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Downward anorexia, upward binge eating?
Time of Update: 2021-05-08
After the researchers injected the MC3R specific agonist C18 into the brain ventricle, wild-type mice developed severe appetite, which promoted food intake by more than 50% 6 hours after the administration.
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The diagnosis and treatment of cognitive impairment after stroke are done in one article
Time of Update: 2021-05-08
*It is only for medical professionals to read and refer to the current hot topics of stroke research and intervention in the world. Stroke has received more and more attention due to its high incide
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JAMA Netw Open: Sleepwalkers have a 4 times higher risk of Parkinson's disease than ordinary people!
Time of Update: 2021-05-08
After adjusting for possible confounding factors, including age, smoking, caffeine intake, chronic disease status, and other sleep disorders, the researchers found that sleepwalking men had a four- fold higher risk of PD and a six- fold increase in the risk of RBD .
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Science Sub-Journal: iPSC-derived cell therapy successfully repairs brain damage in mice | Yimai Meng broke the news
Time of Update: 2021-05-08
A study by the University of California, Los Angeles (UCLA) found that glial cells derived from artificially induced pluripotent stem cells (iPSC) were injected into the brains of mice with stroke and dementia , Found that this method successfully repaired brain damage and improved memory function.
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JNNP: Hemiplegic ALS: Clinicopathological Features of Two Autopsy Patients
Time of Update: 2021-05-08
In amyotrophic lateral sclerosis (ALS), it is not clear how the initial lesions develop and further expand in the upper and lower motor neuron (UMN and LMN) systems.
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Circulation | Big Discovery: "Good Cholesterol" can both anti-inflammatory and protect the cardiovascular system
Time of Update: 2021-05-08
prevention Although in the general population, the circulating level of HDL-C is inversely proportional to the risk of CVD, the results of drug intervention trials aimed at increasing plasma HDL-C are often negative.
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Improve cell "cleaning" ability, or can treat Alzheimer's disease | Cell
Time of Update: 2021-05-08
Ana Maria Cuervo Image source: Albert Einstein College of Medicine As people age, the efficiency of CMA gradually decreases, and the risk of unnecessary protein accumulating into insoluble masses that damage cells is also gradually increasing.
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Neurology: People who exercise regularly have better cognitive ability!
Time of Update: 2021-05-08
0000000000011852" target="_blank" rel="noopener">_APOE_ and the Activity of the Physical Association or with Genotype With Early Longitudinal Cognitive Change in the PD neurology.
0000000000011852" target="_blank" rel="noopener">_APOE_ and the Activity of the Physical Association or with Genotype With Early Longitudinal Cognitive Change in the PD neurology.
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IEEE Trans: Correlation analysis between EEG network and modulated acoustic stimulation in patients with chronic tinnitus
Time of Update: 2021-05-08
org/document/9265342" target="_blank" rel="noopener">Correlation Analysis of EEG Brain Network With Modulated Acoustic Stimulation for Chronic Tinnitus Patients ," in ieee.
org/document/9265342" target="_blank" rel="noopener">Correlation Analysis of EEG Brain Network With Modulated Acoustic Stimulation for Chronic Tinnitus Patients IEEE Transactions on Neural Systems and Rehabilitation Engineering , vol.
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Nature Sub-Journal | Thirty-year cohort data reminder: middle-aged people sleep less, and dementia can't escape!
Time of Update: 2021-05-08
Short sleep time in middle age is related to a higher risk of dementia in the future, and has nothing to do with sociodemographic, behavioral, cardiometabolic and mental health factors.
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NAT COMMUN: Insufficient sleep, beware of dementia coming to you!
Time of Update: 2021-05-08
After adjusting for healthy behavior, cardiometabolic and mental health factors, the correlation between sleep time and the incidence of dementia has been weakened, but for people aged 50 and 60 , insufficient sleep time is still associated with a high incidence of dementia.
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JAHA: Gender differences in carotid plaque composition in patients with embolic stroke of unknown origin
Time of Update: 2021-05-08
The researchers compared the volume of plaque components (calcium, intraplaque hemorrhage [IPH], and lipid-rich necrotic core) by gender, and compared the stroke on the same side with the contralateral side through a paired analysis.
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Eur Radiol: The value of MRI in differentiating benign and malignant peripheral nerve sheath tumors
Time of Update: 2021-05-08
diagnosis Recently, a study published in the journal European Radiology evaluated the potential of conventional MRI and diffusion-weighted imaging (DWI) to differentiate between benign and malignant peripheral nerve sheath tumors (PNSTs), and accurate characterization of PNSTs through non-invasive imaging techniques to avoid inconvenience.
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Alzheimer Dementia: Controlling blood pressure in middle age reduces the risk of dementia
Time of Update: 2021-05-08
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels in diabetic myocardial infarctionSome cohort studies have explored the relationship between the LS7 score and the risk of dementia or cognitive decline in later life, but the results are not consistent.
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Alzheimer Dementia: Extrapyramidal symptoms can effectively predict the risk of dementia
Time of Update: 2021-05-08
The results of previous studies have shown that the presence of EPS at baseline and the presence of time-varying EPS (capturing the incidence of EPS during follow-up) predicts shorter time to death, cognitive, functional and dependent endpoints, and cognitive The rate of decline is greater.
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Cell Stem Cell Back-to-Back | Ten Years of Grinding a Sword: Development of hPSCs-derived dopamine neuron optimization program and preclinical efficacy evaluation
Time of Update: 2021-05-08
In PD models of mice, rats, and monkeys, the robust implantation of in vitro hPSC-derived mDA neurons requires the development of a floor-derived midbrain dopamine neuron differentiation protocol, and all of these protocols are based on WNT signal activators (usually GSK3).
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This method can quantitatively evaluate the delay time of multiple sclerosis treatment?
Time of Update: 2021-05-08
Research conclusions This study has developed a new method and conducted external verification, which can objectively quantify the treatment lag duration of recurrence and disability progression in different treatments.
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IEEE trans: Application of muscle synergy analysis in gait in patients with knee osteoarthritis
Time of Update: 2021-05-08
Muscle synergy analysis may be useful for musculoskeletal diseases where the focus is on the characteristic module structure of spatial components, rather than comparing the number of modules.
Muscle synergy analysis may help to explore the characteristics of other musculoskeletal diseases in future research, focusing on abnormal components in muscle activity.
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JNNP: Early atypical signs and hypometabolism of insula can predict the survival rate of patients with multiple system atrophy
Time of Update: 2021-05-08
So far, research on survival rates basically includes clinical data, and only one person believes that 18F-FDG positron emission tomography (PET) metabolism is a potential predictor of survival for patients with atypical Parkinson's disease.
Diagnosis In this MSA patient cohort study, the goal is to find survival predictors in clinical and cerebral PET metabolic characteristics.
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IEEE trans: Hand Gesture Classification and Correction Method for Family Therapy Training of Adolescent Cerebral Palsy
Time of Update: 2021-05-08
org/document/9262937/references#references" target="_blank" rel="noopener">A Classification and Calibration Procedure for Gesture Specific Home-Based Therapy Exercise in Young People With Cerebral Palsy, " in ieee.
org/document/9262937/references#references" target="_blank" rel="noopener">A Classification and Calibration Procedure for Gesture Specific Home-Based Therapy Exercise in Young People With Cerebral Palsy, IEEE Transactions on Neural Systems and Rehabilitation Engineering , vol.
