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Neurology: How to efficiently evaluate peripheral neurotoxicity caused by chemotherapy

 Last Update: 2021-06-28
 Source: Internet
 Author: User

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Chemotherapy-induced peripheral neurotoxicity (CIPN) caused by widely used anticancer drugs is a major problem in daily oncology practice

prevention

One of the main reasons for the lack of effective treatment is the incomplete understanding of the pathogenesis of CIPN

According to some previous methodological studies, the measurement method combining clinician reports (CROs) and patient-reported results (PROs) seems to be the most reliable method

A measurement method that combines clinician reports (CROs) and patient-reported results (PROs) seems to be the most reliable method

The assessment is performed before and at the end of chemotherapy

The moderate correlation between TNSc and TNSn scores and FACT/GOG-NTX was verified (Spearman correlation index r=0.

The MCID of TNSc and TNSn has been calculated.

TNSn can be considered a reliable alternative objective clinical assessment TNSn can be considered a reliable alternative objective clinical assessment

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