimer Dementia: How do vascular risk factors affect brain and cognitive function?
Time of Update: 2021-09-18
The FINGER study recruited seniors with high cardiovascular risk factors, aging and dementia incidence (CAIDE) risk scores, and found that multi-domain interventions (diet, physical activity, VRF management ) for VRFs can help prevent cognitive decline .
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JAMA: Creatinine-Uric Acid Elevation Therapy Used to Delay the Progression of Early Parkinson's Disease Patients
Time of Update: 2021-09-18
In patients with early Parkinson’s disease, compared with placebo, inosine treatment has no significant effect in delaying clinical disease progression.
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Well-known experts from China Brain Health Month jointly teach cutting-edge technologies for Parkinson's disease treatment
Time of Update: 2021-09-18
Since 2000, September has been China Brain Health Month, and September 16 has been "China Brain Health Day" . Parkinson's disease is a common disease in cranial nerve diseases. The lesion is locate
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Stroke: White matter high signal burden and collateral circulation in patients with large vessel occlusive stroke
Time of Update: 2021-09-18
Cardiovascular Thrombosis Stroke The researchers enrolled patients with acute ischemic stroke who had continuous visits for endovascular thrombus removal from January 2015 to December 2017 due to anterior circulation and large blood vessel occlusion, and were recovered by fluid attenuation inversion-semi-automatic volume of magnetic resonance imaging The analysis evaluates the WMH volume (periventricular, deep and total volume) .
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Neurology: In patients with multiple sclerosis, depression may increase the risk of vascular disease and death
Time of Update: 2021-09-12
CardiovascularIn this way, Raffaele Palladino of Imperial College London and others evaluated whether the associations between depression, vascular disease, and mortality are different in patients with multiple sclerosis compared with a control group matched by age, sex, and general doctors .
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Stroke: The combination of ticagrelor and aspirin in the treatment of stroke has more advantages than disadvantages
Time of Update: 2021-09-12
In 11016 patients with acute mild to moderate ischemic stroke or TIA, randomized to receive ticagrelor combined with aspirin (ticagrelor-aspirin) or aspirin alone for 30 days, ticagrelor-aspirin decreased He suffered a stroke or death (main efficacy outcome), but to an absolute extent, severe bleeding (main safety outcome) increased .
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JAMA Neurol: Safety Study of Follow-up Antiplatelet Therapy in Patients with Cerebral Hemorrhage and Stroke
Time of Update: 2021-09-12
Spontaneous cerebral hemorrhage and stroke survivors receive antiplatelet drugs for the secondary prevention of major cardiovascular event risks.
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JAHA: Predictors of the progression of carotid artery intima-media thickness in adolescents
Time of Update: 2021-09-12
It can be seen that systolic blood pressure, arterial hypertension, low-density and non-high-density lipoprotein cholesterol, and alanine aminotransferase can predict the progression of cIMT in adolescents, although the level of risk factors is mainly within the established reference range .
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Neurology: A good lifestyle is conducive to brain health and cognitive function
Time of Update: 2021-09-12
Associations of the Life>001-->White matter hyperintensity and cerebrospinal fluid volume partially mediate the link between LIBRA and cognition .
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Stroke: After a stroke, how does the patient's long-term life function change?
Time of Update: 2021-09-12
Among post-stroke survivors, it is estimated that more than 20% are restricted in daily life (ADL), and more than 30% are restricted in instrumental ADL (IADL), and these percentages are affected by s
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JAMA Neurol: Insufficient sleep can lead to increased Aβ burden and cognitive decline in the elderly with normal cognition
Time of Update: 2021-09-12
Prolonged sleep is associated with poor performance in multiple cognitive areas, which is related to shortened or delayed sleep time leading to an increase in body mass index, aggravation of depressive symptoms, and daytime naps .
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Stroke: After a stroke, blood pressure management, there are ethnic differences
Time of Update: 2021-09-12
The important significance of this study is that it found that compared with white adults with or without stroke, blacks have a lower rate of blood pressure control, and there is no statistically significant difference after multivariate adjustment .
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Neurology: Concussion can cause changes in the blood flow and structure of the midline brain structure
Time of Update: 2021-09-12
The important significance of this study lies in the discovery: HOC has subacute and chronic effects on the cingulate gyrus CBF and corpus callosum microstructure, but there is no difference in clinical index .
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Neurology: Safety of Occrelizumab in patients with different types of multiple sclerosis
Time of Update: 2021-09-12
The most common serious AEs (including SI And malignant tumors) The incidence is consistent with the scope of the epidemiological data reportIn summary, whether it has been continuously used in clinical trials for up to 7 years or widely used in the real world for more than 3 years, Ocrelizumab is safe in patients with relapsing or primary progressive multiple sclerosis .
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Stroke: What are the clinical features of reversible cerebral vasoconstriction syndrome?
Time of Update: 2021-09-12
S. population, more than 1,000 RCVS patients are hospitalized each year, most of them are middle-aged women , and about 300 need at least some rehabilitation or nursing home care after they are discharged from the hospital .
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Stroke: After heart transplantation, what are the risk factors and outcome of stroke?
Time of Update: 2021-09-12
Compared with maintenance therapy with calcineurin inhibitors, switching from calcinein inhibitors to sirolimus-based immunosuppression was not associated with a significant change in stroke risk (HR, 1.
Stroke and ischemic events of any type were independently associated with increased risk of death (HR, 1.
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Neurology: Relapsing-remitting multiple sclerosis, which test is more accurate in assessing the prognosis of its disability?
Time of Update: 2021-09-12
In this way, they studied EDSS as a disability outcome, including different presentation methods and statistical processing of the outcome data, and compared it with the alternative outcome measures T25FW and NHPT .
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JAMA Sub-Journal: Outstanding Achievement in Stroke First Aid——Comparison of the triage of stroke patients in different stroke centers
Time of Update: 2021-09-11
08%) There is no slope change, which indicates a stepwise rather than a gradual changeIn summary, the implementation of the pre-hospital transfer policy of comprehensive stroke center triage is related to the significant, rapid and continuous increase in the EVT rate of AIS patients, but is not harmfully related to the thrombolysis rate or time .
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JAMA Neurology: In a football game, which athletes are more likely to suffer from neurodegenerative diseases?
Time of Update: 2021-09-11
Former professional contact sports are believed to have a higher mortality rate from dementia and a range of other neurodegenerative diseases, including motor neuron disease and Parkinson’s diseaseHowever, it is still uncertain whether the risk of neurodegenerative disease in former athletes is related to TBI and repeated head impact exposure or other unidentified factors .
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Neurosci Biobehav Rev: Terrible!
Time of Update: 2021-09-11
The analysis results showed that compared with individuals with small waist circumference, large waist circumference was associated with a higher risk of cognitive dysfunction and dementia (hazard ratio [HR] 1.
Central obesity assessed by waist circumference is associated with the risk of cognitive impairment and dementia, especially in people over 65 years of age.
