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Neuromodulation: Some less studied aspects of deep brain stimulation for Parkinson's disease: implant surgery, hospitalization, and death
Time of Update: 2021-06-29
Patients with DBS implantation after 65 years of age were hospitalized and had a higher mortality rate .
Patients with DBS implantation after 65 years of age were hospitalized and had a higher mortality rate .
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Human Brain Mapping: Reproductive history is related to the age of white matter in middle-aged and elderly women
Time of Update: 2021-06-29
The results showed that there was a negative correlation between birth history and white matter brain age, which may indicate that childbirth has a protective effect on white matter in future life .
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Science Zhu Hongtu team's 40,000 brain images reveal the genetic basis of human white matter for the first time
Time of Update: 2021-06-29
Researchers conducted a genome-wide study (GWAS) on diffusion magnetic resonance images (dMRI) and DNA of more than 40,000 people, and identified 151 gene regions that affect the white matter of the brain, thereby clarifying how genetics can cause differences in the white matter of individual brains (Figure 1) ) .
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Neurology: Intravascular thrombus removal + intravenous thrombolysis, the treatment of large blood vessel strokes will benefit more
Time of Update: 2021-06-28
At the same time, a recent meta-analysis of 30 studies showed that compared with EVT alone, patients who received EVT+IVT obtained significantly better functional results, and this association was still significant after the propensity score was matched .
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Progress in Metz Neurology (Issue 005)
Time of Update: 2021-06-28
Editor's note: Metz Medicine will regularly summarize the latest developments in the neurological field . The following is the latest neurological development presented to you . enjoy ~Editor's no
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Neurology: How to efficiently evaluate peripheral neurotoxicity caused by chemotherapy
Time of Update: 2021-06-28
Among 153 participants who had no neuropathy at baseline and received chemotherapy with known neurotoxicity, the moderate correlation between TNSc and TNSn scores and FACT/GOG-NTX was verified (Spearman correlation index r=0.
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Because the CEO was accused of tampering with data and other academic misconduct, the market value of Athira Pharma directly evaporated 1.7 billion yuan a day
Time of Update: 2021-06-28
On the evening of June 17, 2021, the company announced that CEO Leen Kawas had been temporarily suspended, awaiting the board of directors to review actions related to Kawas’ doctoral studies at Washington State University .
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Massachusetts General Hospital found that the implantable chip can more accurately identify patients at risk of stroke recurrence...
Time of Update: 2021-06-23
Recent studies have shown that a small chip implanted under the skin can monitor heart rate and rhythm, and help doctors detect atrial fibrillation in patients who have experienced cryptogenic stroke .
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The patient has skin itching and cramps, this disease cannot be ignored!
Time of Update: 2021-06-22
When Zhou Feng was seeing Xiong Qing, she was once confused by her skin itching, because of the core symptoms of NMOSD, including: optic neuritis, long-segment myelitis, and posterior zone syndrome (refractory hiccups and vomiting) ), diencephalic syndrome (drowsiness), etc.
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[New research] At what age do you remember your earliest memory?
Time of Update: 2021-06-22
Author: Yun Introduction: Researchers believe that most adults have "childhood amnesia" and can't remember things about infants and young children .
Research shows that, on average, the earliest memories people can recall can be traced back to when they were two and a half years old .
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Cell Journal: Restoring miRNA expression can save Alzheimer's disease...
Time of Update: 2021-06-22
First, the researchers performed postmortem immunohistochemical analysis on the neuronal progenitor cells proliferating in the subgranular region of the dentate gyrus of the hippocampus in tissue sections of 10 non-dementia control individuals and 10 Alzheimer's disease patients, which confirmed that they are in AD Mid-adult neurogenesis was pathologically damaged, and it was confirmed in a mouse model that the brain pathological damage in AD was related to the level of miR-132 in the adult hippocampal neurogenic niche .
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Bayer strongly deploys Parkinson's innovative therapies, stem cell and gene therapy have entered the clinical stage, Yi Mai Meng broke the news
Time of Update: 2021-06-22
Recent popular reports from Yimaike ★ Invitation to the grand event 2021 Oncolytic Virus Drug Development Forum is about to open in Shanghai ★ The financing has been hundreds of millions in half a ye
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Yizheng Wang's team reveals that synaptic plasticity can regulate movement control
Time of Update: 2021-06-22
Parkinson's disease model" research paper, which shows that the synaptic plasticity of the STN-ANT loop controls the locomotion behavior of PD model rodents .
In summary, this study shows that the synaptic plasticity of the STN-ANT loop controls the locomotion behavior of PD model rodents .
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Be careful not to hit the pit of the contrast agent!
Time of Update: 2021-06-22
Low toxicity, low osmotic pressure and non-ionic iodine contrast agents have been used in more and more clinical applications, but the side effects and adverse reactions that follow are also called influences.
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Nat Comm Gao Tianming's team found that abnormal astrocyte function can lead to autism
Time of Update: 2021-06-22
The authors used gene knockout technology to prepare IP3R2 whole body knockout mice (KO) and astrocyte conditional knockout mice (cKO), and performed behavioral screening, and found KO and cKO mice All showed abnormal calcium signal in astrocytes and the core symptoms of autism, namely impaired social function and repetitive stereotyped behaviors .
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Understand the scale strategy of ischemic cerebrovascular disease in seconds
Time of Update: 2021-06-22
*Only for medical professionals to read and remember, but also to be able to use it! As a neurology novice who is new to the workplace, the scoring scale taught by the teacher when he was studying wa
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Cell Stem Cell targeting miR-132 may save adult hippocampal neurogenesis and memory deficits in AD patients
Time of Update: 2021-06-22
This study reported that miR-132 regulation is an integral part of AHN, and supplementary miR-132 plays different roles in the adult hippocampal neurogenesis microenvironment, thereby in two Recovery of AHN and memory deficits in different AD mouse models .
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Research reveals the neural mechanism for efficient decision-making in dynamic multi-value options
Time of Update: 2021-06-22
The study found that the superior colliculus neuron first characterizes the absolute value of the next selected target in the eye movement decision-making process, and this characterization is not affected by the value of other options .
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How to prevent cardiogenic strokes of different etiologies?
Time of Update: 2021-06-22
Figure 4 In addition to new anticoagulant drugs for interventional treatment of patients with atrial fibrillation combined with PCI, another popular treatment method in recent years is left atrial appendage closure (LACC) to prevent cardiogenic stroke .
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Professor Du Yifeng: What issues should be paid attention to in AD diagnosis?
Time of Update: 2021-06-22
*Only for medical professionals to refer to the diagnostic criteria, diagnostic markers, timing and content of detection. . . Alzheimer's disease (AD) is the most common neurodegenerative disease wit