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JAMA Sub-Journal: Outstanding Achievement in Stroke First Aid——Comparison of the triage of stroke patients in different stroke centers
Time of Update: 2021-09-11
08%) There is no slope change, which indicates a stepwise rather than a gradual changeIn summary, the implementation of the pre-hospital transfer policy of comprehensive stroke center triage is related to the significant, rapid and continuous increase in the EVT rate of AIS patients, but is not harmfully related to the thrombolysis rate or time .
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JAMA Neurology: In a football game, which athletes are more likely to suffer from neurodegenerative diseases?
Time of Update: 2021-09-11
Former professional contact sports are believed to have a higher mortality rate from dementia and a range of other neurodegenerative diseases, including motor neuron disease and Parkinson’s diseaseHowever, it is still uncertain whether the risk of neurodegenerative disease in former athletes is related to TBI and repeated head impact exposure or other unidentified factors .
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Neurology: Artificial intelligence, assists in the diagnosis of temporal lobe epilepsy
Time of Update: 2021-09-11
The accuracy of the classifier was further evaluated in two independent TLE cohorts with similar demographic and electroclinical characteristics (n=57; 58% MRI negative) .
An MRI-Based Machine Learning Prediction Framework to Lateralize Hippocampal Sclerosis in Patients With Temporal Lobe Epilepsy.
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Alzheimers Res Ther: Body mass index in middle age is negatively correlated with abnormal folding of plasma Aβ
Time of Update: 2021-09-11
Preventing to determine whether the risk factors of Alzheimer's disease clinical syndrome (clinical AD), such as body mass index (BMI), are related to Aβ misfolding in the blood (an important indicator of the risk of AD in the elderly)The ESTHER study is a population-based cohort study of German elderly (50-75 years old) that collected information about risk factors and blood samples from subjects at baseline .
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JNNP: Comparison of cerebrospinal fluid and serum neurofilament light and heavy chains as biomarkers for differential diagnosis of ALS
Time of Update: 2021-09-11
Cerebrospinal fluid (CSF) and serum neurofilament light chain (NfL) and heavy chain (NfH) levels in patients with ALS are elevated compared with most other neurological diseases .
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Nat Commun: Long-term use of Dasatinib and Quercetin can improve intervertebral disc degeneration
Time of Update: 2021-09-11
The characteristics of intervertebral disc degeneration include extracellular Decrease in the abundance and quality of the matrix (ECM), loss of biomechanical properties, increase in inflammatory mediators and catabolic processes, and changes in cell phenotype and deathStudies on human tissues and mouse models have shown that the incidence of senescent cells increases during the aging and degeneration of intervertebral discs .
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Eur Heart J: The incidence and mortality of ischemic stroke in patients with acute coronary syndromes with atrial fibrillation detected for the first time
Time of Update: 2021-09-11
Recently, the heart blood vessels magazine field authority Eur Heart published a research article on J, the study was designed to assess the acute coronary syndrome (ACS) survivors and contemporary data first detected atrial fibrillation (AF) patients with 1-year prognosis .
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JAMA Neurology: In the blood, the phosphorylated tau protein is different, and the clinical prediction significance is different
Time of Update: 2021-09-11
In the past two years, some studies have shown that plasma p-tau181, p-tau217 and p-tau231 are indicators of amyloid and tau pathology in the clinical AD spectrum, which can distinguish AD dementia from other neurodegenerative diseases Come .
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Mov Disord: Surprise!
Time of Update: 2021-09-11
In summary, the results of the study show that late menopause is associated with a reduced risk of Parkinson's disease in women, and supports the hypothesis that sex hormones or other factors related to late menopause may have a neuroprotective effect on PD .
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JAMA Neurology: After stroke, is fluoxetine effective in alleviating depression symptoms?
Time of Update: 2021-09-11
Recently, 3 large randomized, double-blind, placebo-controlled clinical trials studied the effects of fluoxetine on stroke patients, in which depression was recorded as a secondary outcome .
To study whether the use of 20 mg of fluoxetine hydrochloride per day can reduce the proportion of people who have clinically significant depressive symptoms after stroke .
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JNNP: Coronavirus disease does not increase the short-term risk of clinical recurrence of multiple sclerosis
Time of Update: 2021-09-11
The purpose of this study is to evaluate the short-term risk of clinical relapse several months after the first vaccination of pwMS with mRNA COVID-19 vaccine .
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JNER: Low-frequency deep brain stimulation can improve the acute gait of Parkinson's disease patients
Time of Update: 2021-09-11
Participating patientsParticipating patientsThe analysis of the linear mixed model that controls walking speed shows that during the gait test, stimulation (low frequency and high frequency) has a significant main effect on the ML and VT rhythm of the trunk .
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JAMA Neurology: After cerebral hemorrhage, which epilepsy prevention method is better?
Time of Update: 2021-09-11
Therefore, Felipe JS Jone and others at Harvard University Massachusetts General Hospital used simulation model and decision analysis, combined with current knowledge, according to the type of treatment (primary and secondary prevention), the time of the event ( Early and late onset) and duration of treatment (1 week [short-term] and indefinite [long-term] treatment), to evaluate the trade-offs related to the 4 treatment strategies .
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Stroke: Coagulation and inflammation biomarkers in patients with COVID-19-related ischemic stroke
Time of Update: 2021-09-11
Heart blood vessels COVID-19 StrokeResearchers performed machine learning cluster analysis on common biomarkers of ischemic stroke patients admitted to the hospital due to severe acute respiratory syndrome coronavirus 2 infection to determine whether they are related to AIS .
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Neurology: Ocrelizumab, the treatment of progressive multiple sclerosis, how safe is it?
Time of Update: 2021-09-11
In the controlled treatment phase (CTPs) of the pivotal Phase 3 trial, infusion-related reactions (IRRs), respiratory infections, and urinary tract infections (UTIs) were the most common adverse events (AEs) associated with OCR .
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JAHA: Cardiac hypertrophy is related to brain aging
Time of Update: 2021-09-11
It can be seen that LV diameter and quality are associated with lower overall and regional CT and greater burden of WMH in the general population .
LV diameter and quality are associated with lower overall and regional CT and a greater burden of WMH in the general population .
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JNNP: Clinical significance of deep brain stimulation in the treatment of advanced Parkinson's disease with stimulation-induced dyskinesia
Time of Update: 2021-09-11
Deep brain stimulation (DBS) has been shown to be effective in improving the motor symptoms of advanced Parkinson's disease (PD) and reducing levodopa-induced dyskinesia (LID) .
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FDA approves the first stroke rehabilitation device-Vivistim for vagus nerve stimulation
Time of Update: 2021-09-10
Vivistim is a Vagus Nerve Stimulation (VNS) device that is used to restore motor function to people who have lost hand and arm mobility due to ischemic stroke .
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Neurology: New immigrants to Canada have a lower incidence of stroke
Time of Update: 2021-09-10
Vyas and others of the University of Toronto in Canada conducted a population-based retrospective cohort study to assess the relationship between immigration status and stroke (ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage) or transient The relationship between the incidence of ischemic attack (TIA) and the type of stroke .
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[In-depth analysis] Diagnosis of peripheral neuropathy, just read this one!
Time of Update: 2021-09-10
If the condition permits, try to exercise at least three times a week, 30 minutes to 1 hour each time;-Avoid factors that may cause nerve damage, including repetitive movements, restricted positions, exposure to toxic chemicals, smoking, and alcohol abuse .
