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Alzheimers Res Ther: Body mass index in middle age is negatively correlated with abnormal folding of plasma Aβ

 Last Update: 2021-09-11
 Source: Internet
 Author: User

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Assessing the association between Alzheimer's disease risk factors and early pathological changes will help reveal the potential of early intervention and preventive measures for Alzheimer's disease

Preventing to determine whether the risk factors of Alzheimer's disease clinical syndrome (clinical AD), such as body mass index (BMI), are related to Aβ misfolding in the blood (an important indicator of the risk of AD in the elderly)

The ESTHER study is a population-based cohort study of German elderly (50-75 years old) that collected information about risk factors and blood samples from subjects at baseline

immunity

(A) BMI changes in subjects with or without Aβ misfolding; (B) BMI changes in subjects with or without clinical AD

According to the reported historical weight, BMI at age 50 was negatively correlated with Aβ misfolding (aOR 0.

BMI at 50 years old was negatively correlated with Aβ misfolding (aOR 0.

Original source:

Möllers Tobias, Stocker Hannah, Perna Laura et al.

Aβ misfolding in blood plasma is inversely associated with body mass index even in middle adulthood

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