-
Ebiomedicine: Cholesterol may help treat Alzheimer's disease and diabetes
Time of Update: 2021-04-20
March 26, 2021 //---According to a recent study, scientists from the University of Arizona School of Health Sciences examined the role of cholesterol in Alzheimer’s disease and type 2 diabetes to identify the potential for regulating the brain Cholesterol level is a small molecule, and may become a potential new therapeutic target for Alzheimer's disease.
-
Brain Commun: Research reveals the impact of key proteins on epilepsy
Time of Update: 2021-04-20
html">Study maps key proteins linked to epilepsy, revealing new drug targets Original source: Geoffrey Pires, Dominique Leitner, Eleanor Drummond et al, oup.
html">Study maps key proteins linked to epilepsy, revealing new drug targets Original source: Geoffrey Pires, Dominique Leitner, Eleanor Drummond et al, oup.
-
The latest data! Can this DMD gene therapy, which has been suspended for more than a year, effectively improve the patient's condition 丨 Yimai Meng broke the news
Time of Update: 2021-04-20
MedClub broke the news March 25, 2021/eMedClub News/--Recently, at the MDA virtual clinical and scientific conference, Solid announced the latest clinical research results for Duchenne muscular dystrophy (DMD).
Participants who successfully registered for the Shanghai 2021 BPIT conference will receive a limited edition of "CAR-T Cell Therapy Industry Research Report" 2021.
-
Brain: Women accumulate Alzheimer's disease-related proteins at a higher rate
Time of Update: 2021-04-20
First author Ruben Smith explained: “In the temporal lobes of the brain of patients affected by Alzheimer’s disease, the overall cumulative rate of women is 75% higher than that of men.
-
IL-4 improves stress tolerance and reduces depression
Time of Update: 2021-04-20
) Pro-inflammatory cytokines in mental diseases (Document 1) Since pro-inflammatory cytokines are involved in inducing mental diseases, cytokines that inhibit inflammation, such as Can IL-4 enhance the body's tolerance to stress and resist the occurrence of depression?
-
There is a new vaccine for malignant brain tumors! Early trials are safe and effective (with introduction of other brain tumor vaccines)
Time of Update: 2021-04-20
Encouraged by these results, Platten and a team of doctors decided to test a mutation-specific vaccine in patients newly diagnosed with IDH1 mutant gliomas (WHO grades III and IV astrocytomas) for the first time in a phase I study.
-
Why Stumble Around After Being Drunk—Professor Zhang Li reveals that cerebellar astrocytes mediate dyskinesia in alcoholism
Time of Update: 2021-04-20
After specifically knocking out ALDH2 on astrocytes, the concentration of acetaldehyde in peripheral and cerebellar tissues was no different from that of normal mice, but the concentration of alcohol metabolite acetate in peripheral and cerebellar tissues was significantly reduced.
-
The ideal disease-modifying drug for multiple sclerosis under the new crown epidemic, have you chosen the right one?
Time of Update: 2021-04-20
Among the DMT drugs that can be used safely under the epidemic situation recommended by the guidelines, teriflunomide does not cause severe immunosuppression, does not increase the risk of infection, and does not affect the effectiveness of inactivated vaccination.
-
Express | Sword refers to neurological diseases that plague tens of millions of patients, Xinrui has received 80 million US dollars to promote two clinical treatments
Time of Update: 2021-04-20
▲ETX-810 reduces neuroinflammation and pain by increasing PEA levels (picture source: Eliem's official website) The company's other clinical phase research therapy ETX-155 is a new generation of oral GABAA receptor positive allosteric modulation Agent.
-
Research finds that non-invasive brain stimulation can improve the cognitive and physical health of the elderly
Time of Update: 2021-04-20
com/tags/%E6%8A%91%E9%83%81%E7%97%87/">DepressionTo this end, Li Juan, a researcher from the Institute of Psychology, Chinese Academy of Sciences, conducted a series of studies to explore the effects of non-invasive brain stimulation on the cognitive ability and cardiovascular health of the elderly and its mechanism of action, including a tDCS meta-analysis study, A tDCS intervention study and an rTMS intervention study.
-
Latest research progress of CRISPR/Cas in March 2021
Time of Update: 2021-04-19
1038/s41467-021-21559-9 Nat Commun: Scientists have developed new gene editing tools to correct human genetic diseases mutationImage source: Agency for Science, Technology and Research (A*STAR), Genome Institute of Singapore (GIS).
html" target="_blank">Stem Cells: GLI1 gene can help treat a variety of cancers doi: 10.
-
ISC on the sword: Carotid artery stenosis, radical treatment or conservative observation?
Time of Update: 2021-04-19
Asymptomatic Carotid Surgery Trial (ACST) showed that patients with stenosis greater than 70%, given medication, the risk of stroke was significantly reduced.
04 Symptomatic carotid artery stenosis should be selected for appropriate surgical treatment Figure 4: Professor PPTSaeid Shahidi introduced a meta-analysis of carotid artery stent (CAS) and CEA comparative trials.
-
The latest research progress of neural stem cells (Phase 5)
Time of Update: 2021-04-19
html" target="_blank">Sci Rep: Research reveals that adult neural stem cell biomarkers doi:10.
html" target="_blank">Sci the Rep: Adult neural stem cell studies revealed biomarker bioon.
html" target="_blank">Nature: Neural progenitor cells from the central nervous system promote neurogenesis in cancer doi:10.
-
New medicine for migraine!
Time of Update: 2021-04-19
Data from the Phase 3 ADVANCE study showed that during the 12-week treatment period, compared with placebo, all doses (10mg, 30mg, 60mg) of atogepant significantly reduced the average monthly migraine days from baseline.
-
Unhelpful?
Time of Update: 2021-04-19
Stuart Lipton, a professor in the Department of Molecular Medicine at the Scripps Research Institute, said that the inflammatory response observed in the study may offset the beneficial effects of antibody therapy.
-
Neurobiology of Aging︱ Sleep and Rhythm Aging Variations and Pathological Variations
Time of Update: 2021-04-19
For example, Kun Hu, Peng Li and Lei Gao from Brigham and Women's Hospital and Harvard Medical School published a review article in the journal "Sleep, Static-Motion Rhythm and Ageing: the complex network of Alzheimer's disease" (Letter to the editor: Sleep, rest-activity rhythms and aging: A complex web in Alzheimer's disease?) [4].
-
Nature | The fourth treatment?
Time of Update: 2021-04-19
According to the above-mentioned early exercise training can significantly improve the cognitive impairment of Rett mice, the researchers believe that the neurons activated during the training period may be the key to the above-mentioned therapeutic effects.
In general, this article found that early exercise intervention can effectively improve motor dysfunction and cognitive impairment in Rett mice.
-
Patients with transient ischemic attack have frequent blackouts after treatment. It turned out to be...
Time of Update: 2021-04-19
*Only for medical professionals to read and reference [Review the classics] Lung cancer complicated by reversible posterior leukoencephalopathy syndrome Reversible posterior encephalopathy syndrome (Posterior reversible encephalopathy syndrome, PRES) is of bilateral occipital parietal symmetrical vascular origin Edema is an imaging feature, and its clinical symptoms are mainly headaches, seizures, disturbances of consciousness, visual disturbances and other encephalopathy symptoms.
-
One article to master: Clinical manifestations of hepatic encephalopathy | Clinical essentials
Time of Update: 2021-04-19
Hepatic encephalopathy (HE) refers to a large group of syndromes in which neurological and neuropsychiatric abnormalities appear on the basis of liver disease.
In the case of persistent HE, symptoms of Parkinson's disease related to liver cirrhosis may appear, leading to extrapyramidal reactions, including dull face, slow movement, and muscle tremor.
-
Neuron | Draw and analyze the "architectural drawings" of the brain microvascular network
Time of Update: 2021-04-19
March 2, 2021, the David Kleinfeld laboratory of the Department of Physics and the Department of Neurobiology, University of California, San Diego, and the Howard Hughes Medical Institute Janelia Research Park MouseLight team (the first author is Ji Xiang, Department of Physics, University of California, San Diego) In the Neuron article "Brain microvasculature has a common topology with local differences in geometry that match metabolic load", the microvascular network of the whole brain of mice was measured, reconstructed and analyzed.
